Evaluated articles

Identification of a conserved S2 epitope present on spike proteins from all highly pathogenic coronaviruses

1. Rui P Silva
2. Yimin Huang
3. Annalee W Nguyen
4. Ching-Lin Hsieh
5. Oladimeji S Olaluwoye
6. Tamer S Kaoud
7. Rebecca E Wilen
8. Ahlam N Qerqez
9. Jun-Gyu Park
10. Ahmed M Khalil
11. Laura R Azouz
12. Kevin C Le
13. Amanda L Bohanon
14. Andrea M DiVenere
15. Yutong Liu
16. Alison G Lee
17. Dzifa A Amengor
18. Sophie R Shoemaker
19. Shawn M Costello
20. Eduardo A Padlan
21. Susan Marqusee
22. Luis Martinez-Sobrido
23. Kevin N Dalby
24. Sheena D'Arcy
25. Jason S McLellan
26. Jennifer A Maynard

• Curated by eLife

  eLife assessment

  Silva and colleagues present useful findings related to the isolation of an anti-S2 antibody that recognizes a previously uncharacterized SARS-CoV2 Spike (S) epitope, adding to the growing repertoire of anti-S antibodies that broadly cross-react against human and zoonotic coronaviruses. The evidence supporting the claims of the authors is solid, although antibody effectiveness as a prophylactic or therapeutic reagent in an animal model would have strengthened the study. The work will be of interest to biologists working to develop pan-coronavirus therapies.

Reviewed by eLife, ScreenIT

Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein

1. Pete Heinzelman
2. Philip A. Romero

Reviewed by ScreenIT

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

1. Kanchan Devkota
2. Matthieu Schapira
3. Sumera Perveen
4. Aliakbar Khalili Yazdi
5. Fengling Li
6. Irene Chau
7. Pegah Ghiabi
8. Taraneh Hajian
9. Peter Loppnau
10. Albina Bolotokova
11. Karla J.F. Satchell
12. Ke Wang
13. Deyao Li
14. Jing Liu
15. David Smil
16. Minkui Luo
17. Jian Jin
18. Paul V. Fish
19. Peter J. Brown
20. Masoud Vedadi

Reviewed by ScreenIT

Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model

1. Denicar Lina Nascimento Fabris Maeda
2. Debin Tian
3. Hanna Yu
4. Nakul Dar
5. Vignesh Rajasekaran
6. Sarah Meng
7. Hassan M. Mahsoub
8. Harini Sooryanarain
9. Bo Wang
10. C. Lynn Heffron
11. Anna Hassebroek
12. Tanya LeRoith
13. Xiang-Jin Meng
14. Steven L. Zeichner

Reviewed by ScreenIT

Randomized trials - Ivermectin repurposing for COVID-19 treatment of outpatients with mild disease in primary health care centers

1. Rossana Elena Chahla
2. Luis Medina Ruiz
3. Teresa Mena
4. Yolanda Brepe
5. Paola Terranova
6. Eugenia Silvana Ortega
7. Guillermo Gabriel Barrenechea
8. Daniel Gustavo Goroso
9. María de los Ángeles Peral de Bruno

Reviewed by ScreenIT

Reanalysis of the Pfizer mRNA BNT162b2 SARS-CoV-2 vaccine data fails to find any increased efficacy following the boost: Implications for vaccination policy and our understanding of the mode of action

1. Allan Saul
2. Heidi E. Drummer
3. Nick Scott
4. Tim Spelman
5. Brendan S. Crabb
6. Margaret Hellard

Reviewed by ScreenIT

Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients

1. Benedetta Sposito
2. Achille Broggi
3. Laura Pandolfi
4. Stefania Crotta
5. Roberto Ferrarese
6. Sofia Sisti
7. Nicola Clementi
8. Alessandro Ambrosi
9. Enju Liu
10. Vanessa Frangipane
11. Laura Saracino
12. Laura Marongiu
13. Fabio A Facchini
14. Andrea Bottazzi
15. Tommaso Fossali
16. Riccardo Colombo
17. Massimo Clementi
18. Elena Tagliabue
19. Antonio E Pontiroli
20. Federica Meloni
21. Andreas Wack
22. Nicasio Mancini
23. Ivan Zanoni

Reviewed by ScreenIT

Secondary attack rates of COVID-19 in Norwegian families: a nation-wide register-based study

1. Kjetil Telle
2. Silje B. Jørgensen
3. Rannveig Hart
4. Margrethe Greve-Isdahl
5. Oliver Kacelnik

Reviewed by ScreenIT

GUIdEStaR (G-quadruplex, uORF, IRES, Epigenetics, Small RNA, Repeats), the integrated metadatabase in conjunction with neural network methods

1. Jee Eun Kang

Reviewed by ScreenIT

Low Dose Regimens of BNT162b2 mRNA Vaccine Exceed SARS-Cov-2 Correlate of Protection Estimates for Symptomatic Infection, in those 19-55 Years of Age

1. Graham Jurgens

Reviewed by ScreenIT

COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

1. Julio S. Solís Arce
2. Shana S. Warren
3. Niccolò F. Meriggi
4. Alexandra Scacco
5. Nina McMurry
6. Maarten Voors
7. Georgiy Syunyaev
8. Amyn Abdul Malik
9. Samya Aboutajdine
10. Opeyemi Adeojo
11. Deborah Anigo
12. Alex Armand
13. Saher Asad
14. Martin Atyera
15. Britta Augsburg
16. Manisha Awasthi
17. Gloria Eden Ayesiga
18. Antonella Bancalari
19. Martina Björkman Nyqvist
20. Ekaterina Borisova
21. Constantin Manuel Bosancianu
22. Magarita Rosa Cabra García
23. Ali Cheema
24. Elliott Collins
25. Filippo Cuccaro
26. Ahsan Zia Farooqi
27. Tatheer Fatima
28. Mattia Fracchia
29. Mery Len Galindo Soria
30. Andrea Guariso
31. Ali Hasanain
32. Sofía Jaramillo
33. Sellu Kallon
34. Anthony Kamwesigye
35. Arjun Kharel
36. Sarah Kreps
37. Madison Levine
38. Rebecca Littman
39. Mohammad Malik
40. Gisele Manirabaruta
41. Jean Léodomir Habarimana Mfura
42. Fatoma Momoh
43. Alberto Mucauque
44. Imamo Mussa
45. Jean Aime Nsabimana
46. Isaac Obara
47. María Juliana Otálora
48. Béchir Wendemi Ouédraogo
49. Touba Bakary Pare
50. Melina R. Platas
51. Laura Polanco
52. Javaeria Ashraf Qureshi
53. Mariam Raheem
54. Vasudha Ramakrishna
55. Ismail Rendrá
56. Taimur Shah
57. Sarene Eyla Shaked
58. Jacob N. Shapiro
59. Jakob Svensson
60. Ahsan Tariq
61. Achille Mignondo Tchibozo
62. Hamid Ali Tiwana
63. Bhartendu Trivedi
64. Corey Vernot
65. Pedro C. Vicente
66. Laurin B. Weissinger
67. Basit Zafar
68. Baobao Zhang
69. Dean Karlan
70. Michael Callen
71. Matthieu Teachout
72. Macartan Humphreys
73. Ahmed Mushfiq Mobarak
74. Saad B. Omer

Reviewed by ScreenIT

Understanding and addressing vaccine hesitancy in the context of COVID-19: development of a digital intervention

1. H. Knight
2. R. Jia
3. K. Ayling
4. K. Bradbury
5. K. Baker
6. T. Chalder
7. J.R. Morling
8. L. Durrant
9. T. Avery
10. J.K. Ball
11. C. Barker
12. R. Bennett
13. T. McKeever
14. K. Vedhara

Reviewed by ScreenIT

Antibody-dependent enhancement (ADE) of SARS-CoV-2 infection in recovered COVID-19 patients: studies based on cellular and structural biology analysis

1. Fan Wu
2. Renhong Yan
3. Mei Liu
4. Zezhong Liu
5. Yingdan Wang
6. Die Luan
7. Kaiyue Wu
8. Zhigang Song
9. Tingting Sun
10. Yunping Ma
11. Yuanyuan Zhang
12. Qimin Wang
13. Xiang Li
14. Ping Ji
15. Yaning Li
16. Cheng Li
17. Yanling Wu
18. Tianlei Ying
19. Yumei Wen
20. Shibo Jiang
21. Tongyu Zhu
22. Lu Lu
23. Yongzhen Zhang
24. Qiang Zhou
25. Jinghe Huang

Reviewed by ScreenIT

Effectiveness of portable air filtration on reducing indoor aerosol transmission: preclinical observational trials

1. J.H. Lee
2. M. Rounds
3. F. McGain
4. R. Schofield
5. G. Skidmore
6. I. Wadlow
7. K. Kevin
8. A. Stevens
9. C. Marshall
10. L. Irving
11. M. Kainer
12. K. Buising
13. J. Monty

Reviewed by ScreenIT

A rigorous framework for detecting SARS-CoV-2 spike protein mutational ensemble from genomic and structural features

1. Saman Fatihi
2. Surabhi Rathore
3. Ankit K. Pathak
4. Deepanshi Gahlot
5. Mitali Mukerji
6. Nidhi Jatana
7. Lipi Thukral

Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

Comparing the efficacy of anti□infectious drugs for the treatment of mild to severe COVID-19 patients: a protocol for a systematic review and network meta-analysis of randomized clinical trials

1. Dejene Tolossa Debela
2. Kidist Digamo Heraro

Reviewed by ScreenIT

Design and proof of concept for targeted phage-based COVID-19 vaccination strategies with a streamlined cold-free supply chain

1. Daniela I. Staquicini
2. Fenny H. F. Tang
3. Christopher Markosian
4. Virginia J. Yao
5. Fernanda I. Staquicini
6. Esteban Dodero-Rojas
7. Vinícius G. Contessoto
8. Deodate Davis
9. Paul O’Brien
10. Nazia Habib
11. Tracey L. Smith
12. Natalie Bruiners
13. Richard L. Sidman
14. Maria L. Gennaro
15. Edmund C. Lattime
16. Steven K. Libutti
17. Paul C. Whitford
18. Stephen K. Burley
19. José N. Onuchic
20. Wadih Arap
21. Renata Pasqualini

Reviewed by ScreenIT

Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V and SARS-CoV-2 Spike glycoproteins

1. George Lagoumintzis
2. Christos T. Chasapis
3. Nikolaos Alexandris
4. Dimitrios Kouretas
5. Socrates Tzartos
6. Elias Eliopoulos
7. Konstantinos Farsalinos
8. Konstantinos Poulas

Reviewed by ScreenIT

Testing and vaccination to reduce the impact of COVID-19 in nursing homes: an agent-based approach

1. José P. Gómez Vázquez
2. Yury E. García
3. Alec J. Schmidt
4. Beatriz Martínez-López
5. Miriam Nuño

Reviewed by ScreenIT

Mechanistic theory predicts the effects of temperature and humidity on inactivation of SARS-CoV-2 and other enveloped viruses

1. Dylan H Morris
2. Kwe Claude Yinda
3. Amandine Gamble
4. Fernando W Rossine
5. Qishen Huang
6. Trenton Bushmaker
7. Robert J Fischer
8. M Jeremiah Matson
9. Neeltje Van Doremalen
10. Peter J Vikesland
11. Linsey C Marr
12. Vincent J Munster
13. James O Lloyd-Smith

Reviewed by ScreenIT