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A list by Prachee Avasthi Recommended Reading

See what researchers at Prachee Avasthi’s lab are reading to discover some interesting new work.

193 articlesLast updated

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  6. Single-cell transcriptomics for the 99.9% of species without reference genomes

    1. Olga Borisovna Botvinnik
    2. Venkata Naga Pranathi Vemuri
    3. N. Tessa Pierce
    4. Phoenix Aja Logan
    5. Saba Nafees
    6. Lekha Karanam
    7. Kyle Joseph Travaglini
    8. Camille Sophie Ezran
    9. Lili Ren
    10. Yanyi Juang
    11. Jianwei Wang
    12. Jianbin Wang
    13. C. Titus Brown
    Appears in 1 listLatest version

  7. A ciliopathy complex builds distal appendages to initiate ciliogenesis

    1. Dhivya Kumar
    2. Addison Rains
    3. Vicente Herranz-Pérez
    4. Quanlong Lu
    5. Xiaoyu Shi
    6. Danielle L. Swaney
    7. Erica Stevenson
    8. Nevan J. Krogan
    9. Bo Huang
    10. Christopher Westlake
    11. Jose Manuel Garcia-Verdugo
    12. Bradley K. Yoder
    13. Jeremy F. Reiter

    Reviewed by preLights

    1 evaluationAppears in 2 listsLatest version Latest activity

  9. A novel live-cell imaging assay reveals regulation of endosome maturation

    1. Maria Podinovskaia
    2. Cristina Prescianotto-Baschong
    3. Dominik P Buser
    4. Anne Spang

    • Curated by eLife

      Evaluation Summary:

      Endosome maturation in animal cells has been challenging to characterize by microscopy because the fluorescence patterns are complex and dynamic. This study uses acute ionophore treatment to generate enlarged early endosomes, whose behavior and maturation can then be readily tracked. The results offer new insights into several phenomena, including the regulation of endosomal acidification during the maturation process.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 and Reviewer #3 agreed to share their names with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 3 listsLatest version Latest activity

  17. The molecular mechanism of load adaptation by branched actin networks

    1. Tai-De Li
    2. Peter Bieling
    3. Julian Weichsel
    4. R Dyche Mullins
    5. Daniel A Fletcher

    • Curated by eLife

      Evaluation Summary:

      This in vitro study proposes to explain why branched actin filament networks, similar to the ones encountered in migrating cells, become denser when they grow against a mechanical load. This question is of broad interest, and has long been waiting for a molecular-scale explanation. Building on their previously published tools and results, the authors perform a series of elegant and clever experiments, and convincingly identify key molecular mechanisms. Importantly, the results also confirm the Brownian ratchet model for actin assembly. This study captures several important features of branched filament networks, and should become a reference on the topic.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 2 listsLatest version Latest activity
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