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A list by Prachee Avasthi Recommended Reading

See what researchers at Prachee Avasthi’s lab are reading to discover some interesting new work.

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  1. Clathrin coats partially preassemble and subsequently bend during endocytosis

    1. Markus Mund
    2. Aline Tschanz
    3. Yu-Le Wu
    4. Felix Frey
    5. Johanna L. Mehl
    6. Marko Kaksonen
    7. Ori Avinoam
    8. Ulrich S. Schwarz
    9. Jonas Ries

    Reviewed by Review Commons

    4 evaluationsAppears in 2 listsLatest version Latest activity

    Prachee Avasthi Recommended Reading

    This is an incredible study using super resolution imaging and mathematical modeling to propose a new model of clathrin coat assembly (the cooperative curvature model) that challenges both the constant curvature and constant area (flat membrane preassembly of clathrin) assembly models.

  2. Pericentrin is a Kinesin-1 Activator that Drives Centriole Motility

    1. Matthew R. Hannaford
    2. Rong Liu
    3. Neil Billington
    4. Zachary T. Swider
    5. Brian J. Galletta
    6. Carey J. Fagerstrom
    7. Christian Combs
    8. James R. Sellers
    9. Nasser M. Rusan
    Appears in 1 listLatest version

    Prachee Avasthi Recommended Reading

    Important study showing centriole migration of mother centrioles in fly neuroblasts during interphase is mediated by kinesin-1 (as cargo) and pericentrin-like protein. The actin cytoskeleton has been implicated in this but is not responsible in this context.

  3. Proteomic Dissection of a Giant Cell

    1. Athena Lin
    2. Paul D. Piehowski
    3. Chia-Feng Tsai
    4. Tatyana Makushok
    5. Lian Yi
    6. Ulises Diaz
    7. Connie Yan
    8. Diana Summers
    9. Pranidhi Sood
    10. Richard D. Smith
    11. Tao Liu
    12. Wallace F. Marshall
    Appears in 1 listLatest version

  8. Islet primary cilia motility controls insulin secretion

    1. Jung Hoon Cho
    2. Zipeng A. Li
    3. Lifei Zhu
    4. Brian D. Muegge
    5. Henry F. Roseman
    6. Eun Young Lee
    7. Toby Utterback
    8. Louis G. Woodhams
    9. Philip V. Bayly
    10. Jing W. Hughes
    Appears in 1 listLatest version

  10. Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions

    1. Eden Yifrach
    2. Duncan Holbrook‐Smith
    3. Jérôme Bürgi
    4. Alaa Othman
    5. Miriam Eisenstein
    6. Carlo WT van Roermund
    7. Wouter Visser
    8. Asa Tirosh
    9. Markus Rudowitz
    10. Chen Bibi
    11. Shahar Galor
    12. Uri Weill
    13. Amir Fadel
    14. Yoav Peleg
    15. Ralf Erdmann
    16. Hans R Waterham
    17. Ronald J A Wanders
    18. Matthias Wilmanns
    19. Nicola Zamboni
    20. Maya Schuldiner
    21. Einat Zalckvar
    Appears in 1 listLatest version

  12. On demand expression control of endogenous genes with DExCon, DExogron and LUXon reveals differential dynamics of Rab11 family members

    1. Jakub Gemperle
    2. Thomas S Harrison
    3. Chloe Flett
    4. Antony D Adamson
    5. Patrick T Caswell

    • Curated by eLife

      Evaluation Summary:

      This work reports a genome editing strategy that enables blocking and tetracycline-controlled re-expression of fluorescently-tagged proteins from endogenous loci. The authors combine this with the photoactivatable tet-on/off system, a knocksideways approach, as well as the auxin-inducible degron system to improve spatial and temporal control of gene expression. They demonstrate the applicability of the methods by studying the localization, function and protein-expression dynamics of the Rab11-family of small GTPases. Using these approaches, the authors discover subtle differences in the localization as well as expression and degradation kinetics of Rab11a/b/Rab25. The work will be of broad interest to molecular and cell biologists.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 2 listsLatest version Latest activity

  13. Load adaptation of endocytic actin networks

    1. Charlotte Kaplan
    2. Sam J. Kenny
    3. Xuyan Chen
    4. Johannes Schöneberg
    5. Ewa Sitarska
    6. Alba Diz-Muñoz
    7. Matthew Akamatsu
    8. Ke Xu
    9. David G. Drubin

    Reviewed by ASAPbio crowd review

    1 evaluationAppears in 2 listsLatest version Latest activity

  16. The phenotypic landscape of essential human genes

    1. Luke Funk
    2. Kuan-Chung Su
    3. Jimmy Ly
    4. David Feldman
    5. Avtar Singh
    6. Brittania Moodie
    7. Paul C. Blainey
    8. Iain M. Cheeseman
    Appears in 1 listLatest version
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