@rdshrestha's saved articles

Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons

1. Wei Liu
2. Rupendra Shrestha
3. Albert Lowe
4. Xusheng Zhang
5. Ludovic Spaeth

• Curated by eLife

  eLife assessment

  In this important study, the authors present a human telencephalon-eye organoid model that exhibits remarkable pathfinding and growth of retinal ganglion cell (RGC) axons. The identification of cell-surface markers for RGCs could have value for understanding the molecular mechanisms involved in RGC axon development and regeneration. The strength of evidence is compelling for future studies to investigate RGC neurite outgrowth and brain-eye connectivity in humans.

Reviewed by eLife

Six3 and Six6 jointly regulate the identities and developmental trajectories of multipotent retinal progenitor cells in the mouse retina

1. Alexander Ferrena
2. Xusheng Zhang
3. Rupendra Shrestha
4. Deyou Zheng
5. Wei Liu