Showing page 1 of 1 pages of list content

  1. Self-formation of concentric zones of telencephalic and ocular tissues and directional retinal ganglion cell axons

    This article has 5 authors:
    1. Wei Liu
    2. Rupendra Shrestha
    3. Albert Lowe
    4. Xusheng Zhang
    5. Ludovic Spaeth
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      In this important study, the authors present a human telencephalon-eye organoid model that exhibits remarkable pathfinding and growth of retinal ganglion cell (RGC) axons. The identification of cell-surface markers for RGCs could have value for understanding the molecular mechanisms involved in RGC axon development and regeneration. The strength of evidence is compelling for future studies to investigate RGC neurite outgrowth and brain-eye connectivity in humans.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 3 listsLatest version Latest activity