Showing page 3 of 32 pages of list content

  1. Acquisition of an immunosuppressive microenvironment after CAR-T therapy drives T-cell dysfunction and resistance

    This article has 23 authors:
    1. Marianna Ponzo
    2. Lorenzo Drufuca
    3. Chiara Buracchi
    4. Marco M. Sindoni
    5. Silvia Nucera
    6. Cristina Bugarin
    7. Ramona Bason
    8. Grazisa Rossetti
    9. Raoul Bonnal
    10. Cristian Meli
    11. Benedetta Rambaldi
    12. Federico Lussana
    13. Silvia Ferrari
    14. Alex Moretti
    15. Giulia Risca
    16. Christian Pellegrino
    17. Markus G. Manz
    18. Stefania Galimberti
    19. Alessandro Rambaldi
    20. Giuseppe Gaipa
    21. Andrea Biondi
    22. Massimiliano Pagani
    23. Chiara F. Magnani

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Small molecule modulator of neuronal lysosome positioning and function resolves Alzheimer’s Disease-linked pathologies in cultured human neurons

    This article has 14 authors:
    1. Amanda M. Snead
    2. Sruchi Patel
    3. Mia Krout
    4. Ryan S. Hippman
    5. Gabrielle Smith
    6. Diya Dileep
    7. Nitya Chagoor
    8. Rachel Shi
    9. Ricardo Linares
    10. Andrew Dobria
    11. Stephanie M. Cologna
    12. Camerron Crowder
    13. Leslie N. Aldrich
    14. Swetha Gowrishankar

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  3. Maintenance of neuronal TDP-43 expression requires axonal lysosome transport

    This article has 18 authors:
    1. Veronica H Ryan
    2. Sydney Lawton
    3. Joel F Reyes
    4. James Hawrot
    5. Ashley M Frankenfield
    6. Sahba Seddighi
    7. Daniel M Ramos
    8. Faraz Faghri
    9. Nicholas L Johnson
    10. Jizhong Zou
    11. Martin Kampmann
    12. John Replogle
    13. Hebao Yuan
    14. Kory R Johnson
    15. Dragan Maric
    16. Ling Hao
    17. Mike A Nalls
    18. Michael E Ward
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      In this important manuscript, Ryan et al perform a genome-wide CRISPR based screen to identify genes that modulate TDP-43 levels in neurons. They identify a number of genes and pathways and highlight the BORC complex, which is required for anterograde lysosome transport as one such regulator of TDP-43 protein levels. Overall, this is a convincing study, which opens the door for additional future investigations on the regulation of TDP-43.

    Reviewed by PREreview, eLife

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  4. Safety and Efficacy of Chimeric Antigen Receptor T-cell Therapy for Recurrent Glioblastoma: An Augmented Meta-analysis of Phase 1 Clinical Trials

    This article has 14 authors:
    1. Ahmed Y. Azzam
    2. Mahmoud M. Morsy
    3. Mohammed A. Azab
    4. Osman Elamin
    5. Adam Elswedy
    6. Omar S. Ahmed
    7. Mahmoud Nassar
    8. Ahmed Saad Al Zomia
    9. Adham A. Mohamed
    10. Oday Atallah
    11. Ahmed Alamoud
    12. Hammam A. Alotaibi
    13. Hana J. Abukhadijah
    14. Abdulqadir J Nashwan

    Reviewed by PREreview

    This article has 1 evaluationAppears in 1 listLatest version Latest activity