Reading List

Computational design of BclxL inhibitors that target transmembrane domain interactions

1. Gerard Duart
2. Assaf Elazar
3. Jonathan Y. Weinstein
4. Laura Gadea-Salom
5. Juan Ortiz-Mateu
6. Sarel J. Fleishman
7. Ismael Mingarro
8. Luis Martinez-Gil

Emergence of ion-channel-mediated electrical oscillations in Escherichia coli biofilms

1. Emmanuel Akabuogu
2. Victor Carneiro da Cunha Martorelli
3. Rok Krašovec
4. Ian S Roberts
5. Thomas A Waigh

• Curated by eLife

  eLife Assessment

  This potentially valuable study presents claims of evidence for coordinated membrane potential oscillations in E. coli biofilms that can be linked to a putative K+ channel and that may serve to enhance photo-protection. The finding of waves of membrane potential would be of interest to a wide audience from molecular biology to microbiology and physical biology. Unfortunately, a major issue is that it is unclear whether the dye used can act as a Nernstian membrane potential dye in E. coli. The arguments of the authors, who largely ignore previously published contradictory evidence, are not adequate in that they do not engage with the fact that the dye behaves in their hands differently than in the hands of others. In addition, the lack of proper validation of the experimental method including key control experiments leaves the evidence incomplete.

Reviewed by eLife

Lysosomal calcium loading promotes arrhythmias by potentiating ryanodine receptor release

1. Zhaozheng Meng
2. Rebecca A Capel
3. Samuel J Bose
4. Erik Bosch
5. Sophia de Jong
6. Robert Planque
7. Antony Galione
8. Rebecca AB Burton
9. Alfonso Bueno-Orovio

Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases

1. Jannik Strauss
2. Craig Wilkinson
3. Keni Vidilaseris
4. Orquidea M de Castro Ribeiro
5. Jianing Liu
6. James Hillier
7. Maximilian Wichert
8. Anssi M Malinen
9. Bernadette Gehl
10. Lars JC Jeuken
11. Arwen R Pearson
12. Adrian Goldman

Dynamics of Mitochondrial NAD ⁺ Import Reveal Preference for Oxidized Ligand and Substrate Led Transport

1. Shivansh Goyal
2. Xiaolu A. Cambronne

Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel

1. Rafael Ramis
2. Óscar R. Ballesteros
3. Arantza Muguruza-Montero
4. Sara M-Alicante
5. Eider Núñez
6. Álvaro Villarroel
7. Aritz Leonardo
8. Aitor Bergara

A new polymodal gating model of the proton-activated chloride channel

1. Piao Zhao
2. Cheng Tang
3. Yuqin Yang
4. Zhen Xiao
5. Samantha Perez-Miller
6. Heng Zhang
7. Guoqing Luo
8. Hao Liu
9. Yaqi Li
10. Qingyi Liao
11. Fan Yang
12. Hao Dong
13. Rajesh Khanna
14. Zhonghua Liu

Structural basis for ion selectivity in potassium-selective channelrhodopsins

1. Seiya Tajima
2. Yoon Seok Kim
3. Masahiro Fukuda
4. YoungJu Jo
5. Peter Y. Wang
6. Joseph M. Paggi
7. Masatoshi Inoue
8. Eamon F.X. Byrne
9. Koichiro E. Kishi
10. Seiwa Nakamura
11. Charu Ramakrishnan
12. Shunki Takaramoto
13. Takashi Nagata
14. Masae Konno
15. Masahiro Sugiura
16. Kota Katayama
17. Toshiki E. Matsui
18. Keitaro Yamashita
19. Suhyang Kim
20. Hisako Ikeda
21. Jaeah Kim
22. Hideki Kandori
23. Ron O. Dror
24. Keiichi Inoue
25. Karl Deisseroth
26. Hideaki E. Kato

A Hydrophobic Microenvironment Significantly Influences the Reactivity of the Catalytically Relevant Thiols of the Na ⁺ /K ⁺ -ATPase

1. Titilayo Ibironke Ologunagba
2. Tolulope Ayoola Ojo
3. Ige Joseph Kade

Cross-Linking of Catalytically Essential Vicinal Thiols at Active Sites of the Cerebral Sodium Transporter Inactivates its Electrogenic Function

1. Titilayo Ibironke Ologunagba
2. Bunmi Olaoluwa Olorundare
3. Ige Joseph Kade

The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Nav1.5

1. Oksana Iamshanova
2. Anne-Flore Hämmerli
3. Elise Ramaye
4. Arbresh Seljmani
5. Daniela Ross-Kaschitza
6. Noëlia Schärz
7. Maria Essers
8. Sabrina Guichard
9. Jean-Sébastien Rougier
10. Hugues Abriel

Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9

1. Louise Gerard
2. Laurent Duvivier
3. Marie Fourrez
4. Paula Salazar
5. Lindsay Sprimont
6. Di Xia
7. Suresh V. Ambudkar
8. Michael M. Gottesman
9. Jean-Pierre Gillet

Structural basis of V-ATPase V _O region assembly by Vma12p, 21p, and 22p

1. Hanlin Wang
2. Stephanie A. Bueler
3. John L. Rubinstein

Atomistic Insights Into The Mechanism of Dual Affinity Switching In Plant Nitrate Transporter NRT1.1

1. Balaji Selvam
2. Jiangyan Feng
3. Diwakar Shukla

Structure of human TRPM8 channel

1. Sergii Palchevskyi
2. Mariusz Czarnocki-Cieciura
3. Giulio Vistoli
4. Silvia Gervasoni
5. Elżbieta Nowak
6. Andrea R. Beccari
7. Marcin Nowotny
8. Carmine Talarico

Structure of a G protein-coupled receptor with GRK2 and a biased ligand

1. Jia Duan
2. Heng Liu
3. Yujie Ji
4. Qingning Yuan
5. Xinzhu Li
6. Kai Wu
7. Tianyu Gao
8. Shengnan Zhu
9. Wanchao Yin
10. Yi Jiang
11. H. Eric Xu

On the Ca2＋ elevation in vascular endothelial cells due to inositol trisphosphate-sensitive store receptors activation: A data-driven modeling approach

1. Alberto Coccarelli
2. Sanjay Pant

A Vaccinia-based system for directed evolution of GPCRs in mammalian cells

1. Christoph Klenk
2. Maria Scrivens
3. Anina Niederer
4. Shuying Shi
5. Loretta Mueller
6. Elaine Gersz
7. Maurice Zauderer
8. Ernest S. Smith
9. Ralf Strohner
10. Andreas Plückthun

Phospholipids are imported into mitochondria by VDAC, a dimeric beta barrel scramblase

1. Helene Jahn
2. Ladislav Bartoš
3. Grace I. Dearden
4. Jeremy S. Dittman
5. Joost C. M. Holthuis
6. Robert Vácha
7. Anant K. Menon

Elucidation of Global Trends in the Effects of VX-661 and VX-445 on the Expression of Clinical CFTR Variants

1. Andrew G. McKee
2. Eli F. McDonald
3. Wesley D. Penn
4. Charles P. Kuntz
5. Karen Noguera
6. Laura M. Chamness
7. Francis J. Roushar
8. Jens Meiler
9. Kathryn E. Oliver
10. Lars Plate
11. Jonathan P. Schlebach