Reading List

Steric control of signaling bias in the immunometabolic receptor GPR84

1. Pinqi Wang
2. Xuan Zhang
3. Akim-Abdul Guseinov
4. Laura Jenkins
5. Carl von Hallerstein
6. Jonathan D Colburn
7. Rowan Ives
8. Vincent B Luscombe
9. Sara Marsango
10. Listiana Oktavia
11. Arun Raja
12. David R Greaves
13. Philip C Biggin
14. Graeme Milligan
15. Cheng Zhang
16. Irina Tikhonova
17. Angela J Russell

Subunit-specific roles of LRRC8 proteins in determining glutamate permeability of astrocytic volume-regulated anion channels

1. Madison L. Chandler
2. Ariella D. Sprague
3. Julia W. Nalwalk
4. Alexander A. Mongin

Structural determinants for GqPCR-mediated inhibition of TASK K2P K ⁺ channels and their dysfunction in disease

1. Thibault R. H. Jouen-Tachoire
2. Peter Proks
3. David Seiferth
4. Kate Crowther
5. Philip C. Biggin
6. Thomas Baukrowitz
7. Marcus Schewe
8. Stephen J. Tucker

Mitochondria-Targeted Peptides and Bilayer Composition Modulate Membrane Electroporation Under Elevated Electrochemical Stress

1. Jeffrey D. Tamucci
2. Adam Zweifach
3. Nathan N. Alder
4. Eric R. May

Allostery between distant structural regions dictates selectivity in GPCR:G protein coupling

1. Elizaveta Mukhaleva
2. Edgardo J. Sánchez Rivas
3. Sergio Branciamore
4. Andrei S. Rodin
5. Sivaraj Sivaramakrishnan
6. Nagarajan Vaidehi

Lipid Dynamics and Organization Around Voltage-Gated Sodium Channels: A Coarse-Grained Perspective

1. Abhinav Srivastava
2. Paweł Chodnicki
3. Jacek Czub
4. Vincenzo Carnevale

D-serine suppresses one-carbon metabolism by competing with mitochondrial L-serine transport

1. Masataka Suzuki
2. Kenichiro Adachi
3. Pattama Wiriyasermukul
4. Mariko Fukumura
5. Ryota Tamura
6. Yoshinori Hirano
7. Yumi Aizawa
8. Tetsuya Miyamoto
9. Sakiko Taniguchi
10. Masahiro Toda
11. Hiroshi Homma
12. Kohsuke Kanekura
13. Kenji Yasuoka
14. Takanori Kanai
15. Masahiro Sugimoto
16. Shushi Nagamori
17. Masato Yasui
18. Jumpei Sasabe

• Curated by eLife

  eLife Assessment

  This work presents valuable new data on the role of D-Serine and how it competes with its stereoisomer L-Serine to influence metabolism. The work presents a variety of solid experimental data combined with simulated results to investigate the mechanisms focused on one-carbon metabolism, which is relevant for several research fields. However, some claims are only partially supported by data, and critical areas comparing L- vs D-Serine and further mechanistic studies are incomplete. Furthermore, while the work has potential for various fields, the work has only been studied in a limited cell type and context.

Reviewed by eLife

Structural and dynamic insights into phosphate uptake by PHT1 transporter in rice

1. Zhangmeng Du
2. Zeyuan Guan
3. Hai Liu
4. Jie Zhang
5. Haitao He
6. Zhiwen Zheng
7. Wenhui Zhang
8. Lihuan Jiang
9. Jiaqi Zuo
10. Yan Liu
11. Beijing Wan
12. Haifu Tu
13. Faming Dong
14. Xuelei Lai
15. Lizhong Xiong
16. Ping Yin
17. Shaowu Xue
18. Yanke Chen
19. Zhu Liu

Membrane Transport of Rhodamine 6G by the reconstituted multidrug resistance–ABC transporter Pdr5 in Horizontal Lipid Bilayer

1. Daniel Blum
2. Lea-Marie Nentwig
3. Stefanie L. Gala Marti
4. Lutz Schmitt
5. Richard Wagner

An Allosteric Model for Electromechanical Coupling in Cardiac CNBD Channels

1. Gucan Dai

Molecular determinants of selective and high-affinity binding of the scaffold protein PDZK1 to the transporter URAT1

1. E.V. Mymrikov
2. C. Wirth
3. J.I. Heinicke
4. J. Goll
5. B.A. Kern
6. C. Steck
7. A.K. Iaroslavtceva
8. T. Mühlethaler
9. A. Köttgen
10. C. Hunte

Influence of Substrate on Supported Lipid Bilayers: Membrane Pinning, Stretching, Pores, and Remodelling

1. Rafael B. Lira
2. Wouter H. Roos

Active Conformations of Neuronal Na ⁺ ,K ⁺ -ATPase isoforms and a Disease-Causing Mutant

1. Mads Eskesen Christensen
2. Michael Habeck
3. Adriana Katz
4. Marlene Uglebjerg Fruergaard
5. Yoav Peleg
6. Uri Pick
7. Steven J D Karlish
8. Poul Nissen

Membrane Permeability Drives the Extreme Potency of Fentanyl but not Isotonitazene

1. Joseph Clayton
2. George J. Farmer
3. Jacqueline Glenn
4. Shailesh N. Mistry
5. J. Robert Lane
6. Lei Shi
7. Lidiya Stavitskaya
8. Meritxell Canals
9. Jana Shen

Importance of cysteines for the binding of S100A6 to the RAGE receptor – Towards a first molecular model for S100 covalent dimerization

1. Maria Demou
2. Laure Yatime

TMEM63 proteins act as mechanically activated cholesterol modulated lipid scramblases contributing to membrane mechano-resilience

1. Yiechang Lin
2. Zijing Zhou
3. Yaoyao Han
4. Delfine Cheng
5. Haoqing Wang
6. Arnold Lining Ju
7. Yixiao Zhang
8. Charles D Cox
9. Ben Corry

A LARGE-SCALE EVOLUTIONARY AND STRUCTURAL ANALYSIS OF CLC CHANNELS AND TRANSPORTERS

1. Ayush Mishra
2. Gladys Díaz Vázquez
3. Janice L. Robertson

Mechanism and Structure-Guided Optimization of SLC1A1/EAAT3-Selective Inhibitors in Kidney Cancer

1. Pooneh Koochaki
2. Biao Qiu
3. Jesse A. Coker
4. Alexander Earsley
5. Nancy S. Wang
6. Todd Romigh
7. Christopher M. Goins
8. Shaun R. Stauffer
9. Olga Boudker
10. Abhishek A. Chakraborty

UBE2J2 sensitizes the ERAD ubiquitination cascade to changes in membrane lipid saturation

1. Aikaterini Vrentzou
2. Florian Leidner
3. Claudia C. Schmidt
4. Helmut Grubmüller
5. Alexander Stein

Integrative structural analysis of the human endosomal Na⁺/H⁺ exchanger NHE6 reveals a lipid-stabilized intracellular gate and a disordered C-terminus

1. Lukas Peter Feilen
2. Emil Enshelm Tranchant
3. Milena Rankilde Lilac
4. Lara Kristin Sach
5. Jesper Havelund
6. Jan Ostendorf
7. Nils J Faergeman
8. Stine Falsig Pedersen
9. Birthe B. Kragelund
10. Henriette Autzen