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Structural and dynamic studies uncover a distinct allosteric modulatory site at the μ-opioid receptor

This article has 11 authors:
1. Haonan Zhang
2. Kirill Konovalov
3. Alexandra K. Parpounas
4. Davide Provasi
5. Shifan Yang
6. Alejandro Abraham
7. Audrey L. Warren
8. Gregory Zilberg
9. Suri Wang
10. Marta Filizola
11. Daniel Wacker
This article has no evaluationsAppears in 1 listLatest version Oct 15, 2025
Lipid composition and mechanical force underlie multi-modal regulation of Piezo1 gating

This article has 2 authors:
1. George Vaisey
2. Roderick MacKinnon
This article has no evaluationsAppears in 1 listLatest version Oct 25, 2025
Interrogating the structure and function of the human voltage-gated proton channel (hH _v 1) with a fluorescent noncanonical amino acid

This article has 3 authors:
1. Emerson M. Carmona
2. William N. Zagotta
3. Sharona E. Gordon
This article has no evaluationsAppears in 1 listLatest version Oct 24, 2025
Selectivity Filter Dynamics Define Ion Conductance and Selectivity Differences in CNG and HCN Channels

This article has 4 authors:
1. Haoran Liu
2. Klaus Benndorf
3. Yessenbek K. Aldakul
4. Han Sun
This article has no evaluationsAppears in 1 listLatest version Oct 23, 2025
A biased allosteric modulator functions as a molecular glue to induce β ₂ AR dimerization

This article has 10 authors:
1. Jiemin Shen
2. Teja Nikhil Peddada
3. Konstantin E. Komolov
4. Francesco De Pascali
5. Alexander M. Garces
6. Haoqing Wang
7. Michael T. Lerch
8. Jeffrey L. Benovic
9. Jun Xu
10. Brian K. Kobilka
This article has no evaluationsAppears in 1 listLatest version Oct 22, 2025
Cryo-EM Structures of Methanogenic Schizorhodopsins Reveal Divergent Strategies for Proton Transport and Thermal Adaptation

This article has 10 authors:
1. Iota Ebisu
2. Tatsuki Tanaka
3. Yuma Kawasaki
4. Shunya Murakoshi
5. Keisei Shibata
6. Yoshitaka Kato
7. Masae Konno
8. Wataru Shihoya
9. Keiichi Inoue
10. Osamu Nureki
This article has no evaluationsAppears in 1 listLatest version Oct 20, 2025
Autoregulation of the MET Receptor Tyrosine Kinase by its Intracellular Juxtamembrane Domain

This article has 5 authors:
1. Edmond M. Linossi
2. Carla A. Espinoza
3. Gabriella O. Estevam
4. James S. Fraser
5. Natalia Jura
This article has no evaluationsAppears in 1 listLatest version Oct 19, 2025
The bacterial schizorhodopsins: novel light-driven inward proton pumps from Antarctic Minisyncoccota (Patescibacteria) and cyanobacteria, with implications for the proton-pumping mechanism

This article has 5 authors:
1. María del Carmen Marín
2. Masae Konno
3. Andrey Rozenberg
4. Oded Béjà
5. Labinoue Inoue
This article has no evaluationsAppears in 1 listLatest version Oct 16, 2025
Structure based discovery of antipsychotic-like TAAR1 agonists

This article has 14 authors:
1. Sijie Huang
2. Heng Liu
3. Yujin Wu
4. Joao M. Braz
5. Divya Kranthi
6. Brendan W. Hall
7. Xinyue Zhang
8. Dmytro S. Radchenko
9. Yurii S. Moroz
10. John J. Irwin
11. Allan I. Basbaum
12. H. Eric Xu
13. William C. Wetsel
14. Brian K. Shoichet
This article has no evaluationsAppears in 1 listLatest version Oct 16, 2025
A single residue determines regulation of TRPV1 by phosphoinositides

This article has 5 authors:
1. Benjamin He
2. Prateeti Varanasi
3. Nia M. Barkum
4. Rose Hudson
5. Eric N. Senning
This article has no evaluationsAppears in 1 listLatest version Oct 15, 2025
Homeostatic regulation of intrinsic lipid curvature in eukaryotic cells

This article has 7 authors:
1. Daniel Milshteyn
2. Jacob R. Winnikoff
3. Elida Kocharian
4. Aaron M. Armando
5. Edward A. Dennis
6. Peter R. Girguis
7. Itay Budin
This article has no evaluationsAppears in 1 listLatest version Oct 14, 2025
High Throughput Screening Identifies a Small Molecule Trafficking Corrector for Long-QT Syndrome Associated KCNQ1 Variants

This article has 17 authors:
1. Katherine R. Clowes Moster
2. Carlos G. Vanoye
3. Ana C Chang-Gonzalez
4. Ian M. Romaine
5. Katherine M. Stefanski
6. Mason C. Wilkinson
7. Joshua A. Bauer
8. Thomas P. Hasaka
9. Emily L. Days
10. Reshma Desai
11. Kathryn R. Butcher
12. Gary A. Sulikowksi
13. Alex G. Waterson
14. Jens Meiler
15. Kaitlyn Ledwitch
16. Alfred L George
17. Charles R. Sanders
This article has no evaluationsAppears in 1 listLatest version Oct 14, 2025
Asymmetric phosphoinositide lipid bilayers generated by spontaneous lipid insertion

This article has 9 authors:
1. Gwendal Guerin
2. Thi Lan Anh Nguyen
3. John Manzi
4. Christophe Le Clainche
5. Julien Heuvingh
6. Julien Berro
7. Nicolas Rodriguez
8. Sophie Cribier
9. Feng-Ching Tsai
This article has no evaluationsAppears in 1 listLatest version Mar 30, 2025
Structural basis for gating inhibition by the cytoplasmic domain in HCN1 channels

This article has 7 authors:
1. V. Zorzini
2. J.M. Kleiz-Ferreira
3. M. Brams
4. R. Gallardo
5. S. De Gieter
6. J. Kusch
7. C. Ulens
This article has no evaluationsAppears in 1 listLatest version Oct 14, 2025
Clustering of SARS-CoV-2 membrane proteins in lipid bilayer membranes

This article has 8 authors:
1. Joseph McTiernan
2. Yuanzhong Zhang
3. Siyu Li
4. Thomas E. Kuhlman
5. Umar Mohideen
6. Michael E. Colvin
7. Roya Zandi
8. Ajay Gopinathan
This article has no evaluationsAppears in 1 listLatest version Oct 10, 2025
Mechanistic Insights into the Structural Asymmetry of the LanFEG Transporter NisFEG in Lantibiotic Immunity

This article has 4 authors:
1. Pablo A. Cea
2. Julia Gottstein
3. Sander H.J. Smits
4. Holger Gohlke
This article has no evaluationsAppears in 1 listLatest version Oct 10, 2025
Engineering substrate selectivity in the human sodium/iodide symporter (NIS)

This article has 10 authors:
1. Alejandro Llorente-Esteban
2. Haswitha Sabbineni
3. Kendra Hoffsmith
4. Rían W. Manville
5. David López-González
6. Andrea Reyna-Neyra
7. J. Alfonso Leyva
8. Geoffrey W. Abbott
9. Mario A. Bianchet
10. Nancy Carrasco
This article has no evaluationsAppears in 1 listLatest version Oct 8, 2025
Nanobody-Driven Stabilization Synergistically Rescues F508del-CFTR and Reveals an Alternative Active State of the Channel

This article has 14 authors:
1. Marie Overtus
2. Tihomir Rubil
3. James N. Charlick
4. Andrew S. Paige
5. Blaine J. Loughlin
6. Zachary Rich
7. Mayuree Rodrat
8. Zhengrong Yang
9. Anita Balázs
10. John C. Kappes
11. Marcus A. Mall
12. David N. Sheppard
13. John F. Hunt
14. Cédric Govaerts
This article has no evaluationsAppears in 1 listLatest version Oct 8, 2025
Unconventional Fusion Mechanism at the Origin of Eukaryotic Membranes

This article has 3 authors:
1. Maria L. Mascotti
2. Luis S. Mayorga
3. Diego Masone
This article has no evaluationsAppears in 1 listLatest version Oct 7, 2025
A bi-directional binding site linking the α ₂ δ-1 subunit to the intrinsic speed control process in VSD I of voltage-gated calcium channels

This article has 6 authors:
1. Martin C. Heiss
2. Monica L. Fernández-Quintero
3. Nicole Kranbitter
4. Hajar El Aouad
5. Marta Campiglio
6. Bernhard E. Flucher
This article has no evaluationsAppears in 1 listLatest version Oct 7, 2025