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Structural mechanism of lipid modulation of pentameric ligand-gated ion channel activity

This article has 5 authors:
1. Brando K Tan
2. Hanrui Xu
3. Jesse W Sandberg
4. Grace Brannigan
5. Wayland WL Cheng
This article has no evaluationsAppears in 1 listLatest version Oct 7, 2025
Plasma membrane-endoplasmic reticulum coupling probed with genetically-encoded voltage sensors

This article has 2 authors:
1. Masoud Sepehri Rad
2. Meyer B. Jackson
This article has no evaluationsAppears in 1 listLatest version Oct 4, 2025
Biochemical assessment of α-α-subunit interactions of Na _v 1.5 in a heterologous expression system

This article has 8 authors:
1. Oksana Iamshanova
2. Anne-Flore Hämmerli
3. Suberja Sundaralingam
4. Arbresh Seljmani
5. Sabrina Guichard
6. Maria Essers
7. Jean-Sébastien Rougier
8. Hugues Abriel
This article has no evaluationsAppears in 1 listLatest version Oct 3, 2025
MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants

This article has 5 authors:
1. Aqfan Jamaluddin
2. Rachael A. Wyatt
3. Johannes Broichhagen
4. Joshua Levitz
5. Caroline M. Gorvin
This article has no evaluationsAppears in 1 listLatest version Sep 28, 2025
Mechanism of phosphoinositide regulation of lysosomal pH via inhibition of CLC-7

This article has 10 authors:
1. Jacob K. Hilton
2. Yifei Lin
3. Eric Sefah
4. Justin C. Deme
5. Joanne L. Parker
6. Matthew J. Langton
7. Michael Grabe
8. Susan Lea
9. Simon Newstead
10. Joseph A. Mindell
This article has no evaluationsAppears in 1 listLatest version Oct 2, 2025
Spatial mapping of cell-surface protein glycosylation at molecular resolution

This article has 5 authors:
1. Dijo Moonnukandathil Joseph
2. Nathan Linus Sison
3. Nazlican Yurekli
4. Sheston Culpepper
5. Leonhard Möckl
This article has no evaluationsAppears in 1 listLatest version Oct 1, 2025
Structural insights into a conserved mechanism of choline translocation through CHT

This article has 12 authors:
1. Jesus Vilchez-Garcia
2. Adrián Martínez-Jiménez
3. Hanxing Jiang
4. Borja Ochoa-Lizarralde
5. Jorge Pedro López-Alonso
6. Jerónimo Pérez-Lorente
7. Paola Bartoccioni
8. Raúl Estévez
9. Victor Guallar
10. Ekaitz Errasti-Murugarren
11. Iban Ubarretxena-Belandia
12. Igor Tascón
This article has no evaluationsAppears in 1 listLatest version Oct 1, 2025
Pharmacological inhibition of V-ATPase targets mode-switching but not the proton transport cycle

This article has 10 authors:
1. Eleftherios Kosmidis
2. Maria Fokaeos
3. Christopher G. Shuttle
4. Michael C. Isselstein
5. Aleksander Cvjetkovic
6. Peter J. Johnson
7. Jesper L. Pederesen
8. Reinhard Jahn
9. Julia Preobraschenski
10. Dimitrios Stamou
This article has no evaluationsAppears in 1 listLatest version Sep 30, 2025
Harnessing Protein Unfolding for Thermosensing: Structural Insights from TRPV3

This article has 6 authors:
1. Andrew Njagi Mugo
2. Dinesh Indurthi
3. Ryan Chou
4. Gaya P. Yadav
5. Liguo Wang
6. Feng Qin
This article has no evaluationsAppears in 1 listLatest version Sep 20, 2025
Striatal spinophilin enhances D2R interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression

This article has 4 authors:
1. Basant Hens
2. Whitney R. Smith-Kinneman
3. Emma H. Doud
4. Anthony J. Baucum
This article has no evaluationsAppears in 1 listLatest version Sep 15, 2025
The longer transmembrane helices of class I viral fusion proteins may facilitate viral fusion

This article has 4 authors:
1. Sahil Lall
2. Padmanabhan Balaram
3. M. K. Mathew
4. Shachi Gosavi
This article has no evaluationsAppears in 1 listLatest version Sep 25, 2025
Stabilization versus flexibility: detergent-dependent trade-offs in neurotensin receptor 1 GPCR ensembles

This article has 7 authors:
1. James B. Bower
2. Wijnand J. C. van der Velden
3. Karen P Gomez
4. Mingzhe Pan
5. Fabian Bumbak
6. Nagarajan Vaidehi
7. Joshua J. Ziarek
This article has no evaluationsAppears in 1 listLatest version Sep 24, 2025
Novel Binding Partners of the Vacuolar Transporter Chaperone (VTC) complex in Acidocalcisomes of Leishmania tarentolae

This article has 6 authors:
1. Paulina Królak
2. Orquidea Ribeiro
3. Bernadette Gehl-Väisänen
4. Mimmu K. Hiltunen
5. Adrian Goldman
6. Keni Vidilaseris
This article has no evaluationsAppears in 1 listLatest version Sep 23, 2025
Obstacles Regulate Membrane Tension Propagation to Enable Localized Mechanotransduction

This article has 5 authors:
1. Frederic Català-Castro
2. Mayte Bonilla-Quintana
3. Neus Sanfeliu-Cerdán
4. Padmini Rangamani
5. Michael Krieg
This article has no evaluationsAppears in 1 listLatest version Jan 19, 2025
Cryo-EM of ATP-driven dynamics and itraconazole binding of the fungal drug efflux ABC pump Candida glabrata Cdr1

This article has 22 authors:
1. Jorgaq Pata
2. Benjamin Wiseman
3. Eleftherios Zarkadas
4. Rim Baccouch
5. Nour Samrouth
6. Célia Desbois
7. Loïck Moissonier
8. Alexis Moreno
9. Atanu Banerjee
10. Stéphanie Aguerro
11. Emmanuel Bettler
12. Marie Dujardin
13. Sandrine Magnard
14. Raphaël Terreux
15. Guy Schoehn
16. Martin Högbom
17. Ahcène Boumendjel
18. Erwin Lamping
19. Richard D Cannon
20. Rajendra Prasad
21. Vincent Chaptal
22. Pierre Falson
This article has no evaluationsAppears in 1 listLatest version Sep 22, 2025
Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis

This article has 20 authors:
1. Austin Tedman
2. Muskan Goel
3. Sohan Shah
4. Mathew K. Howard
5. Laura M. Chamness
6. Antonio Bonifasi
7. Ismalia Adams
8. Jacklyn M. Gallagher
9. Wesley D. Penn
10. Katarina Nemec
11. Eli F. McDonald
12. Brianna N. Corman
13. J. Paul Robinson
14. Carol Beth Post
15. Patricia L. Clark
16. M. Madan Babu
17. Aashish Manglik
18. Charles P. Kuntz
19. Willow Coyote-Maestas
20. Jonathan P. Schlebach
This article has no evaluationsAppears in 1 listLatest version Sep 21, 2025
GPR174 Antagonism: Structure, Function, and Dynamics

This article has 2 authors:
1. Vijay Kumar Bhardwaj
2. Alemayehu Gorfe
This article has no evaluationsAppears in 1 listLatest version Sep 19, 2025
Molecular dynamics simulation of the truncated NMDA receptor in the open state

This article has 2 authors:
1. Xing Liu
2. Wenjun Zheng
This article has no evaluationsAppears in 1 listLatest version Sep 18, 2025
Structural basis for color tuning and passive ion conductance in red-shifted pump-fold channelrhodopsin ChR024

This article has 18 authors:
1. Yuka Takeno
2. Seiya Tajima
3. Suhyang Kim
4. Masaki Tsujimura
5. Yuma Ito
6. Masahiro Sugiura
7. Yo Yamashita
8. Koichiro E. Kishi
9. Masahiro Fukuda
10. Seiwa Nakamura
11. Masaya Watanabe
12. Hisako Ikeda
13. Kota Katayama
14. Yuji Furutani
15. Hideki Kandori
16. Hiroshi Ishikita
17. Keiichi Inoue
18. Hideaki E. Kato
This article has no evaluationsAppears in 1 listLatest version Sep 17, 2025
Functional characterization of red-shifted rhodopsin channels from giant viruses explored by a machine-learning model for long-wavelength optogenetics

This article has 17 authors:
1. Shunki Takaramoto
2. Chenxiang Zhao
3. Masayuki Karasuyama
4. Frederik Schulz
5. Masaya Watanabe
6. Yuma Kawasaki
7. Takashi Nagata
8. Masae Konno
9. Naoya Morimoto
10. Masahiro Fukuda
11. Yu Inatsu
12. Hiromu Yawo
13. Oded Béjà
14. Hideaki E. Kato
15. Tanja Woyke
16. Ichiro Takeuchi
17. Keiichi Inoue
This article has no evaluationsAppears in 1 listLatest version Sep 17, 2025

Reading List

Structural mechanism of lipid modulation of pentameric ligand-gated ion channel activity

Plasma membrane-endoplasmic reticulum coupling probed with genetically-encoded voltage sensors

Biochemical assessment of α-α-subunit interactions of Na _v 1.5 in a heterologous expression system

MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants

Mechanism of phosphoinositide regulation of lysosomal pH via inhibition of CLC-7

Spatial mapping of cell-surface protein glycosylation at molecular resolution

Structural insights into a conserved mechanism of choline translocation through CHT

Pharmacological inhibition of V-ATPase targets mode-switching but not the proton transport cycle

Harnessing Protein Unfolding for Thermosensing: Structural Insights from TRPV3

Striatal spinophilin enhances D2R interaction with cytosolic proteins to mediate persistent D2R agonist-induced locomotor suppression

The longer transmembrane helices of class I viral fusion proteins may facilitate viral fusion

Stabilization versus flexibility: detergent-dependent trade-offs in neurotensin receptor 1 GPCR ensembles

Novel Binding Partners of the Vacuolar Transporter Chaperone (VTC) complex in Acidocalcisomes of Leishmania tarentolae

Obstacles Regulate Membrane Tension Propagation to Enable Localized Mechanotransduction

Cryo-EM of ATP-driven dynamics and itraconazole binding of the fungal drug efflux ABC pump Candida glabrata Cdr1

Deep Receptor Scanning Reveals General Sequence Constraints on GPCR Biosynthesis

GPR174 Antagonism: Structure, Function, and Dynamics

Molecular dynamics simulation of the truncated NMDA receptor in the open state

Structural basis for color tuning and passive ion conductance in red-shifted pump-fold channelrhodopsin ChR024

Functional characterization of red-shifted rhodopsin channels from giant viruses explored by a machine-learning model for long-wavelength optogenetics