Reading List

LetA defines a structurally distinct transporter family involved in lipid trafficking

1. Cristina C. Santarossa
2. Yupeng Li
3. Sara Yousef
4. Hale S. Hasdemir
5. Carlos C. Rodriguez
6. Max B. Haase
7. Minkyung Baek
8. Nicolas Coudray
9. John G. Pavek
10. Kimber N. Focke
11. Annika L. Silverberg
12. Carmelita Bautista
13. Johannes Yeh
14. Michael T. Marty
15. David Baker
16. Emad Tajkhorshid
17. Damian C. Ekiert
18. Gira Bhabha

Nanobody-based conjugates targeting small molecule-binding GPCRs and exhibiting logic-gated signaling

1. Shivani Sachdev
2. Swarnali Roy
3. Ross W. Cheloha

GPR27 mediates adrenergic ligands-induced transinhibition of EGFR

1. Sorina Andreea Anghel
2. Rodica Badea
3. Cosmin Trif
4. Teodora Stratulat
5. Cristiana Trita
6. Diana-Georgiana Navligu
7. Stefana M. Petrescu
8. Alexandru Babes
9. Costin-Ioan Popescu
10. Cristin Coman
11. Julien Hanson
12. Sorin Tunaru

The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding

1. Aravind R. Gade
2. Mattia Malvezzi
3. Lala Tanmoy Das
4. Maiko Matsui
5. Cheng-I J. Ma
6. Keon Mazdisnian
7. Steven O. Marx
8. Frederick R. Maxfield
9. Geoffrey S. Pitt

Ion Channel Reaction Networks: Dielectric Screening and the Importance of Off-Pathway Flux

1. Hannah Weckel-Dahman
2. Ryan Carlsen
3. Alexander Daum
4. Maxwell He
5. Tyler G. Southam
6. Jessica M.J. Swanson

Mechanistic Insights into the Substrate Egress Pathways of Human Glucose Transporters GLUT1 and GLUT9

1. Manming Xu
2. Jiwen Jiang
3. Lin Gao
4. Saleh O Alyemni
5. Shozeb Haider

Structural basis of ClC-3 inhibition by TMEM9 and PI(3,5)P ₂

1. Marina Schrecker
2. Yeeun Son
3. Rosa Planells-Cases
4. Sumanta Kar
5. Viktoriia Vorobeva
6. Uwe Schulte
7. Bernd Fakler
8. Thomas J. Jentsch
9. Richard K. Hite

Closed state structure of the pore revealed by uncoupled Shaker K+ channel

1. Yichen Liu
2. Carlos Bassetto
3. Gustavo F. Contreras
4. Eduardo Perozo
5. Francisco Bezanilla

Temporally resolved and interpretable machine learning model of GPCR conformational transition

1. Babgen Manookian
2. Elizaveta Mukhaleva
3. Grigoriy Gogoshin
4. Supriyo Bhattacharya
5. Sivaraj Sivaramakrishnan
6. Nagarajan Vaidehi
7. Andrei S. Rodin
8. Sergio Branciamore

Distinct membrane binding properties of the two non-visual arrestins

1. Thomas D. Killeen
2. Katelyn Tepper
3. Kyle W. Miller
4. Yasmin Aydin
5. Ya Zhuo
6. Shuaitong Zhao
7. Jason M. Conley
8. Rachel Tat
9. Candice S. Klug
10. Adriano Marchese
11. Valerică Raicu
12. Qiuyan Chen

AlphaFold2 captures conformational transitions in the voltage-gated channel superfamily

1. Elaine Tao
2. Ben Corry

Disruption of a side portal pathway permits closed-state inactivation by BK β subunit N termini

1. Yu Zhou
2. Xiao-Ming Xia
3. Christopher J. Lingle

On the mechanism of K+ transport through the inter-subunit tunnel of KdpFABC

1. Hridya Valia Madapally
2. Adel Hussein
3. Martin Wazar Eriksen
4. Bjørn Panyella Pedersen
5. David L. Stokes
6. Himanshu Khandelia

A new corrector rescues F508del-CFTR folding through stabilization of the TMD1-NBD1 linker

1. Peter van der Sluijs
2. Olga Papaioannou
3. Azib Hagos
4. Aya M. Saleh
5. Timothy Hodges
6. Corina Balut
7. Matthew Green
8. Sara Alani
9. Yihong Fan
10. Kazumi Ebine
11. Michael Schrimpf
12. David Hardee
13. Huan-Qiu Li
14. Henry Korman
15. Laura Tade
16. Guus van Zadelhoff
17. Ashvani Singh
18. Chris Tse
19. Ineke Braakman

In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer

1. Edward P. Harvey
2. Jeffrey S. Smith
3. Joseph D. Hurley
4. Alyana J. Granados
5. Ernst W. Schmid
6. Jason G. Liang-Lin
7. Huyang Zhang
8. Emily M. Meara
9. Elizabeth K. Wren
10. Steffanie Paul
11. Matthew P. Ferguson
12. Victor G. Calvillo-Miranda
13. Miguel A. Alcantar
14. Debora S. Marks
15. Johannes C. Walter
16. Andrew C. Kruse
17. Katherine J. Susa

Reviewed by Arcadia Science

Revealing Water-Mediated Activation Mechanisms in the Beta 1-Adrenergic Receptor via OneOPES-Enhanced Free Energy Landscapes

1. Simone Aureli
2. Valerio Rizzi
3. Nicola Piasentin
4. Francesco Luigi Gervasio

Insights into cannabinoid receptor 2 (CB2) anterograde trafficking and pharmacological chaperoning

1. Caitlin R. M. Oyagawa
2. Braden Woodhouse
3. Karren C. Wood
4. Michelle Glass
5. Natasha L. Grimsey

A conserved mechanism of LRRC8 channel inhibition by distinct drugs

1. Toshiki Yamada
2. Paola Bisignano
3. Erkan Karakas
4. Jerod S. Denton

Structure and dynamics of a multidomain ligand-gated ion channel revealed under acidic conditions

1. Olivia Andén
2. Urška Rovšnik
3. Marie Lycksell
4. Marc Delarue
5. Rebecca J Howard
6. Erik Lindahl

Orthosteric interactions with PIP ₂ activate TMEM16A channels

1. J Xu
2. A Santa-Cruz
3. Aishwarya Chandrashekar
4. Takeharu Kawano
5. Mehreen Zaka
6. Meng Cui
7. Diomedes E. Logothetis
8. Leigh D. Plant