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Lipid-mediated mechanism of drug extrusion by a heterodimeric ABC exporter

This article has 6 authors:
1. Qingyu Tang
2. Matt Sinclair
3. Paola Bisignano
4. Yunsen Zhang
5. Emad Tajkhorshid
6. Hassane S. Mchaourab
This article has no evaluationsAppears in 1 listLatest version Feb 28, 2025
Structure of the human TWIK-2 potassium channel and its inhibition by pimozide

This article has 4 authors:
1. Nandish K. Khanra
2. Chongyuan Wang
3. Bryce D. Delgado
4. Stephen B. Long
This article has no evaluationsAppears in 1 listLatest version May 9, 2025
Calcium stabilization of a flexible N-terminal domain in a pentameric ligand-gated ion channel

This article has 5 authors:
1. Chen Fan
2. Marie Lycksell
3. Yuxuan Zhuang
4. Rebecca J. Howard
5. Erik Lindahl
This article has no evaluationsAppears in 1 listLatest version Feb 27, 2025
Structural implications of glycosylation on the voltage-gated sodium channel β3-subunit

This article has 11 authors:
1. Christopher A. Beaudoin
2. Jerrard Hayes
3. Hengrui Liu
4. Sivakumar Namadurai
5. Michael J. Deery
6. Ethan A. August
7. Samuel Krasner
8. Samir W. Hamaia
9. Samantha C. Salvage
10. Christopher L.-H. Huang
11. Antony P. Jackson
This article has no evaluationsAppears in 1 listLatest version Feb 27, 2025
Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation

This article has 12 authors:
1. Su-Yu Ji
2. Wei-Wei Wang
3. Yixin Yang
4. Ping Xu
5. Jiangrong Zhang
6. Xinyue Zhao
7. Kun Xi
8. Shao-Kun Zang
9. Dan-Dan Shen
10. Chunyou Mao
11. Qingya Shen
12. Yan Zhang
This article has no evaluationsAppears in 1 listLatest version Feb 23, 2025
Insights into the structure and modulation of human TWIK-2

This article has 6 authors:
1. Qianqian Ma
2. Ciria C. Hernandez
3. Vikas Navratna
4. Arvind Kumar
5. Abraham Lee
6. Shyamal Mosalaganti
This article has no evaluationsAppears in 1 listLatest version Feb 24, 2025
Optimization of the prostaglandin F _2α receptor for structural biology

This article has 8 authors:
1. Marine Salze
2. Sébastien Chrétien
3. Tegvir S. Boora
4. Madalina Macovei
5. Eric Barbeau
6. Véronique Blais
7. Stéphane A. Laporte
8. Martin Audet
This article has no evaluationsAppears in 1 listLatest version Feb 20, 2025
Molecular mechanism of pH sensing and activation in GPR4 reveals proton-mediated GPCR signaling

This article has 15 authors:
1. Chongzhao You
2. Shimeng Guo
3. Tianwei Zhang
4. Xinheng He
5. Tianyu Gao
6. Wenwen Xin
7. Zining Zhu
8. Yujie Lu
9. Youwei Xu
10. Zhen Li
11. Yumu Zhang
12. Xi Cheng
13. Yi Jiang
14. Xin Xie
15. H. Eric Xu
This article has no evaluationsAppears in 1 listLatest version Jun 25, 2025
Structural basis of vilazodone dual binding mode to the serotonin transporter

This article has 8 authors:
1. Iris E. Kalenderoglou
2. Andreas Nygaard
3. Caleb D. Vogt
4. Anton Turaev
5. Tillmann Pape
6. Nathan B. P. Adams
7. Amy Hauck Newman
8. Claus J. Loland
This article has no evaluationsAppears in 1 listLatest version Nov 18, 2025
Structural basis of ATP release and ion selectivity in Pannexin1 channels

This article has 8 authors:
1. Qingyang Zhang
2. Junjie Wang
3. Guillaume Gaullier
4. David Kotol
5. Cecilia Blikstad
6. Gerhard Dahl
7. Rene Barro-Soria
8. Carsten Mim
This article has no evaluationsAppears in 1 listLatest version Feb 20, 2025
Missense variant analysis in the TRPV1 ARD reveals the unexpected functional significance of a methionine

This article has 6 authors:
1. Grace C. Wulffraat
2. Sanjana Mamathasateesh
3. Rose Hudson
4. Benjamin He
5. Andrés Jara-Oseguera
6. Eric N. Senning
This article has no evaluationsAppears in 1 listLatest version Sep 2, 2025
Cryo-EM reveals a new allosteric binding site at the M ₅ mAChR

This article has 14 authors:
1. Wessel A. C. Burger
2. Jesse I. Mobbs
3. Bhavika Rana
4. Jinan Wang
5. Keya Joshi
6. Patrick R. Gentry
7. Mahmuda Yeasmin
8. Hariprasad Venugopal
9. Aaron M. Bender
10. Craig W. Lindsley
11. Yinglong Miao
12. Arthur Christopoulos
13. Celine Valant
14. David M. Thal
This article has no evaluationsAppears in 1 listLatest version Feb 8, 2025
Key residue Unlocks Dual PIP ₂ -Dependent and Independent Gating in G Protein-Gated Inwardly Rectifying Potassium Channels

This article has 9 authors:
1. Ha Nguyen
2. Jonathan Mount
3. Keino Hutchinson
4. Yihan Zhao
5. Yulin Zhao
6. Ian W Glaaser
7. Peng Yuan
8. Avner Schlessinger
9. Paul A Slesinger
This article has no evaluationsAppears in 1 listLatest version Feb 18, 2025
UB-MBX-46 is a potent and selective antagonist of the human P2X7 receptor developed by structure-based drug design

This article has 14 authors:
1. Adam C. Oken
2. Andreea L. Turcu
3. Eva Tzortzini
4. Kyriakos Georgiou
5. Jessica Nagel
6. Marta Barniol-Xicota
7. Ga-Ram Kim
8. So-Deok Lee
9. Annette Nicke
10. Yong-Chul Kim
11. Christa E. Müller
12. Antonios Kolocouris
13. Santiago Vázquez
14. Steven E. Mansoor
This article has no evaluationsAppears in 1 listLatest version Feb 16, 2025
An integrative model of AMPA receptor trafficking reveals the central contribution of local translation in subtype-specific kinetics

This article has 8 authors:
1. Surbhit Wagle
2. Maximilian K. Kracht
3. Anne Bührke
4. Amparo Acker-Palmer
5. Nataliya Kraynyukova
6. Anne-Sophie Hafner
7. Erin M. Schuman
8. Tatjana Tchumatchenko
This article has no evaluationsAppears in 1 listLatest version Feb 8, 2025
Targeted ubiquitination of Na _V 1.8 reduces sensory neuronal excitability

This article has 10 authors:
1. Sidharth Tyagi
2. Mohammad-Reza Ghovanloo
3. Matthew Alsaloum
4. Philip Effraim
5. Grant P. Higerd-Rusli
6. Fadia Dib-Hajj
7. Peng Zhao
8. Shujun Liu
9. Stephen G. Waxman
10. Sulayman D. Dib-Hajj
This article has no evaluationsAppears in 1 listLatest version Feb 4, 2025
Monoamine-induced diacylglycerol signaling rapidly accumulates Unc13 in nanoclusters for fast presynaptic potentiation

This article has 13 authors:
1. Natalie Blaum
2. Tina Ghelani
3. Torsten Götz
4. Keagan S. Chronister
5. Mercedes Bengochea
6. Christian F. Christensen
7. Thiago C. Moulin
8. Livia Ceresnova
9. Hanna Kern
10. Ulrich Thomas
11. Martin Heine
12. Stephan J. Sigrist
13. Alexander M. Walter
This article has no evaluationsAppears in 1 listLatest version Jan 12, 2025
A two-step clockwork mechanism opens a proteo-lipidic pore in PIEZO2 channels

This article has 7 authors:
1. Shu Li
2. Tharaka Wijerathne
3. Aashish Bhatt
4. Wenjuan Jiang
5. Jerome Lacroix
6. Wei Han
7. Yun Lyna Luo
This article has no evaluationsAppears in 1 listLatest version Feb 14, 2025
Membrane partition and structural reorganization induced by anti-psychotics with distinct clinical profiles

This article has 17 authors:
1. Ana Gorse
2. Vesela Yordanova
3. Jessica Bodosa
4. Marion Mathelié-Guinlet
5. Astrid Walrant
6. Nada Taib-Mamaar
7. Axelle Grélard
8. Claire François-Martin
9. Rim Baccouch
10. Estelle Rascol
11. Gil-mar F. Salgado
12. Maria João Moreno
13. Margarida Bastos
14. Jeffery B. Klauda
15. Galya Staneva
16. Philippe Nuss
17. Isabel D. Alves
This article has no evaluationsAppears in 1 listLatest version Feb 13, 2025
Asymmetric Nature of MscL Opening Revealed by Molecular Dynamics Simulations

This article has 2 authors:
1. Olga N. Rogacheva
2. Wojciech Kopec
This article has no evaluationsAppears in 1 listLatest version Jun 5, 2025