Reading List

Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

1. Parveen Goyal
2. KanagaVijayan Dhanabalan
3. Mariafrancesca Scalise
4. Rosmarie Friemann
5. Cesare Indiveri
6. Renwick CJ Dobson
7. Kutti R Vinothkumar
8. Subramanian Ramaswamy

• Curated by eLife

  eLife Assessment

  This valuable work provides novel insights into the substrate binding mechanism of a tripartite ATP-independent periplasmic (TRAP) transporter, which may be helpful for the development of specific inhibitors. The structural analysis is convincing, but additional work will be required to establish the transport mechanism as well as well as binding sites for all ligands. This study will be of interest to the membrane transport and bacterial biochemistry communities.

Reviewed by eLife

Molecular characterization of Rft1, an ER membrane protein associated with congenital disorder of glycosylation RFT1-CDG

1. Eri Hirata
2. Ken-taro Sakata
3. Grace I. Dearden
4. Faria Noor
5. Indu Menon
6. George N. Chiduza
7. Anant K. Menon

Positive allosteric modulation of a GPCR ternary complex

1. Wessel A. C. Burger
2. Christopher J. Draper-Joyce
3. Celine Valant
4. Arthur Christopoulos
5. David M. Thal

Structural insights into the human P2X1 receptor and ligand interactions

1. Felix M. Bennetts
2. Hariprasad Venugopal
3. Alisa Glukhova
4. Jesse I. Mobbs
5. Sabatino Ventura
6. David M. Thal

Intracellular Pocket Conformations Determine Signaling Efficacy through the μ Opioid Receptor

1. David A. Cooper
2. Joseph DePaolo-Boisvert
3. Stanley A. Nicholson
4. Barien Gad
5. David D. L. Minh

Next-generation neuropeptide Y receptor small-molecule agonists inhibit mosquito-biting behavior

1. Emely V. Zeledon
2. Leigh A. Baxt
3. Tanweer A. Khan
4. Mayako Michino
5. Michael Miller
6. David J. Huggins
7. Caroline S. Jiang
8. Leslie B. Vosshall
9. Laura B. Duvall

Structural basis for CCR6 modulation by allosteric antagonists

1. David Jonathan Wasilko
2. Brian S. Gerstenberger
3. Kathleen A. Farley
4. Wei Li
5. Jennifer Alley
6. Mark E. Schnute
7. Ray J. Unwalla
8. Jorge Victorino
9. Kimberly K. Crouse
10. Ru Ding
11. Parag V. Sahasrabudhe
12. Fabien Vincent
13. Richard K. Frisbie
14. Alpay Dermenci
15. Andrew Flick
16. Chulho Choi
17. Gary Chinigo
18. James J. Mousseau
19. John I. Trujillo
20. Philippe Nuhant
21. Prolay Mondal
22. Vincent Lombardo
23. Daniel Lamb
24. Barbara J. Hogan
25. Gurdeep Singh Minhas
26. Elena Segala
27. Christine Oswald
28. Ian W. Windsor
29. Seungil Han
30. Mathieu Rappas
31. Robert M. Cooke
32. Matthew F. Calabrese
33. Gabriel Berstein
34. Atli Thorarensen
35. Huixian Wu

Reviewed by PREreview

Design, Synthesis and Pharmacological Characterization of the First Photoswitchable Small-Molecule Agonist for the Atypical Chemokine Receptor 3

1. Sophie Bérenger
2. Justyna M. Adamska
3. Francesca Deflorian
4. Chris de Graaf
5. Christie B. Palmer
6. Martyna Szpakowska
7. Andy Chevigné
8. Iwan J. P. de Esch
9. Barbara Zarzycka
10. Henry F. Vischer
11. Maikel Wijtmans
12. Rob Leurs

Core-N-glycans are atypically abundant at the neuronal surface and regulate glutamate receptor signaling

1. Chun-Lei Zhang
2. Cédric Moutoussamy
3. Matthieu Tuffery
4. Alexandre Varangot
5. Rebecca Piskorowski
6. Cyril Hanus

Structure and function of an intermediate GPCR-Gαβγ complex

1. Maxine Bi
2. Xudong Wang
3. Jinan Wang
4. Jun Xu
5. Wenkai Sun
6. Victor Ayo Adediwura
7. Yinglong Miao
8. Yifan Cheng
9. Libin Ye

Toward high-resolution modeling of small molecule–ion channel interactions

1. Brandon J. Harris
2. Phuong T. Nguyen
3. Guangfeng Zhou
4. Heike Wulff
5. Frank DiMaio
6. Vladimir Yarov-Yarovoy

Structure and dynamics determine G protein coupling specificity at a class A GPCR

1. Marina Casiraghi
2. Haoqing Wang
3. Patrick C. Brennan
4. Chris Habrian
5. Harald Hübner
6. Maximilian F. Schmidt
7. Luis Maul
8. Biswaranjan Pani
9. Sherif M. F. M. Bahriz
10. Bing Xu
11. Nico Staffen
12. Tufa E. Assafa
13. Bohan Chen
14. Elizabeth White
15. Roger K. Sunahara
16. Asuka Inoue
17. Yang K. Xiang
18. Robert J. Lefkowitz
19. Ehud Y. Isacoff
20. Nathaniel Nucci
21. Peter Gmeiner
22. Michael T. Lerch
23. Brian K. Kobilka

Cryo-EM insight into hydrogen positions and water networks in photosystem II

1. Rana Hussein
2. André Graça
3. Jack Forsman
4. A. Orkun Aydin
5. Michael Hall
6. Julia Gaetcke
7. Petko Chernev
8. Petra Wendler
9. Holger Dobbek
10. Johannes Messinger
11. Athina Zouni
12. Wolfgang P. Schröder

Essential Dynamics of CB ₁ Receptor-Agonist Complexes: Implications for Signalling Bias

1. Daniel M. J. Fellner
2. Michelle Glass
3. Daniel P. Furkert

High-resolution electron cryomicroscopy of V-ATPase in native synaptic vesicles

1. Claire E. Coupland
2. Ryan Karimi
3. Stephanie A. Bueler
4. Yingke Liang
5. Gautier M. Courbon
6. Justin M. Di Trani
7. Cassandra J. Wong
8. Rayan Saghian
9. Ji-Young Youn
10. Lu-Yang Wang
11. John L. Rubinstein

Kinetic Model for the Desensitization of G Protein-Coupled Receptor

1. Won Kyu Kim
2. Yoonji Lee
3. Seogjoo J. Jang
4. Changbong Hyeon

Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs

1. Jan Hendrik Schmidt
2. Rasmus Herlo
3. Joscha Rombach
4. Andreas Haahr Larsen
5. Mikkel Stoklund
6. Mathias Perslev
7. Tommas Theiss Ehlers Nielsen
8. Keenie Ayla Andersen
9. Carmen Klein Herenbrink
10. Matthew D. Lycas
11. Aske Lykke Ejdrup
12. Nikolaj Riis Christensen
13. Jan P. Christensen
14. Mootaz Salman
15. Freja Herborg
16. Ulrik Gether
17. Alexander Sebastian Hauser
18. Patricia Bassereau
19. David Perrais
20. Kenneth Lindegaard Madsen

Conserved Lysine in transmembrane helix 5 is key for the inner gating of the LAT transporter BasC

1. Joana Fort
2. Adrià Nicolàs-Aragó
3. Luca Maggi
4. Maria Martinez Molledo
5. Despoina Kapiki
6. Niels Zijlstra
7. Susanna Bodoy
8. Els Pardon
9. Jan Steyaert
10. Oscar Llorca
11. Modesto Orozco
12. Thorben Cordes
13. Manuel Palacín

Characterizing the Binding Mechanism of Sparsentan to the Type-2 Angiotensin II Receptor Using AutoDock Vina

1. Peter X. Geng

A metastasis-associated Pannexin1 mutant (Panx1 ^1-89 ) forms a minimalist ATP release channel

1. Junjie Wang
2. Carsten Mim
3. Gerhard Dahll
4. Rene Barro-Soria