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  1. Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure

    This article has 16 authors:
    1. Jun Ishigohoka
    2. Karen BascĂłn-Cardozo
    3. Andrea Bours
    4. Janina FuĂź
    5. Arang Rhie
    6. Jacquelyn Mountcastle
    7. Bettina Haase
    8. William Chow
    9. Joanna Collins
    10. Kerstin Howe
    11. Marcela Uliano-Silva
    12. Olivier Fedrigo
    13. Erich D. Jarvis
    14. Javier PĂ©rez-Tris
    15. Juan Carlos Illera
    16. Miriam Liedvogel

    Reviewed by Peer Community in Evolutionary Biology

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Random genetic drift sets an upper limit on mRNA splicing accuracy in metazoans

    This article has 3 authors:
    1. Florian Bénitière
    2. Anamaria Necsulea
    3. Laurent Duret
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This fundamental study evaluates the evolutionary significance of variations in the accuracy of the intron-splicing process across vertebrates and insects. Using a powerful combination of comparative and population genomics approaches, the authors present convincing evidence that higher rates of alternative splicing tend to be observed in species with lower effective population size, a key prediction of the drift-barrier hypothesis. The analysis is carefully conducted and has broad implications beyond the studied species. As such, it will strongly appeal to anyone interested in the evolution of genome architecture and the optimisation of genetic systems.

    Reviewed by eLife, Peer Community in Evolutionary Biology

    This article has 8 evaluationsAppears in 3 listsLatest version Latest activity