ScreenIT

Latest preprint reviews

1. Changes in ischemic stroke presentations and associated workflow during the first wave of the COVID-19 pandemic: A population study in Alberta, Canada

   This article has 8 authors:

   1. Aravind Ganesh
   2. Jillian M. Stang
   3. Finlay A. McAlister
   4. Oleksandr Shlakhter
   5. Jessalyn K. Holodinsky
   6. Balraj Mann
   7. Michael D. Hill
   8. Eric E. Smith

   Reviewed by ScreenIT

2. Detection and quantification of SARS-CoV-2 RNA in wastewater influent in relation to reported COVID-19 incidence in Finland

   This article has 12 authors:

   1. Ananda Tiwari
   2. Anssi Lipponen
   3. Anna-Maria Hokajärvi
   4. Oskari Luomala
   5. Anniina Sarekoski
   6. Annastiina Rytkönen
   7. Pamela Österlund
   8. Haider Al-Hello
   9. Aapo Juutinen
   10. Ilkka T. Miettinen
   11. Carita Savolainen-Kopra
   12. Tarja Pitkänen

   Reviewed by ScreenIT

3. Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients

   This article has 35 authors:

   1. Jessica Bassi
   2. Olivier Giannini
   3. Chiara Silacci-Fregni
   4. Laura Pertusini
   5. Paolo Hitz
   6. Tatiana Terrot
   7. Yves Franzosi
   8. Francesco Muoio
   9. Christian Saliba
   10. Marcel Meury
   11. Exequiel A. Dellota
   12. Josh R. Dillen
   13. Patrick Hernandez
   14. Nadine Czudnochowski
   15. Elisabetta Cameroni
   16. Nicola Beria
   17. Mariangela Ventresca
   18. Alberto Badellino
   19. Soraya Lavorato-Hadjeres
   20. Elisabetta Lecchi
   21. Tecla Bonora
   22. Matteo Mattiolo
   23. Guido Trinci
   24. Daniela Garzoni
   25. Giuseppe Bonforte
   26. Valentina Forni-Ogna
   27. Davide Giunzioni
   28. Lorenzo Berwert
   29. Ravindra K. Gupta
   30. Paolo Ferrari
   31. Alessandro Ceschi
   32. Pietro Cippà
   33. Davide Corti
   34. Antonio Lanzavecchia
   35. Luca Piccoli

   Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

4. Covid-19 vaccine perceptions in Senegal and in Mali: a mixed approach

   This article has 8 authors:

   1. Eleonore Fournier-Tombs
   2. Massamba Diouf
   3. Abdine Maiga
   4. Sylvain Faye
   5. Tidiane Ndoye
   6. Lalla Haidara
   7. Moussa Batchily
   8. Céline Castet-Renard

   Reviewed by ScreenIT

5. Adverse Events Following COVID-19 Vaccination in Young Japanese People: A Case-Control Study of the Risk of Systemic Adverse Events by A Questionnaire Survey

   This article has 10 authors:

   1. Marie Suehiro
   2. Shinya Okubo
   3. Kensuke Nakajima
   4. Kosuke Kanda
   5. Masanobu Hayakawa
   6. Shigeru Oiso
   7. Tsutomu Kabashima
   8. Hideaki Fujita
   9. Yukio Ando
   10. Takahiro Muro

   Reviewed by ScreenIT

6. SARS-CoV-2 RNA and antibody dynamics in a Dutch household study with dense sampling frame

   This article has 26 authors:

   1. Wanda G. H. Han
   2. Arno Swart
   3. Axel Bonačić Marinović.
   4. Dirk Eggink
   5. Johan Reimerink
   6. Lisa A. Wijsman
   7. Bas van der Veer
   8. Sharon van den Brink
   9. Anne-Marie van den Brandt
   10. Sophie van Tol
   11. Gert-Jan Godeke
   12. Fion Brouwer
   13. Marieke Hoogerwerf
   14. The Dutch F. F. X.-COVID-19 Research Group
   15. Arianne B. van Gageldonk-Lafeber
   16. Wim van der Hoek
   17. Susan van den Hof
   18. Adam Meijer
   19. Daphne F. M. Reukers
   20. Chantal Reusken
   21. Inge Roof
   22. Nynke Rots
   23. Daphne F. M. Reukers
   24. Nynke Rots
   25. Chantal Reusken
   26. Adam Meijer

   Reviewed by ScreenIT

7. Seropositivity to Nucleoprotein to detect mild and asymptomatic SARS-CoV-2 infections: A complementary tool to detect breakthrough infections after COVID-19 vaccination?

   This article has 21 authors:

   1. Lotus L. van den Hoogen
   2. Gaby Smits
   3. Cheyenne C.E. van Hagen
   4. Denise Wong
   5. Eric R.A. Vos
   6. Michiel van Boven
   7. Hester E. de Melker
   8. Jeffrey van Vliet
   9. Marjan Kuijer
   10. Linde Woudstra
   11. Alienke J. Wijmenga-Monsuur
   12. Corine H. GeurtsvanKessel
   13. Susanne P. Stoof
   14. Daphne Reukers
   15. Lisa A. Wijsman
   16. Adam Meijer
   17. Chantal B.E.M. Reusken
   18. Nynke Y. Rots
   19. Fiona R.M. van der Klis
   20. Robert S. van Binnendijk
   21. Gerco den Hartog

   Reviewed by ScreenIT

8. Evolution of SARS-CoV-2 immune responses in nursing home residents following full dose of the Comirnaty® COVID-19 vaccine

   This article has 13 authors:

   1. Estela Giménez
   2. Juan Alberola
   3. Ignacio Torres
   4. Eliseo Albert
   5. María Jesús Alcaraz
   6. Pilar Botija
   7. Paula Amat
   8. María José Remigia
   9. María José Beltrán
   10. Celia Rodado
   11. Dixie Huntley
   12. Beatriz Olea
   13. David Navarro

   Reviewed by ScreenIT

9. Efficacy and Safety of MSC Cell Therapies for Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis

   This article has 22 authors:

   1. Wenchun Qu
   2. Zhen Wang
   3. Erica Engelberg-Cook
   4. Dan Yan
   5. Abu Bakar Siddik
   6. Guojun Bu
   7. Julie G Allickson
   8. Eva Kubrova
   9. Arnold I Caplan
   10. Joshua M Hare
   11. Camillo Ricordi
   12. Carl J Pepine
   13. Joanne Kurtzberg
   14. Jorge M Pascual
   15. Jorge M Mallea
   16. Ricardo L Rodriguez
   17. Tarek Nayfeh
   18. Samer Saadi
   19. Ravindra V Durvasula
   20. Elaine M Richards
   21. Keith March
   22. Fred P Sanfilippo

   Reviewed by ScreenIT

10. Comprehensive characterization of the antibody responses to SARS-CoV-2 Spike protein finds additional vaccine-induced epitopes beyond those for mild infection

    This article has 8 authors:

    1. Meghan E Garrett
    2. Jared G Galloway
    3. Caitlin Wolf
    4. Jennifer K Logue
    5. Nicholas Franko
    6. Helen Y Chu
    7. Frederick A Matsen
    8. Julie M Overbaugh

    This article has been curated by 1 group:

    • Curated by eLife

      Evaluation Summary:

      The authors used phage display deep mutational scanning of SARS-CoV-2 Spike protein to profile antibody epitopes outside of the RBD that were recognized in two cohorts of subjects, which together included mRNA vaccinated, SARS-CoV-2 infected with mild or severe COVID-19 and vaccinated with prior infection. Key findings of the study are that severe COVID-19 and vaccinated individuals had higher binding to Spike protein regions NTD, CTD, and SH-H compared to individuals with mild COVID-19, while mild COVID-19 infections had higher binding to FP than vaccinated or severe COVID-19 individuals. They also reported that vaccinated individuals with or without prior infection were not different and that covariates did not appear to impact the antibody recognition profiles. The authors identified potential escape pathways in these epitope regions, some of which differed between vaccination and infection or drifted over time. The authors acknowledge that this approach is limited to linear epitopes and does not include RBD epitopes. However, the study provides novel insight into the major epitope regions targeted by polyclonal antibodies elicited by vaccination vs. infection, as well as potential pathways for the virus to escape recognition.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife, ScreenIT