ScreenIT

Latest preprint reviews

1. T-cell Repertoire Characteristics of Asymptomatic and Re-detectable Positive COVID-19 Patients

   This article has 16 authors:

   1. Jianhua Xu
   2. Yaling Shi
   3. Yongsi Wang
   4. Yuntao Liu
   5. Dongzi Lin
   6. Jiaqi Zhang
   7. Jing Lin
   8. Wei Hu
   9. Haolan He
   10. Wei Wang
   11. Wentao Fan
   12. Linlin Li
   13. Hai Lan
   14. Chunliang Lei
   15. Kejian Wang
   16. Dawei Wang

   Reviewed by ScreenIT

2. Recombinant chimpanzee adenovirus AdC7 expressing dimeric tandem-repeat RBD of SARS-CoV-2 spike protein protects mice against COVID-19

   This article has 20 authors:

   1. Kun Xu
   2. Yaling An
   3. Qunlong Li
   4. Weijin Huang
   5. Yuxuan Han
   6. Tianyi Zheng
   7. Fang Fang
   8. Hui Liu
   9. Chuanyu Liu
   10. Ping Gao
   11. Senyu Xu
   12. William J. Liu
   13. Yuhai Bi
   14. Youchun Wang
   15. Dongming Zhou
   16. Qinghan Wang
   17. Wenli Hou
   18. Qianfeng Xia
   19. George F. Gao
   20. Lianpan Dai

   Reviewed by ScreenIT

3. Detection of SARS-CoV-2 infection by saliva and nasopharyngeal sampling in frontline healthcare workers: An observational cohort study

   This article has 28 authors:

   1. Naomi F. Walker
   2. Rachel L. Byrne
   3. Ashleigh Howard
   4. Elissavet Nikolaou
   5. Madlen Farrar
   6. Sharon Glynn
   7. Katerina S. Cheliotis
   8. Ana I. Cubas Atienzar
   9. Kelly Davies
   10. Jesús Reiné
   11. Zalina Rashid-Gardner
   12. Esther L. German
   13. Carla Solórzano
   14. Tess Blandamer
   15. Lisa Hitchins
   16. Christopher Myerscough
   17. Bradford D. Gessner
   18. Elizabeth Begier
   19. Andrea M. Collins
   20. Mike Beadsworth
   21. Stacy Todd
   22. Helen Hill
   23. Catherine F. Houlihan
   24. Eleni Nastouli
   25. Emily R. Adams
   26. Elena Mitsi
   27. Daniela M. Ferreira
   28. on behalf of the SAFER investigators

   Reviewed by ScreenIT

4. The Relationship between COVID-19 Severity and Bacillus Calmette-Guérin (BCG)/ Mycobacterium tuberculosis exposure history in healthcare workers: a multi-center study

   This article has 34 authors:

   1. Serife Torun
   2. Sevket Ozkaya
   3. Nazan Şen
   4. Fikret Kanat
   5. Irem Karaman
   6. Sebnem Yosunkaya
   7. Ozlem Sengoren Dikis
   8. Ali Asan
   9. Selma Aydogan Eroglu
   10. Sefa Semih Atal
   11. Omer Ayten
   12. Nimet Aksel
   13. Hilal Ermiş
   14. Neslihan Özçelik
   15. Meryem Demirelli
   16. Iskender Kara
   17. Sua Sümer
   18. Kamile Marakoğlu
   19. Fatih Üzer
   20. Yasin Uyar
   21. Tuba Çiçek
   22. Zuhal E Ünsal
   23. Husamettin Vatansev
   24. Berna Botan Yildirim
   25. Tuba Kuruoğlu
   26. Aynur Atilla
   27. Yasemin Ersoy
   28. Bahar Kandemir
   29. Yasemin Durduran
   30. Fatma Goksin​ Cihan
   31. Nur Demirbaş
   32. Fatma Yıldırım
   33. Dursun Tatar
   34. M Sule Akcay

   Reviewed by ScreenIT

5. Potential global impact of the N501Y mutation on MHC-II presentation and immune escape

   This article has 3 authors:

   1. Andrea Castro
   2. Hannah Carter
   3. Maurizio Zanetti

   Reviewed by ScreenIT

6. Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy

   This article has 8 authors:

   1. Sierra M Barone
   2. Alberta GA Paul
   3. Lyndsey M Muehling
   4. Joanne A Lannigan
   5. William W Kwok
   6. Ronald B Turner
   7. Judith A Woodfolk
   8. Jonathan M Irish

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     The three reviewers were overly positive about the stated goal of your T-REX method to characterize rare populations by cytometry. The potential applications in the context of analyzing antigen-specific T cells (as identified as tetramer-positive cells) were not missed on the reviewers and the use of the 2 timepoints-cohort of samples from rhinovirus-infected patients was judged clever. However, all three reviewers requested some edits and additional tests to really distinguish T-REX from other methods in terms of performance, and to better understand its analysis power. Reviewer #1 enjoined you to clarify the improvements of your method compared to previous methods. Reviewer #2 requested more stringent tests of your methods against functional datasets. Reviewer #3 inquired about corrections for batch effects, the result consistency for repeated down-sampling as well as the scalability of the method (especially when UMAP is being used).

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 and Reviewer #3 agreed to share their names with the authors.)

   Reviewed by eLife, ScreenIT

7. LRR protein RNH1 dampens the inflammasome activation and is associated with adverse clinical outcomes in COVID-19 patients

   This article has 20 authors:

   1. Giuseppe Bombaci
   2. Mayuresh Anant Sarangdhar
   3. Nicola Andina
   4. Aubry Tardivel
   5. Eric Chi-Wang Yu
   6. Gillian M. Mackie
   7. Matthew Pugh
   8. Vedat Burak Ozan
   9. Yara Banz
   10. Thibaud Spinetti
   11. Cedric Hirzel
   12. Esther Youd
   13. Joerg C. Schefold
   14. Graham Taylor
   15. Amiq Gazdhar
   16. Nicolas Bonadies
   17. Anne Angelillo-Scherrer
   18. Pascal Schneider
   19. Kendle M. Maslowski
   20. Ramanjaneyulu Allam

   Reviewed by ScreenIT

8. COVID-19 Pandemic and Exercise (COPE) trial: a multigroup pragmatic randomised controlled trial examining effects of app-based at-home exercise programs on depressive symptoms

   This article has 9 authors:

   1. Eli Puterman
   2. Benjamin Hives
   3. Nicole Mazara
   4. Nikol Grishin
   5. Joshua Webster
   6. Stacey Hutton
   7. Michael Stephen Koehle
   8. Yan Liu
   9. Mark R Beauchamp

   Reviewed by ScreenIT

9. REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters

   This article has 36 authors:

   1. Alina Baum
   2. Dharani Ajithdoss
   3. Richard Copin
   4. Anbo Zhou
   5. Kathryn Lanza
   6. Nicole Negron
   7. Min Ni
   8. Yi Wei
   9. Kusha Mohammadi
   10. Bret Musser
   11. Gurinder S. Atwal
   12. Adelekan Oyejide
   13. Yenny Goez-Gazi
   14. John Dutton
   15. Elizabeth Clemmons
   16. Hilary M. Staples
   17. Carmen Bartley
   18. Benjamin Klaffke
   19. Kendra Alfson
   20. Michal Gazi
   21. Olga Gonzalez
   22. Edward Dick
   23. Ricardo Carrion
   24. Laurent Pessaint
   25. Maciel Porto
   26. Anthony Cook
   27. Renita Brown
   28. Vaneesha Ali
   29. Jack Greenhouse
   30. Tammy Taylor
   31. Hanne Andersen
   32. Mark G. Lewis
   33. Neil Stahl
   34. Andrew J. Murphy
   35. George D. Yancopoulos
   36. Christos A. Kyratsous

   Reviewed by ScreenIT

10. Regional opening strategies with commuter testing and containment of new SARS-CoV-2 variants in Germany

    This article has 12 authors:

    1. Martin J. Kühn
    2. Daniel Abele
    3. Sebastian Binder
    4. Kathrin Rack
    5. Margrit Klitz
    6. Jan Kleinert
    7. Jonas Gilg
    8. Luca Spataro
    9. Wadim Koslow
    10. Martin Siggel
    11. Michael Meyer-Hermann
    12. Achim Basermann

    Reviewed by ScreenIT