ScreenIT

Latest preprint reviews

1. Enisamium Inhibits SARS-CoV-2 RNA Synthesis

   This article has 15 authors:

   1. Stefano Elli
   2. Denisa Bojkova
   3. Marco Bechtel
   4. Thomas Vial
   5. David Boltz
   6. Miguel Muzzio
   7. Xinjian Peng
   8. Federico Sala
   9. Cesare Cosentino
   10. Andrew Goy
   11. Marco Guerrini
   12. Lutz Müller
   13. Jindrich Cinatl
   14. Victor Margitich
   15. Aartjan J. W. te Velthuis

   Reviewed by ScreenIT

2. COVID-19: Short term prediction model using daily incidence data

   This article has 8 authors:

   1. Hongwei Zhao
   2. Naveed N. Merchant
   3. Alyssa McNulty
   4. Tiffany A. Radcliff
   5. Murray J. Cote
   6. Rebecca S. B. Fischer
   7. Huiyan Sang
   8. Marcia G. Ory

   Reviewed by ScreenIT

3. Risk of Corona virus disease 2019 (COVID-19) among spectacles wearing population of Northern India

   This article has 1 author:

   1. Amit Kumar Saxena

   Reviewed by ScreenIT

4. A cell phone data driven time use analysis of the COVID-19 epidemic

   This article has 4 authors:

   1. Eli P. Fenichel
   2. Kevin Berry
   3. Jude Bayham
   4. Gregg Gonsalves

   Reviewed by ScreenIT

5. The common interests of health protection and the economy: evidence from scenario calculations of COVID-19 containment policies

   This article has 12 authors:

   1. Florian Dorn
   2. Sahamoddin Khailaie
   3. Marc Stoeckli
   4. Sebastian C. Binder
   5. Tanmay Mitra
   6. Berit Lange
   7. Stefan Lautenbacher
   8. Andreas Peichl
   9. Patrizio Vanella
   10. Timo Wollmershäuser
   11. Clemens Fuest
   12. Michael Meyer-Hermann

   Reviewed by ScreenIT

6. Hydroxyzine inhibits SARS-CoV-2 Spike protein binding to ACE2 in a qualitative in vitro assay

   This article has 3 authors:

   1. Maria Dolores Rivas
   2. Jose Maria Rafael Saponi-Cortes
   3. Jose Zamorano

   Reviewed by ScreenIT

7. Act early, save lives: managing COVID-19 in Greece

   This article has 3 authors:

   1. Ilias Gountas
   2. Georgios Hillas
   3. Kyriakos Souliotis

   Reviewed by ScreenIT

8. Early impact of school closure and social distancing for COVID-19 on the number of inpatients with childhood non-COVID-19 acute infections in Japan

   This article has 7 authors:

   1. Kenji Kishimoto
   2. Seiko Bun
   3. Jung-ho Shin
   4. Daisuke Takada
   5. Tetsuji Morishita
   6. Susumu Kunisawa
   7. Yuichi Imanaka

   Reviewed by ScreenIT

9. Cardiometabolic risks of SARS-CoV-2 hospitalization using Mendelian Randomization

   This article has 2 authors:

   1. Noah Lorincz-Comi
   2. Xiaofeng Zhu

   Reviewed by ScreenIT

10. Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19

    This article has 21 authors:

    1. Courtney Tindle
    2. MacKenzie Fuller
    3. Ayden Fonseca
    4. Sahar Taheri
    5. Stella-Rita Ibeawuchi
    6. Nathan Beutler
    7. Gajanan Dattatray Katkar
    8. Amanraj Claire
    9. Vanessa Castillo
    10. Moises Hernandez
    11. Hana Russo
    12. Jason Duran
    13. Laura E Crotty Alexander
    14. Ann Tipps
    15. Grace Lin
    16. Patricia A Thistlethwaite
    17. Ranajoy Chattopadhyay
    18. Thomas F Rogers
    19. Debashis Sahoo
    20. Pradipta Ghosh
    21. Soumita Das

    This article has been curated by 1 group:

    • Curated by eLife

      Evaluation Summary:

      The manuscript by Tindle et al describes generation of adult lung organoids (ALO) from human lung biopsies and their use to study the changes in gene expression as a result of SARS-CoV-2 infection. In this particular case the authors report the presence of AT1, AT2 cells, Basal cells, Goblet cells, Ciliated cells and Club cells. The authors were able to cultivate the cells at the air-liquid interface and to establish cultures of predominately proximal and predominately distal airway cells. The main finding is that proximal cells are more prone to viral infection, while distal cells are governing the exuberant inflammatory response, with both cells required for the exuberant response to occur. Useful information provided by the paper is the analysis gene signatures of various cellular models, in comparison to the infected human lung.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their names with the authors.)

    Reviewed by eLife, ScreenIT