ScreenIT

Latest preprint reviews

1. A Standard-Based Citywide Health Information Exchange for Public Health in Response to COVID-19: Development Study

   This article has 8 authors:

   1. Bala Hota
   2. Paul Casey
   3. Anne F McIntyre
   4. Jawad Khan
   5. Shafiq Rab
   6. Aneesh Chopra
   7. Omar Lateef
   8. Jennifer E Layden

   Reviewed by ScreenIT

2. Safety-Critical Control of Active Interventions for COVID-19 Mitigation

   This article has 4 authors:

   1. Aaron D. Ames
   2. Tamás G. Molnár
   3. Andrew W. Singletary
   4. Gábor Orosz

   Reviewed by ScreenIT

3. Modelling the potential spread of virus during soccer matches

   This article has 3 authors:

   1. Nikolas Sten Knudsen
   2. Manuel Mounir Demetry Thomasen
   3. Thomas Bull Andersen

   Reviewed by ScreenIT

4. Diagnosis of COVID-19 from X-rays Using Combined CNN-RNN Architecture with Transfer Learning

   This article has 6 authors:

   1. Mabrook S. Al-Rakhami
   2. Md. Milon Islam
   3. Md. Zabirul Islam
   4. Amanullah Asraf
   5. Ali Hassan Sodhro
   6. Weiping Ding

   Reviewed by ScreenIT

5. Inheritance of a common androgen synthesis variant allele is associated with female COVID susceptibility in UK Biobank

   This article has 4 authors:

   1. Jeffrey M McManus
   2. Navin Sabharwal
   3. Peter Bazeley
   4. Nima Sharifi

   Reviewed by ScreenIT

6. Transmission of SARS-CoV-2 before and after symptom onset: impact of nonpharmaceutical interventions in China

   This article has 5 authors:

   1. Mary Bushman
   2. Colin Worby
   3. Hsiao-Han Chang
   4. Moritz U. G. Kraemer
   5. William P. Hanage

   Reviewed by ScreenIT

7. Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective

   This article has 20 authors:

   1. Mona Seifert
   2. Subhas Chandra Bera
   3. Pauline van Nies
   4. Robert N. Kirchdoerfer
   5. Ashleigh Shannon
   6. Thi-Tuyet-Nhung Le
   7. Xiangzhi Meng
   8. Hongjie Xia
   9. James M. Wood
   10. Lawrence D. Harris
   11. Flávia S. Papini
   12. Jamie J. Arnold
   13. Steven C. Almo
   14. Tyler L. Grove
   15. Pei-Yong Shi
   16. Yan Xiang
   17. Bruno Canard
   18. Martin Depken
   19. Craig E. Cameron
   20. David Dulin

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     This work presented in this manuscript paper may advance our understanding of an important class of anti-viral drugs (nucleoside analogs) that target polymerase enzymes by being directly incorporated into the product strand. This class of drugs is known to be quite diverse in their precise mechanisms of action, yet many of the particular details have remained elusive, often due to experimental limitations. The current study employs a single-molecule magnetic-tweezers platform to provide a new paradigm for the mechanism of drug remdesivir against the SARS-CoV-2 polymerase target. The authors propose that remdesivir does not prevent the complete viral RNA synthesis but causes an increase of polymerase pausing and back tracking. This paper is of broad interest to readers and scientists working on SARS-CoV-2 and general nucleotide inhibitors. The work includes the single molecule characterization of other NAs.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

   Reviewed by eLife, ScreenIT

8. Estimating the Cumulative Incidence of SARS-CoV-2 Infection and the Infection Fatality Ratio in Light of Waning Antibodies

   This article has 9 authors:

   1. Kayoko Shioda
   2. Max S.Y. Lau
   3. Alicia N.M. Kraay
   4. Kristin N. Nelson
   5. Aaron J. Siegler
   6. Patrick S. Sullivan
   7. Matthew H. Collins
   8. Joshua S. Weitz
   9. Benjamin A. Lopman

   Reviewed by ScreenIT

9. High infectiousness immediately before COVID-19 symptom onset highlights the importance of continued contact tracing

   This article has 3 authors:

   1. William S Hart
   2. Philip K Maini
   3. Robin N Thompson

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     The manuscript uses a new approach to model the infectiousness profile of COVID-19 infected individuals. The work suggests a higher proportion of pre-symptomatic infectiousness in COVID-19 than the current evidence. The findings are of great interest to public health policy makers. The methodology is of general interest to modellers working on COVID-19.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 and Reviewer #3 agreed to share their names with the authors.)

   Reviewed by eLife, ScreenIT

10. The Potential Role of an Aberrant Mucosal Immune Response to SARS-CoV-2 in the Pathogenesis of IgA Nephropathy

    This article has 9 authors:

    1. Zhao Zhang
    2. Guorong Zhang
    3. Meng Guo
    4. Wanyin Tao
    5. Xingzi Liu
    6. Haiming Wei
    7. Tengchuan Jin
    8. Yuemiao Zhang
    9. Shu Zhu

    Reviewed by ScreenIT