preLights

Latest preprint reviews

1. Parallel gene size and isoform expansion of ancient neuronal genes

   This article has 2 authors:

   1. Matthew J. McCoy
   2. Andrew Z. Fire

   Reviewed by preLights

2. Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation

   This article has 4 authors:

   1. Courtney M. Clark-Hachtel
   2. Jonathan D. Hibshman
   3. Tristan De Buysscher
   4. Bob Goldstein

   Reviewed by preLights

3. NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections

   This article has 23 authors:

   1. Björn Klabunde
   2. André Wesener
   3. Wilhelm Bertrams
   4. Isabell Beinborn
   5. Nicole Paczia
   6. Kristin Surmann
   7. Sascha Blankenburg
   8. Jochen Wilhelm
   9. Javier Serrania
   10. Kèvin Knoops
   11. Eslam M. Elsayed
   12. Katrin Laakmann
   13. Anna Lena Jung
   14. Andreas Kirschbaum
   15. Sven Hammerschmidt
   16. Belal Alshaar
   17. Nicolas Gisch
   18. Mobarak Abu Mraheil
   19. Anke Becker
   20. Uwe Völker
   21. Evelyn Vollmeister
   22. Birke J. Benedikter
   23. Bernd Schmeck

   Reviewed by preLights

4. NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

   This article has 11 authors:

   1. Hayden T. Pacl
   2. Krishna C. Chinta
   3. Vineel P. Reddy
   4. Sajid Nadeem
   5. Ritesh R. Sevalkar
   6. Kierveshan Nargan
   7. Kapongo Lumamba
   8. Threnesan Naidoo
   9. Joel N. Glasgow
   10. Anupam Agarwal
   11. Adrie J. C. Steyn

   Reviewed by preLights

5. Mentoring practices predictive of doctoral student outcomes in a biological sciences cohort

   This article has 3 authors:

   1. Reena Debray
   2. Emily A. Dewald-Wang
   3. Katherine K. Ennis

   Reviewed by preLights

6. PUFFFIN: A novel, ultra-bright, customisable, single-plasmid system for labelling cell neighbourhoods

   This article has 4 authors:

   1. Tamina Lebek
   2. Mattias Malaguti
   3. Alistair Elfick
   4. Sally Lowell

   Reviewed by Review Commons, preLights

7. Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

   This article has 10 authors:

   1. Mrityunjoy Kar
   2. Laura T. Vogel
   3. Gaurav Chauhan
   4. Hannes Ausserwöger
   5. Timothy J. Welsh
   6. Anjana R. Kamath
   7. Tuomas P. J. Knowles
   8. Anthony A. Hyman
   9. Claus A. M. Seidel
   10. Rohit V. Pappu

   Reviewed by preLights

8. The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals

   This article has 29 authors:

   1. Christine E. Schnitzler
   2. E. Sally Chang
   3. Justin Waletich
   4. Gonzalo Quiroga-Artigas
   5. Wai Yee Wong
   6. Anh-Dao Nguyen
   7. Sofia N. Barreira
   8. Liam B. Doonan
   9. Paul Gonzalez
   10. Sergey Koren
   11. James M. Gahan
   12. Steven M. Sanders
   13. Brian Bradshaw
   14. Timothy Q. DuBuc
   15. Febrimarsa
   16. Danielle de Jong
   17. Eric P. Nawrocki
   18. Alexandra Larson
   19. Samantha Klasfeld
   20. Sebastian G. Gornik
   21. R. Travis Moreland
   22. Tyra G. Wolfsberg
   23. Adam M. Phillippy
   24. James C. Mullikin
   25. Oleg Simakov
   26. Paulyn Cartwright
   27. Matthew Nicotra
   28. Uri Frank
   29. Andreas D. Baxevanis

   Reviewed by preLights

9. TLR2 regulates hair follicle cycle and regeneration via BMP signaling

   This article has 10 authors:

   1. Luyang Xiong
   2. Irina Zhevlakova
   3. Xiaoxia Z West
   4. Detao Gao
   5. Rakhilya Murtazina
   6. Anthony Horak
   7. J Mark Brown
   8. Iuliia Molokotina
   9. Eugene A Podrez
   10. Tatiana V Byzova

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     Toll like receptor 2 (TLR2) signaling has traditionally been viewed a surface protein that induces innate immune responses and improves acquired immunity. Here, the authors suggest a different role for TLR2 in the hair cycle. By using a Cre reporter that is largely, but not solely active in hair follicle stem cells, the authors conditionally delete Tlr2 in mice and report that BMP signaling is sustained and hair cycle entry is delayed. Delving further, the authors identify CEP (2-ω-carboxyethyl pyrrole) as an endogenous ligand of TLR2 in hair follicle stem cell regulation. Although a role for TLR2 signaling in hair follicle stem cells is potentially novel and important, the reviewers remain in consensus that evidence presented in two significant areas continues to be incomplete: 1) where TLR2 and CEP are expressed and how specific is their expression to the hair follicle stem cells; 2) whether as the authors suggest, TLR2 functions by regulating BMP signaling in the stem cell niche of the hair follicle.

   Reviewed by eLife, preLights

10. Optical Control of G-Actin with a Photoswitchable Latrunculin

    This article has 13 authors:

    1. Nynke A. Vepřek
    2. Madeline H. Cooper
    3. Laura Laprell
    4. Emily Jie-Ning Yang
    5. Sander Folkerts
    6. Ruiyang Bao
    7. Malgorzata Boczkowska
    8. Nicholas J. Palmer
    9. Roberto Dominguez
    10. Thomas G. Oertner
    11. Liza A. Pon
    12. J. Bradley Zuchero
    13. Dirk H. Trauner

    Reviewed by preLights