preLights

Latest preprint reviews

1. HIF1A-mediated pathways promote euploid cell survival in chromosomally mosaic embryos

   This article has 3 authors:

   1. Estefania Sanchez-Vasquez
   2. Marianne E Bronner
   3. Magdalena Zernicka-Goetz

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     Sanchez-Vasquez et al establish an innovative approach to induce aneuploidy in preimplantation embryos. This important study extends the author's previous publications evaluating the consequences of aneuploidy in the mammalian embryo. In this work, the authors investigate the developmental potential of aneuploid embryos and characterize changes in gene expression profiles under normoxic and hypoxic culture conditions. Using a solid methodology they identify sensitivity to Hif1alpha loss in aneuploid embryos, and in further convincing experiments they assess how levels of DNA damage and DNA repair are altered under hypoxic and normoxic conditions.

   Reviewed by eLife, preLights

2. Global coordination of protrusive forces in migrating immune cells

   This article has 11 authors:

   1. Patricia Reis-Rodrigues
   2. Nikola Canigova
   3. Mario J. Avellaneda
   4. Florian Gaertner
   5. Kari Vaahtomeri
   6. Michael Riedl
   7. Jack Merrin
   8. Robert Hauschild
   9. Yoshinori Fukui
   10. Alba Juanes Garcia
   11. Michael Sixt

   Reviewed by preLights

3. Axis reset is rate limiting for onset of whole-body regenerative abilities during planarian development

   This article has 5 authors:

   1. Clare L.T. Booth
   2. Brian C. Stevens
   3. Clover A. Stubbert
   4. Neil T. Kallgren
   5. Erin L. Davies

   Reviewed by preLights

4. Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity

   This article has 9 authors:

   1. Keisuke Motone
   2. Daphne Kontogiorgos-Heintz
   3. Jasmine Wee
   4. Kyoko Kurihara
   5. Sangbeom Yang
   6. Gwendolin Roote
   7. Yishu Fang
   8. Nicolas Cardozo
   9. Jeff Nivala

   Reviewed by preLights

5. Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

   This article has 16 authors:

   1. John M. Bennett
   2. Sunil K. Narwal
   3. Stephanie Kabeche
   4. Daniel Abegg
   5. Vandana Thathy
   6. Fiona Hackett
   7. Tomas Yeo
   8. Veronica L. Li
   9. Ryan Muir
   10. Franco Faucher
   11. Scott Lovell
   12. Michael J. Blackman
   13. Alexander Adibekian
   14. Ellen Yeh
   15. David A. Fidock
   16. Matthew Bogyo

   Reviewed by preLights

6. Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

   This article has 19 authors:

   1. Frédéric Fercoq
   2. Gemma S. Cairns
   3. Marco De Donatis
   4. John B. G. Mackey
   5. Alessia Floerchinger
   6. Amanda McFarlane
   7. Ximena L. Raffo-Iraolagoitia
   8. Declan Whyte
   9. Lindsey W. G. Arnott
   10. Colin Nixon
   11. Robert Wiesheu
   12. Anna Kilbey
   13. Leah Brown
   14. Sarwah Al-Khalidi
   15. Jim C. Norman
   16. Edward W. Roberts
   17. Karen Blyth
   18. Seth B. Coffelt
   19. Leo M. Carlin

   Reviewed by preLights

7. An updated and expanded characterization of the biological sciences academic job market

   This article has 8 authors:

   1. Brooklynn Flynn
   2. Ariangela J. Kozik
   3. You Cheng
   4. Ada K. Hagan
   5. Jennifer Ng
   6. Christopher T. Smith
   7. Amanda Haage
   8. Nafisa M. Jadavji

   Reviewed by preLights

8. Modeling transcriptional profiles of gene perturbation with deep neural network

   This article has 4 authors:

   1. Wenke Liu
   2. Xuya Wang
   3. D R Mani
   4. David Fenyö

   Reviewed by preLights

9. The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

   This article has 7 authors:

   1. Joelle Lo
   2. Katherine F. Vaeth
   3. Gurprit Bhardwaj
   4. Neelanjan Mukherjee
   5. Holger A. Russ
   6. Jeffrey K. Moore
   7. J. Matthew Taliaferro

   Reviewed by preLights

10. Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane

    This article has 17 authors:

    1. Einollah Sarikhani
    2. Vrund Patel
    3. Zhi Li
    4. Dhivya Pushpa Meganathan
    5. Keivan Rahmani
    6. Leah Sadr
    7. Ryan Hosseini
    8. Diether Visda
    9. Shivani Shukla
    10. Hamed Naghsh‐Nilchi
    11. Adarsh Balaji
    12. Gillian McMahon
    13. Shaoming Chen
    14. Johannes Schöneberg
    15. Colleen A. McHugh
    16. Lingyan Shi
    17. Zeinab Jahed

    Reviewed by preLights