eLife

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1. We couldn't get details of this article at this time:
   10.1101/2025.10.09.681358

2. We couldn't get details of this article at this time:
   10.1101/2025.09.23.677998

3. Spatially heterogeneous inhibition projects sequential activity onto unique neural subspaces

   This article has 3 authors:

   1. Andrew B Lehr
   2. Arvind Kumar
   3. Christian Tetzlaff

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This valuable study uses mathematical modeling and analysis to address the question of how neural circuits generate distinct low-dimensional, sequential neural dynamics that can change on fast, behaviorally relevant timescales. The authors propose a circuit model in which spatially heterogeneous inhibition constrains network dynamics to sequential activity on distinct neural subspaces and allows top-down sequence selection on fast timescales. The study convincingly demonstrates how this mechanism could operate and makes predictions about connectivity patterns and dynamics.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2025.08.18.670983

5. We couldn't get details of this article at this time:
   10.1101/2025.08.26.672310

6. We couldn't get details of this article at this time:
   10.1101/2025.09.01.673436

7. Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in cancer

   This article has 18 authors:

   1. Qian Wang
   2. Liping Li
   3. Lin You
   4. Shuai Wang
   5. Lei Han
   6. Bingnan Wang
   7. Liping Yao
   8. Yesu Addepalli
   9. Yong Lu
   10. Ilgen Mender
   11. Ann M Flusche
   12. Chiho Kim
   13. Nageswari Yarravarapu
   14. Andrew Lemoff
   15. Lawrence Lum
   16. Jerry W Shay
   17. Yonghao Yu
   18. Chuo Chen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study reports the development of the first tankyrase degrader and demonstrates its enhanced ability to inhibit β-catenin signaling compared to conventional tankyrase inhibitors. The evidence supporting the conclusions is comprehensive and convincing, based on rigorous biochemical and cellular analyses. The findings will be of broad interest to researchers studying Wnt signaling, protein degradation, and cancer biology.

   Reviewed by eLife

8. Genomic privacy risks in GWAS summary statistics

   This article has 3 authors:

   1. Ao Lan
   2. Yudi Pawitan
   3. Xia Shen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study provides a theoretical framework for quantifying privacy risk from publicly shared genome-wide association summary statistics. The findings reveal the conditions under which genotype reconstruction may become feasible, challenging long-held assumptions about personal data safety. While the evidence is solid, supported by clear mathematical derivations and simulations, validation on large empirical datasets would further strengthen the claims.

   Reviewed by eLife

9. Genomic privacy risks in GWAS summary statistics

   This article has 3 authors:

   1. Ao Lan
   2. Yudi Pawitan
   3. Xia Shen

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important study provides a theoretical framework for quantifying privacy risk from publicly shared genome-wide association summary statistics. The findings reveal the conditions under which genotype reconstruction may become feasible, challenging long-held assumptions about personal data safety. While the evidence is solid, supported by clear mathematical derivations and simulations, validation on large empirical datasets would further strengthen the claims.

   Reviewed by eLife

10. We couldn't get details of this article at this time:
    10.1101/2025.04.08.647705