eLife

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1. We couldn't get details of this article at this time:
   10.1101/2024.02.29.582862

2. Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner

   This article has 10 authors:

   1. Liana Senaldi
   2. Nora Hassan
   3. Sean Cullen
   4. Uthra Balaji
   5. Natalie Trigg
   6. Jinghua Gu
   7. Hailey Finkelstein
   8. Kathryn Phillips
   9. Colin Conine
   10. Matthew Smith-Raska

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This important mouse study shows that wild-type female progeny of Khdc3 mutants have abnormal gene expression relating to hepatic metabolism, which persists over multiple generations and passes through both female and male lineages. A role for small RNAs on this phenomenon is proposed, and evidence supporting the authors' claims is convincing. Further experiments are required to functionally validate the role of small RNAs in transmission of the phenotype. The work will be of interest to researchers in the field of DNA-independent mechanism of inheritance.

   Reviewed by eLife

3. A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development

   This article has 12 authors:

   1. Ashleigh Edwards
   2. Maurizio Junior Chiurazzi
   3. Anko Blaakmeer
   4. Ylenia Vittozzi
   5. Ashish Sharma
   6. Sanne Matton
   7. Valdeko Kruusvee
   8. Daniel Straub
   9. Giovanna Sessa
   10. Monica Carabelli
   11. Giorgio Morelli
   12. Stephan Wenkel

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     Through a genome-wide screen for functional alternative transcription start sites (TSS) in Arabidopsis, the authors provide evidence for widespread transcription of potential microproteins from previously annotated protein-coding genes. Functional analysis of AtHB2-miP, derived from the C-terminal region of transcription factor AtHB2 and predicted to form non-productive dimers with ATHB2, suggested that this microprotein could affect AtHB2 functions in shade responses, root growth, and iron homeostasis. The work is valuable as a case study of how new microproteins could act to modulate gene regulation in response to environmental change, but the focus on a single gene, the lack of precision in AtHB2-miP measurement and missing controls, and the relatively minor phenotypic effects mean that data supporting microprotein production as a vital regulatory strategy are incomplete.

   Reviewed by eLife

4. We couldn't get details of this article at this time:
   10.1101/2024.02.01.577722

5. We couldn't get details of this article at this time:
   10.1101/2023.11.09.566478

6. We couldn't get details of this article at this time:
   10.1101/2023.08.18.553913

7. We couldn't get details of this article at this time:
   10.1101/2023.07.26.550619

8. We couldn't get details of this article at this time:
   10.1101/2024.02.20.581165

9. We couldn't get details of this article at this time:
   10.1101/2023.03.29.534638

10. We couldn't get details of this article at this time:
    10.1101/2023.01.16.524234