Latest preprint reviews

1. Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain

   This article has 24 authors:

   1. Chi Zhang
   2. Qian Huang
   3. Neil C Ford
   4. Nathachit Limjunyawong
   5. Qing Lin
   6. Fei Yang
   7. Xiang Cui
   8. Ankit Uniyal
   9. Jing Liu
   10. Megha Mahabole
   11. Hua He
   12. Xue-Wei Wang
   13. Irina Duff
   14. Yiru Wang
   15. Jieru Wan
   16. Guangwu Zhu
   17. Srinivasa N Raja
   18. Hongpeng Jia
   19. Dazhi Yang
   20. Xinzhong Dong
   21. Xu Cao
   22. Scheffer C Tseng
   23. Shao-Qiu He
   24. Yun Guan

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The authors provide convincing data that identify a novel, non-opioid biologic from human birth tissue products with anti-nociceptive properties in a preclinical mouse model of surgical pain. This important study highlights the potential use of naturally derived biologics from human birth tissues as safe and sustainable pain treatment options that do not possess the adverse side effects associated with opioids and synthetic pharmaceuticals. Whether these results will translate to the clinic remains to be seen, nevertheless, these preclinical findings are promising.

   Reviewed by eLife, Arcadia Science

2. Human rod photoreceptor outer segments are supported by accessory inner segment structures

   This article has 9 authors:

   1. Tylor R. Lewis
   2. Natalia V. Klementieva
   3. Sebastien Phan
   4. Carson M. Castillo
   5. Keun-Young Kim
   6. Lauren Y. Cao
   7. Mark H. Ellisman
   8. Vadim Y. Arshavsky
   9. Oleg Alekseev

   Reviewed by Arcadia Science

3. A new class of receptors: Lipids regulate mammalian Gsα-stimulated adenylyl cyclase activities via their membrane anchors

   This article has 6 authors:

   1. Marius Landau
   2. Sherif Elsabbagh
   3. Harald Gross
   4. Adrian Fuchs
   5. Anita CF Schultz
   6. Joachim E Schultz

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript describes an important study of a new lipid-mediated regulation mechanism of adenylyl cyclases. The biochemical evidence provided is convincing and will trigger more research in this mechanism. This manuscript will be of interest to all scientists working on lipid regulation and adenylyl cyclases.

   Reviewed by eLife, Arcadia Science

4. Peptipedia v2.0: A peptide sequence database and user-friendly web platform. A major update

   This article has 13 authors:

   1. Gabriel Cabas-Mora
   2. Anamaría Daza
   3. Nicole Soto-García
   4. Valentina Garrido
   5. Diego Alvarez
   6. Marcelo Navarrete
   7. Lindybeth Sarmiento-Varón
   8. Julieta H. Sepúlveda Yañez
   9. Mehdi D. Davari
   10. Frederic Cadet
   11. Álvaro Olivera-Nappa
   12. Roberto Uribe-Paredes
   13. David Medina-Ortiz

   Reviewed by Arcadia Science

5. Raspberry Pi–powered imaging for plant phenotyping

   This article has 12 authors:

   1. Jose C. Tovar
   2. J. Steen Hoyer
   3. Andy Lin
   4. Allison Tielking
   5. Steven T. Callen
   6. S. Elizabeth Castillo
   7. Michael Miller
   8. Monica Tessman
   9. Noah Fahlgren
   10. James C. Carrington
   11. Dmitri A. Nusinow
   12. Malia A. Gehan

   Reviewed by Arcadia Science

6. Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

   This article has 10 authors:

   1. Timothy A. Crombie
   2. Moein Rajaei
   3. Ayush S. Saxena
   4. Lindsay M. Johnson
   5. Sayran Saber
   6. Robyn E. Tanny
   7. José Miguel Ponciano
   8. Erik C. Andersen
   9. Juannan Zhou
   10. Charles F. Baer

   Reviewed by Arcadia Science

7. Ciliary biology intersects autism and congenital heart disease

   This article has 10 authors:

   1. Nia Teerikorpi
   2. Micaela C. Lasser
   3. Sheng Wang
   4. Elina Kostyanovskaya
   5. Ethel Bader
   6. Nawei Sun
   7. Jeanselle Dea
   8. Tomasz J. Nowakowski
   9. A. Jeremy Willsey
   10. Helen Rankin Willsey

   Reviewed by Arcadia Science

8. The rich evolutionary history of the ROS metabolic arsenal shapes its mechanistic plasticity at the onset of metazoan regeneration

   This article has 8 authors:

   1. Aurore Vullien
   2. Aldine Amiel
   3. Loeiza Baduel
   4. Dilara Diken
   5. Cécile Renaud
   6. Michel Vervoort
   7. Eric Röttinger
   8. Eve Gazave

   Reviewed by Arcadia Science

9. Development of a highly active engineered PETase enzyme for polyester degradation

   This article has 7 authors:

   1. Shapla Bhattacharya
   2. Rossella Castagna
   3. Hajar Estiri
   4. Toms Upmanis
   5. Andrea Ricci
   6. Alfonso Gautieri
   7. Emilio Parisini

   Reviewed by Arcadia Science

10. Rapid protein evolution by few-shot learning with a protein language model

    This article has 12 authors:

    1. Kaiyi Jiang
    2. Zhaoqing Yan
    3. Matteo Di Bernardo
    4. Samantha R. Sgrizzi
    5. Lukas Villiger
    6. Alisan Kayabolen
    7. Byungji Kim
    8. Josephine K. Carscadden
    9. Masahiro Hiraizumi
    10. Hiroshi Nishimasu
    11. Jonathan S. Gootenberg
    12. Omar O. Abudayyeh

    Reviewed by Arcadia Science