Arcadia Science

Latest preprint reviews

1. A treasure trove of 1,034 actinomycete genomes

   This article has 13 authors:

   1. Tue Sparholt Jørgensen
   2. Omkar Mohite
   3. Eva B Sterndorff
   4. Maria Alvarez-Arevalo
   5. Kai Blin
   6. Thomas J Booth
   7. Pep Charusanti
   8. David Faurdal
   9. Troels Ø Hansen
   10. Matin Nuhamunada
   11. Anna-Sophie Mourched
   12. Bernhard Ø Palsson
   13. Tilmann Weber

   Reviewed by Arcadia Science

2. Temporal and spatial dynamics within the fungal microbiome of grape fermentation

   This article has 6 authors:

   1. Cristobal A. Onetto
   2. Chris M. Ward
   3. Steven Van Den Heuvel
   4. Laura Hale
   5. Kathleen Cuijvers
   6. Anthony R. Borneman

   Reviewed by Arcadia Science

3. Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma

   This article has 16 authors:

   1. Régis Joulia
   2. Franz Puttur
   3. Helen Stölting
   4. William J. Traves
   5. Lewis J. Entwistle
   6. Anastasia Voitovich
   7. Minerva Garcia Martín
   8. May Al-Sahaf
   9. Katie Bonner
   10. Elizabeth Scotney
   11. Philip L. Molyneaux
   12. Richard J. Hewitt
   13. Simone A. Walker
   14. Laura Yates
   15. Sejal Saglani
   16. Clare M. Lloyd

   Reviewed by Arcadia Science

4. A constraint-based framework to reconstruct interaction networks in microbial communities

   This article has 4 authors:

   1. Omid Oftadeh
   2. Asli Sahin
   3. Evangelia Vayena
   4. Vassily Hatzimanikatis

   Reviewed by Arcadia Science

5. CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans

   This article has 6 authors:

   1. Rachel Webster
   2. Maria Quintana
   3. Bin Yu
   4. Stacey Fluke
   5. Ran Kafri
   6. W. Brent Derry

   Reviewed by Arcadia Science

6. Evolution of novel sensory organs in fish with legs

   This article has 11 authors:

   1. Corey A.H. Allard
   2. Amy L. Herbert
   3. Stephanie P. Krueger
   4. Qiaoyi Liang
   5. Brittany L. Walsh
   6. Andrew L. Rhyne
   7. Allex N. Gourlay
   8. Agnese Seminara
   9. Maude W. Baldwin
   10. David M. Kingsley
   11. Nicholas W. Bellono

   Reviewed by Arcadia Science

7. Recording γ-secretase activity in living mouse brains

   This article has 9 authors:

   1. Steven S Hou
   2. Yuya Ikegawa
   3. Yeseo Kwon
   4. Natalia Wieckiewicz
   5. Mei CQ Houser
   6. Brianna Lundin
   7. Brian J Bacskai
   8. Oksana Berezovska
   9. Masato Maesako

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     Hou and colleagues describe the the use of a previously characterized FRET sensor for use in determining gamma secretase activity in the brain of living mice. In an approach that targeted the sensor to neurons, they observe patterns of fluorescent sensor readout suggesting clustered regions of secretase activity. These results once validated would be valuable in the field of Alzheimer's Disease research, yet further validation of the approach is required, as the current evidence provided is inadequate to support the conclusions.

   Reviewed by eLife, Arcadia Science

8. Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

   This article has 11 authors:

   1. Sasmita Panda
   2. Yahani P Jayasinghe
   3. Dhananjay D Shinde
   4. Emilio Bueno
   5. Amanda Stastny
   6. Blake P Bertrand
   7. Sujata S Chaudhari
   8. Tammy Kielian
   9. Felipe Cava
   10. Donald R Ronning
   11. Vinai C Thomas

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     In this useful study, the authors present convincing evidence linking the enzyme D-alanine-D-alanine ligase (Ddl), crucial for cell wall fortification, to organic acid exposure in Staphylococcus aureus. While it's established that organic acids impede bacterial growth, the researchers reveal a novel coping mechanism where S. aureus maintains elevated levels of D-alanine, the substrate for Ddl, to counteract this inhibition. This discovery illuminates a bacterial strategy for organic acid tolerance, offering new insights for microbiologists and potentially informing future antimicrobial approaches.

   Reviewed by eLife, Arcadia Science

9. Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

   This article has 6 authors:

   1. Ken-ichiro F Kamei
   2. Koseki J Kobayashi-Kirschvink
   3. Takashi Nozoe
   4. Hidenori Nakaoka
   5. Miki Umetani
   6. Yuichi Wakamoto

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This paper reports the fundamental finding of how Raman spectral patterns correlate with proteome profiles using Raman spectra of E. coli cells from different physiological conditions and found global stoichiometric regulation on proteomes. The authors' findings provide compelling evidence that stoichiometric regulation of proteomes is general through analysis of both bacterial and human cells. In the future, similar methodology can be applied on various tissue types and microbial species for studying proteome composition with Raman spectral patterns.

   Reviewed by eLife, Arcadia Science

10. Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

    This article has 2 authors:

    1. Sarah Poirier
    2. Fabrice Jean-Pierre

    Reviewed by Arcadia Science