Pharmacology and Toxicology

  1. An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity

    1. Naoya Kitamura
    2. Michael Dominic Sacco
    3. Chunlong Ma
    4. Yanmei Hu
    5. Julia Alma Townsend
    6. Xiangzhi Meng
    7. Fushun Zhang
    8. Xiujun Zhang
    9. Adis Kukuljac
    10. Michael Thomas Marty
    11. David Schultz
    12. Sara Cherry
    13. Yan Xiang
    14. Yu Chen
    15. Jun Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Genetic determinants of COVID-19 drug efficacy revealed by genome-wide CRISPR screens

    1. Wei Jiang
    2. Ailing Yang
    3. Jingchuan Ma
    4. Dawei Lv
    5. Mingxian Liu
    6. Liang Xu
    7. Chao Wang
    8. Zhengjin He
    9. Shuo Chen
    10. Jie Zhao
    11. Shishuang Chen
    12. Qi Jiang
    13. Yankai Chu
    14. Lin Shan
    15. Zhaocai Zhou
    16. Yun Zhao
    17. Gang Long
    18. Hai Jiang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

    1. Krzysztof Pyrć
    2. Aleksandra Milewska
    3. Emilia Barreto Duran
    4. Paweł Botwina
    5. Rui Lopes
    6. Alejandro Arenas-Pinto
    7. Moutaz Badr
    8. Ryan Mellor
    9. Tammy L. Kalber
    10. Delmiro Fernandes-Reyes
    11. Andreas G. Schätzlein
    12. Ijeoma F. Uchegbu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2

    1. Zhijian Xu
    2. Danrong Shi
    3. Jian-Bao Han
    4. Yun Ling
    5. Xiangrui Jiang
    6. Xiangyun Lu
    7. Chuan Li
    8. Likun Gong
    9. Guangbo Ge
    10. Yani Zhang
    11. Yi Zang
    12. Tian-Zhang Song
    13. Xiao-Li Feng
    14. Ren-Rong Tian
    15. Jia Ji
    16. Miaojin Zhu
    17. Nanping Wu
    18. Chunhui Wu
    19. Zhen Wang
    20. Yechun Xu
    21. Cheng Peng
    22. Min Zheng
    23. Junling Yang
    24. Feifei Du
    25. Junliang Wu
    26. Peipei Wang
    27. Jingshan Shen
    28. Jianliang Zhang
    29. Yong-Tang Zheng
    30. Hangping Yao
    31. Weiliang Zhu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Nucleotide Analogues as Inhibitors of Viral Polymerases

    1. Jingyue Ju
    2. Shiv Kumar
    3. Xiaoxu Li
    4. Steffen Jockusch
    5. James J. Russo

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

    1. Ana C. Puhl
    2. Ethan J. Fritch
    3. Thomas R. Lane
    4. Longping V. Tse
    5. Boyd L. Yount
    6. Carolina Q. Sacramento
    7. Natalia Fintelman-Rodrigues
    8. Tatyana Almeida Tavella
    9. Fabio Trindade Maranhão Costa
    10. Stuart Weston
    11. James Logue
    12. Matthew Frieman
    13. Lakshmanane Premkumar
    14. Kenneth H. Pearce
    15. Brett L. Hurst
    16. Carolina Horta Andrade
    17. James A. Levi
    18. Nicole J. Johnson
    19. Samantha C. Kisthardt
    20. Frank Scholle
    21. Thiago Moreno L. Souza
    22. Nathaniel John Moorman
    23. Ralph S. Baric
    24. Peter B. Madrid
    25. Sean Ekins

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Discovery of rhodomyrtone as a broad-spectrum antiviral inhibitor with anti-SARS-CoV-2 activity

    1. Wei Tang
    2. Jing Lu
    3. Qiao-Yun Song
    4. Man-Mei Li
    5. Li-Feng Chen
    6. Li-Jun Hu
    7. Shao-Min Yang
    8. Dong-Mei Zhang
    9. Ying Wang
    10. Yao-Lan Li
    11. Wen-Cai Ye

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. In Vitro Efficacy of “Essential Iodine Drops” Against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)

    1. Köntös Zoltán

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19

    1. Britton Boras
    2. Rhys M. Jones
    3. Brandon J. Anson
    4. Dan Arenson
    5. Lisa Aschenbrenner
    6. Malina A. Bakowski
    7. Nathan Beutler
    8. Joseph Binder
    9. Emily Chen
    10. Heather Eng
    11. Holly Hammond
    12. Jennifer Hammond
    13. Robert E. Haupt
    14. Robert Hoffman
    15. Eugene P. Kadar
    16. Rob Kania
    17. Emi Kimoto
    18. Melanie G. Kirkpatrick
    19. Lorraine Lanyon
    20. Emma K. Lendy
    21. Jonathan R. Lillis
    22. James Logue
    23. Suman A. Luthra
    24. Chunlong Ma
    25. Stephen W. Mason
    26. Marisa E. McGrath
    27. Stephen Noell
    28. R. Scott Obach
    29. Matthew N. O’Brien
    30. Rebecca O’Connor
    31. Kevin Ogilvie
    32. Dafydd Owen
    33. Martin Pettersson
    34. Matthew R Reese
    35. Thomas F. Rogers
    36. Michelle I. Rossulek
    37. Jean G. Sathish
    38. Norimitsu Shirai
    39. Claire Steppan
    40. Martyn Ticehurst
    41. Lawrence W. Updyke
    42. Stuart Weston
    43. Yuao Zhu
    44. Jun Wang
    45. Arnab K. Chatterjee
    46. Andrew D. Mesecar
    47. Matthew B. Frieman
    48. Annaliesa S. Anderson
    49. Charlotte Allerton

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

    1. Yan Li
    2. Jinyong Zhang
    3. Ning Wang
    4. Haibo Li
    5. Yun Shi
    6. Gang Guo
    7. Kaiyun Liu
    8. Hao Zeng
    9. Quanming Zou

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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