Pharmacology and Toxicology

  1. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

    1. Ana C. Puhl
    2. Ethan J. Fritch
    3. Thomas R. Lane
    4. Longping V. Tse
    5. Boyd L. Yount
    6. Carolina Q. Sacramento
    7. Natalia Fintelman-Rodrigues
    8. Tatyana Almeida Tavella
    9. Fabio Trindade Maranhão Costa
    10. Stuart Weston
    11. James Logue
    12. Matthew Frieman
    13. Lakshmanane Premkumar
    14. Kenneth H. Pearce
    15. Brett L. Hurst
    16. Carolina Horta Andrade
    17. James A. Levi
    18. Nicole J. Johnson
    19. Samantha C. Kisthardt
    20. Frank Scholle
    21. Thiago Moreno L. Souza
    22. Nathaniel John Moorman
    23. Ralph S. Baric
    24. Peter B. Madrid
    25. Sean Ekins

    Reviewed by ScreenIT

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  2. Discovery of rhodomyrtone as a broad-spectrum antiviral inhibitor with anti-SARS-CoV-2 activity

    1. Wei Tang
    2. Jing Lu
    3. Qiao-Yun Song
    4. Man-Mei Li
    5. Li-Feng Chen
    6. Li-Jun Hu
    7. Shao-Min Yang
    8. Dong-Mei Zhang
    9. Ying Wang
    10. Yao-Lan Li
    11. Wen-Cai Ye

    Reviewed by ScreenIT

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  3. In Vitro Efficacy of “Essential Iodine Drops” Against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)

    1. Köntös Zoltán

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  4. Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19

    1. Britton Boras
    2. Rhys M. Jones
    3. Brandon J. Anson
    4. Dan Arenson
    5. Lisa Aschenbrenner
    6. Malina A. Bakowski
    7. Nathan Beutler
    8. Joseph Binder
    9. Emily Chen
    10. Heather Eng
    11. Holly Hammond
    12. Jennifer Hammond
    13. Robert E. Haupt
    14. Robert Hoffman
    15. Eugene P. Kadar
    16. Rob Kania
    17. Emi Kimoto
    18. Melanie G. Kirkpatrick
    19. Lorraine Lanyon
    20. Emma K. Lendy
    21. Jonathan R. Lillis
    22. James Logue
    23. Suman A. Luthra
    24. Chunlong Ma
    25. Stephen W. Mason
    26. Marisa E. McGrath
    27. Stephen Noell
    28. R. Scott Obach
    29. Matthew N. O’Brien
    30. Rebecca O’Connor
    31. Kevin Ogilvie
    32. Dafydd Owen
    33. Martin Pettersson
    34. Matthew R Reese
    35. Thomas F. Rogers
    36. Michelle I. Rossulek
    37. Jean G. Sathish
    38. Norimitsu Shirai
    39. Claire Steppan
    40. Martyn Ticehurst
    41. Lawrence W. Updyke
    42. Stuart Weston
    43. Yuao Zhu
    44. Jun Wang
    45. Arnab K. Chatterjee
    46. Andrew D. Mesecar
    47. Matthew B. Frieman
    48. Annaliesa S. Anderson
    49. Charlotte Allerton

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  5. Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

    1. Yan Li
    2. Jinyong Zhang
    3. Ning Wang
    4. Haibo Li
    5. Yun Shi
    6. Gang Guo
    7. Kaiyun Liu
    8. Hao Zeng
    9. Quanming Zou

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  6. CETSA MS Profiling for a Comparative Assessment of FDA-Approved Antivirals Repurposed for COVID-19 Therapy Identifies TRIP13 as a Remdesivir Off-Target

    1. Tomas Friman
    2. Alexey Chernobrovkin
    3. Daniel Martinez Molina
    4. Laurence Arnold

    Reviewed by ScreenIT

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  7. In Vitro Activity of Itraconazole Against SARS-CoV-2

    1. Ellen Van Damme
    2. Sandra De Meyer
    3. Denisa Bojkova
    4. Sandra Ciesek
    5. Jindrich Cinatl
    6. Steven De Jonghe
    7. Dirk Jochmans
    8. Pieter Leyssen
    9. Christophe Buyck
    10. Johan Neyts
    11. Marnix Van Loock

    Reviewed by ScreenIT

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  8. The in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication

    1. Madeline Loffredo
    2. Hector Lucero
    3. Da-Yuan Chen
    4. Aoife O’Connell
    5. Simon Bergqvist
    6. Ahmad Munawar
    7. Asanga Bandara
    8. Steff De Graef
    9. Stephen D. Weeks
    10. Florian Douam
    11. Mohsan Saeed
    12. Ali H. Munawar

    Reviewed by ScreenIT

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  9. The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models

    1. Scott P. Davies
    2. Courtney J. Mycroft-West
    3. Isabel Pagani
    4. Harriet J. Hill
    5. Yen-Hsi Chen
    6. Richard Karlsson
    7. Ieva Bagdonaite
    8. Scott E. Guimond
    9. Zania Stamataki
    10. Marcelo Andrade De Lima
    11. Jeremy E. Turnbull
    12. Zhang Yang
    13. Elisa Vicenzi
    14. Mark A. Skidmore
    15. Farhat L. Khanim
    16. Alan Richardson

    Reviewed by ScreenIT

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  10. Interactions of anti-COVID-19 drug candidates with multispecific ABC and OATP drug transporters

    1. Ágnes Telbisz
    2. Csilla Ambrus
    3. Orsolya Mózner
    4. Edit Szabó
    5. György Várady
    6. Éva Bakos
    7. Balázs Sarkadi
    8. Csilla Özvegy-Laczka

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