Pharmacology and Toxicology

  1. CETSA MS Profiling for a Comparative Assessment of FDA-Approved Antivirals Repurposed for COVID-19 Therapy Identifies TRIP13 as a Remdesivir Off-Target

    1. Tomas Friman
    2. Alexey Chernobrovkin
    3. Daniel Martinez Molina
    4. Laurence Arnold

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. In vitro activity of itraconazole against SARS‐CoV‐2

    1. Ellen Van Damme
    2. Sandra De Meyer
    3. Denisa Bojkova
    4. Sandra Ciesek
    5. Jindrich Cinatl
    6. Steven De Jonghe
    7. Dirk Jochmans
    8. Pieter Leyssen
    9. Christophe Buyck
    10. Johan Neyts
    11. Marnix Van Loock

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. The in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication

    1. Madeline Loffredo
    2. Hector Lucero
    3. Da-Yuan Chen
    4. Aoife O’Connell
    5. Simon Bergqvist
    6. Ahmad Munawar
    7. Asanga Bandara
    8. Steff De Graef
    9. Stephen D. Weeks
    10. Florian Douam
    11. Mohsan Saeed
    12. Ali H. Munawar

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models

    1. Scott P. Davies
    2. Courtney J. Mycroft-West
    3. Isabel Pagani
    4. Harriet J. Hill
    5. Yen-Hsi Chen
    6. Richard Karlsson
    7. Ieva Bagdonaite
    8. Scott E. Guimond
    9. Zania Stamataki
    10. Marcelo Andrade De Lima
    11. Jeremy E. Turnbull
    12. Zhang Yang
    13. Elisa Vicenzi
    14. Mark A. Skidmore
    15. Farhat L. Khanim
    16. Alan Richardson

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters

    1. Ágnes Telbisz
    2. Csilla Ambrus
    3. Orsolya Mózner
    4. Edit Szabó
    5. György Várady
    6. Éva Bakos
    7. Balázs Sarkadi
    8. Csilla Özvegy-Laczka

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Ivermectin repurposing for COVID-19 therapy: Safety and pharmacokinetic assessment of a novel nasal spray formulation in a pig model

    1. J. Errecalde
    2. A. Lifschitz
    3. G. Vecchioli
    4. L. Ceballos
    5. F. Errecalde
    6. M. Ballent
    7. G. Marín
    8. M. Daniele
    9. E. Turic
    10. E. Spitzer
    11. F. Toneguzzo
    12. S. Gold
    13. A. Krolewiecki
    14. L. Alvarez
    15. C. Lanusse

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Ozone exposure upregulates the expression of host susceptibility protein TMPRSS2 to SARS-CoV-2

    1. Thao Vo
    2. Kshitiz Paudel
    3. Ishita Choudhary
    4. Sonika Patial
    5. Yogesh Saini

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. In vitro efficacy of Artemisinin-based treatments against SARS-CoV-2

    1. Kerry Gilmore
    2. Yuyong Zhou
    3. Santseharay Ramirez
    4. Long V. Pham
    5. Ulrik Fahnøe
    6. Shan Feng
    7. Anna Offersgaard
    8. Jakob Trimpert
    9. Jens Bukh
    10. Klaus Osterrieder
    11. Judith M. Gottwein
    12. Peter H. Seeberger

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion

    1. Tai Young Kim
    2. Sangeun Jeon
    3. Youngho Jang
    4. Lizaveta Gotina
    5. Joungha Won
    6. Yeon Ha Ju
    7. Sunpil Kim
    8. Minwoo Wendy Jang
    9. Woojin Won
    10. Mingu Gordon Park
    11. Ae Nim Pae
    12. Sunkyu Han
    13. Seungtaek Kim
    14. C. Justin Lee

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro

    1. Guankui Wang
    2. Hanmant Gaikwad
    3. Mary McCarthy
    4. Mercedes Gonzalez-Juarrero
    5. Yue Li
    6. Michael Armstrong
    7. Nichole Reisdorph
    8. Thomas Morrison
    9. Dmitri Simberg

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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