Pharmacology and Toxicology

  1. SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

    1. Krzysztof Pyrć
    2. Aleksandra Milewska
    3. Emilia Barreto Duran
    4. Paweł Botwina
    5. Rui Lopes
    6. Alejandro Arenas-Pinto
    7. Moutaz Badr
    8. Ryan Mellor
    9. Tammy L. Kalber
    10. Delmiro Fernandes-Reyes
    11. Andreas G. Schätzlein
    12. Ijeoma F. Uchegbu

    Reviewed by ScreenIT

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  2. Nelfinavir was predicted to be a potential inhibitor of 2019-nCov main protease by an integrative approach combining homology modelling, molecular docking and binding free energy calculation

    1. Zhijian Xu
    2. Cheng Peng
    3. Yulong Shi
    4. Zhengdan Zhu
    5. Kaijie Mu
    6. Xiaoyu Wang
    7. Weiliang Zhu

    Reviewed by ScreenIT

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  3. Nucleotide Analogues as Inhibitors of Viral Polymerases

    1. Jingyue Ju
    2. Shiv Kumar
    3. Xiaoxu Li
    4. Steffen Jockusch
    5. James J. Russo

    Reviewed by ScreenIT

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  4. Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

    1. Ana C. Puhl
    2. Ethan James Fritch
    3. Thomas R. Lane
    4. Longping V. Tse
    5. Boyd L. Yount
    6. Carol Queiroz Sacramento
    7. Tatyana Almeida Tavella
    8. Fabio Trindade Maranhão Costa
    9. Stuart Weston
    10. James Logue
    11. Matthew Frieman
    12. Lakshmanane Premkumar
    13. Kenneth H. Pearce
    14. Brett L. Hurst
    15. Carolina Horta Andrade
    16. James A. Levi
    17. Nicole J. Johnson
    18. Samantha C. Kisthardt
    19. Frank Scholle
    20. Thiago Moreno L. Souza
    21. Nathaniel John Moorman
    22. Ralph S. Baric
    23. Peter Madrid
    24. Sean Ekins

    Reviewed by ScreenIT

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  5. Discovery of rhodomyrtone as a broad-spectrum antiviral inhibitor with anti-SARS-CoV-2 activity

    1. Wei Tang
    2. Jing Lu
    3. Qiao-Yun Song
    4. Man-Mei Li
    5. Li-Feng Chen
    6. Li-Jun Hu
    7. Shao-Min Yang
    8. Dong-Mei Zhang
    9. Ying Wang
    10. Yao-Lan Li
    11. Wen-Cai Ye

    Reviewed by ScreenIT

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  6. In Vitro Efficacy of “Essential Iodine Drops” Against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)

    1. Köntös Zoltán

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  7. Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19

    1. Britton Boras
    2. Rhys M. Jones
    3. Brandon J. Anson
    4. Dan Arenson
    5. Lisa Aschenbrenner
    6. Malina A. Bakowski
    7. Nathan Beutler
    8. Joseph Binder
    9. Emily Chen
    10. Heather Eng
    11. Holly Hammond
    12. Jennifer Hammond
    13. Robert E. Haupt
    14. Robert Hoffman
    15. Eugene P. Kadar
    16. Rob Kania
    17. Emi Kimoto
    18. Melanie G. Kirkpatrick
    19. Lorraine Lanyon
    20. Emma K. Lendy
    21. Jonathan R. Lillis
    22. James Logue
    23. Suman A. Luthra
    24. Chunlong Ma
    25. Stephen W. Mason
    26. Marisa E. McGrath
    27. Stephen Noell
    28. R. Scott Obach
    29. Matthew N. O’Brien
    30. Rebecca O’Connor
    31. Kevin Ogilvie
    32. Dafydd Owen
    33. Martin Pettersson
    34. Matthew R Reese
    35. Thomas F. Rogers
    36. Michelle I. Rossulek
    37. Jean G. Sathish
    38. Norimitsu Shirai
    39. Claire Steppan
    40. Martyn Ticehurst
    41. Lawrence W. Updyke
    42. Stuart Weston
    43. Yuao Zhu
    44. Jun Wang
    45. Arnab K. Chatterjee
    46. Andrew D. Mesecar
    47. Matthew B. Frieman
    48. Annaliesa S. Anderson
    49. Charlotte Allerton

    Reviewed by ScreenIT

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  8. Therapeutic Drugs Targeting 2019-nCoV Main Protease by High-Throughput Screening

    1. Yan Li
    2. Jinyong Zhang
    3. Ning Wang
    4. Haibo Li
    5. Yun Shi
    6. Gang Guo
    7. Kaiyun Liu
    8. Hao Zeng
    9. Quanming Zou

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. CETSA ® MS profiling for a comparative assessment of FDA approved antivirals repurposed for COVID-19 therapy identifies Trip13 as a Remdesivir off-target

    1. Tomas Friman
    2. Alexey Chernobrovkin
    3. Daniel Martinez Molina
    4. Laurence Arnold

    Reviewed by ScreenIT

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  10. In Vitro Activity of Itraconazole Against SARS-CoV-2

    1. Ellen Van Damme
    2. Sandra De Meyer
    3. Denisa Bojkova
    4. Sandra Ciesek
    5. Jindrich Cinatl
    6. Steven De Jonghe
    7. Dirk Jochmans
    8. Pieter Leyssen
    9. Christophe Buyck
    10. Johan Neyts
    11. Marnix Van Loock

    Reviewed by ScreenIT

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