Neuroscience

eLife Assessment

This study uses a Bayesian framework to characterize latent brain state dynamics associated with memory encoding and performance in children, as measured with functional magnetic resonance imaging. The novelty of the approach offers valuable insights into memory-related brain activity, but the consideration of developmental changes in memory and brain dynamics, and the evidence to support the proposed mapping between specific states and distinct aspects of memory, are incomplete. This work will be of interest to researchers interested in cognitive neuroscience and the development of memory.

eLife Assessment

This study presents a well-executed investigation into how the olfactory system disconnects from the environment during sleep and anesthesia, identifying a potential gating mechanism at the earliest synaptic stages of the olfactory bulb. The findings are important, as they challenge current theories by demonstrating that sensory gating occurs in non-thalamic pathways even under controlled airflow conditions. The strength of evidence is solid, supported by rigorous multimodal recordings, although the reliance on anesthetic models to draw conclusions about natural sleep is a limitation that requires further contextualization.

eLife Assessment

The present work provides new insights into detailed brain morphology. Using state-of-the-art methods, it provides compelling evidence for the relevance of sucal morphology for the precise localization of brain function. The fundamental findings have great relevance for the fields of imaging neuroscience and individualized medicine as ever-improving techniques improve precision to the point where individual brain anatomy is taking centre stage.