Neuroscience

High-precision registration between zebrafish brain atlases using symmetric diffeomorphic normalization

1. Gregory D. Marquart
2. Kathryn M. Tabor
3. Eric J. Horstick
4. Mary Brown
5. Alexandra K. Geoca
6. Nicholas F. Polys
7. Damian Dalle Nogare
8. Harold A. Burgess

Reviewed by GigaScience

The Healthy Brain Network Serial Scanning Initiative: a resource for evaluating inter-individual differences and their reliabilities across scan conditions and sessions

1. David O'Connor
2. Natan Vega Potler
3. Meagan Kovacs
4. Ting Xu
5. Lei Ai
6. John Pellman
7. Tamara Vanderwal
8. Lucas C. Parra
9. Samantha Cohen
10. Satrajit Ghosh
11. Jasmine Escalera
12. Natalie Grant-Villegas
13. Yael Osman
14. Anastasia Bui
15. R. Cameron Craddock
16. Michael P. Milham

Reviewed by GigaScience

The preprocessed connectomes project repository of manually corrected skull-stripped T1-weighted anatomical MRI data

1. Benjamin Puccio
2. James P Pooley
3. John S Pellman
4. Elise C Taverna
5. R Cameron Craddock

Reviewed by GigaScience

A data repository and analysis framework for spontaneous neural activity recordings in developing retina

1. Stephen John Eglen
2. Michael Weeks
3. Mark Jessop
4. Jennifer Simonotto
5. Tom Jackson
6. Evelyne Sernagor

Reviewed by GigaScience

Population modeling with machine learning can enhance measures of mental health

1. Kamalaker Dadi
2. Gaël Varoquaux
3. Josselin Houenou
4. Danilo Bzdok
5. Bertrand Thirion
6. Denis Engemann

Reviewed by GigaScience

Astroglial CD38 regulates social memory and synapse formation through SPARCL1 in the medial prefrontal cortex

1. Tsuyoshi Hattori
2. Stanislav M Cherepanov
3. Ryo Sakaga
4. Jureepon Roboon
5. Dinh Thi Nguyen
6. Hiroshi Ishii
7. Mika Takarada-Iemata
8. Takumi Nishiuchi
9. Takayuki Kannon
10. Kazuyoshi Hosomichi
11. Atsushi Tajima
12. Yasuhiko Yamamoto
13. Hiroshi Okamoto
14. Akira Sugawara
15. Haruhiro Higashida
16. Osamu Hori

Reviewed by Review Commons

BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking

1. Christopher J Gabriel
2. Zachary Zeidler
3. Benita Jin
4. Changliang Guo
5. Caitlin M Goodpaster
6. Adrienne Q Kashay
7. Anna Wu
8. Molly Delaney
9. Jovian Cheung
10. Lauren E DiFazio
11. Melissa J Sharpe
12. Daniel Aharoni
13. Scott A Wilke
14. Laura A DeNardo

• Curated by eLife

  Evaluation Summary:

  This paper is of potential interest to researchers performing animal behavioral quantification with computer vision tools. The manuscript introduces 'BehaviorDEPOT', a MATLAB application and GUI intended to facilitate quantification and analysis of freezing behavior from behavior movies, along with several other classifiers based on movement statistics calculated from animal pose data. The paper describes how the tool can be applied to several specific types of experiments, and emphasizes the ease of use - particularly for groups without experience in coding or behavioral quantification. While these aims are laudable, and the software is relatively easy to use, further improvements to make the tool more automated would substantially broaden the likely user base.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Reorganization of postmitotic neuronal chromatin accessibility for maturation of serotonergic identity

1. Xinrui L Zhang
2. William C Spencer
3. Nobuko Tabuchi
4. Meagan M Kitt
5. Evan S Deneris

• Curated by eLife

  Evaluation Summary:

  This paper will be of interest to developmental biologists who study the gene regulatory mechanisms necessary for induction and maintenance of postmitotic neuronal identity. The study generated a useful resource of genomic data and provided new insights into the dynamic regulation of accessible chromatin regions in post-mitotic serotonin (5-HT) neurons of the mouse hindbrain. This work proposes two transcription factors (Pet1, Lmx1b) as necessary for establishment and maintenance of accessible chromatin regions in serotonin (5-HT) neurons. The study is a major technical achievement but some of the central claims are not yet fully demonstrated.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

Reviewed by eLife

Magnetic stimulation allows focal activation of the mouse cochlea

1. Jae-Ik Lee
2. Richard Seist
3. Stephen McInturff
4. Daniel J Lee
5. M Christian Brown
6. Konstantina M Stankovic
7. Shelley Fried

• Curated by eLife

  Evaluation Summary:

  This study provides a demonstration that magnetic stimulation of the cochlea is feasible and suggests it could be more precise than electrical stimulation for cochlear implants. The conclusions of the paper are mostly well supported by data, but some aspects of the experimental procedure, the neuronal response acquisition, and the data analysis need to be clarified and extended.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife

Generation of a CRF1-Cre transgenic rat and the role of central amygdala CRF1 cells in nociception and anxiety-like behavior

1. Marcus M Weera
2. Abigail E Agoglia
3. Eliza Douglass
4. Zhiying Jiang
5. Shivakumar Rajamanickam
6. Rosetta S Shackett
7. Melissa A Herman
8. Nicholas J Justice
9. Nicholas W Gilpin

• Curated by eLife

  Evaluation Summary:

  This manuscript describes, characterizes, and validates a novel transgenic tool that will be useful for the study of stress neurobiology and the function of the stress-related neuropeptide corticotropin releasing factor. This tool will be especially relevant to the study of stress and related fields, such as addiction, in which rats are a critical model system. There is comprehensive histochemical and functional validation of the novel rat that broadly supports its proposed utility for visualizing and providing access to central amygdala CRF1 receptor-expressing neurons.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 and Reviewer #3 agreed to share their name with the authors.)

Reviewed by eLife