Neurology

Steroid‐Responsive Encephalitis in Coronavirus Disease 2019

1. Andrea Pilotto
2. Silvia Odolini
3. Stefano Masciocchi
4. Agnese Comelli
5. Irene Volonghi
6. Stefano Gazzina
7. Sara Nocivelli
8. Alessandro Pezzini
9. Emanuele Focà
10. Arnaldo Caruso
11. Matilde Leonardi
12. Maria P. Pasolini
13. Roberto Gasparotti
14. Francesco Castelli
15. Nicholas J. Ashton
16. Kaj Blennow
17. Henrik Zetterberg
18. Alessandro Padovani

Reviewed by ScreenIT

Acute myelitis after SARS-CoV-2 infection: a case report

1. Kang Zhao
2. Jucun Huang
3. Dan Dai
4. Yuwei Feng
5. Liming Liu
6. Shuke Nie

Reviewed by ScreenIT

The evaluation of sleep disturbances for Chinese frontline medical workers under the outbreak of COVID-19

1. Jing Qi
2. Jing Xu
3. Bo-Zhi Li
4. Jin-Sha Huang
5. Yuan Yang
6. Zhen-Tao Zhang
7. Dong-Ai Yao
8. Qun-Hui Liu
9. Min Jia
10. Dao-Kai Gong
11. Xiao-Hong Ni
12. Qi-Mei Zhang
13. Fu-Rong Shang
14. Nian Xiong
15. Chun-Li Zhu
16. Tao Wang
17. Xi Zhang

Reviewed by ScreenIT

Conscious processing of global and local auditory irregularities causes differentiated heartbeat-evoked responses

1. Diego Candia-Rivera
2. Federico Raimondo
3. Pauline Pérez
4. Lionel Naccache
5. Catherine Tallon-Baudry
6. Jacobo D Sitt

• Curated by eLife

  eLife assessment

  Motivated by previous demonstrations that cognitive modulation of heart beat evoked responses (HER) might distinguish minimally consciousness state and unresponsive wakefulness syndrome patients, the present work sought to determine whether contextual processing of auditory regularities (local-global paradigm) differentially affects HER in these patient groups. The results provide preliminary evidence for the usefulness of EEG and oddball paradigms in informing diagnosis of the state of consciousness. This paper will be of interest to those researchers studying signs of consciousness in post-comatose patients and more broadly to those studying brain-body interactions. However, some aspects of the study design and data analysis need to be clarified, particularly as these affect the conclusions that can be drawn.

Reviewed by eLife

Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer’s disease and neurodegeneration stratified by sex

1. Irene Cumplido-Mayoral
2. Marina García-Prat
3. Grégory Operto
4. Carles Falcon
5. Mahnaz Shekari
6. Raffaele Cacciaglia
7. Marta Milà-Alomà
8. Luigi Lorenzini
9. Silvia Ingala
10. Alle Meije Wink
11. Henk JMM Mutsaerts
12. Carolina Minguillón
13. Karine Fauria
14. José Luis Molinuevo
15. Sven Haller
16. Gael Chetelat
17. Adam Waldman
18. Adam J Schwarz
19. Frederik Barkhof
20. Ivonne Suridjan
21. Gwendlyn Kollmorgen
22. Anna Bayfield
23. Henrik Zetterberg
24. Kaj Blennow
25. Marc Suárez-Calvet
26. Verónica Vilaplana
27. Juan Domingo Gispert
28. ALFA study
29. EPAD study
30. ADNI study
31. OASIS study

• Curated by eLife

  eLife assessment

  The study has some significance for the field of dementia research and neurodegenerative diseases more broadly. Using the brain-age paradigm, the main findings are that having an older-appearing brain is associated with more advanced stages of amyloid and tau pathology, higher white matter hyperintensities, higher plasma NfL and carrying the APOE 34 allele. Findings were broadly similar in cognitively normal people and people with mild cognitive impairment and the evidence for these findings is convincing. Although sex differences are emphasized, the evidence for this is generally incomplete.

Reviewed by eLife

Monoallelic CRMP1 gene variants cause neurodevelopmental disorder

1. Ethiraj Ravindran
2. Nobuto Arashiki
3. Lena-Luise Becker
4. Kohtaro Takizawa
5. Jonathan Lévy
6. Thomas Rambaud
7. Konstantin L Makridis
8. Yoshio Goshima
9. Na Li
10. Maaike Vreeburg
11. Bénédicte Demeer
12. Achim Dickmanns
13. Alexander PA Stegmann
14. Hao Hu
15. Fumio Nakamura
16. Angela M Kaindl

• Curated by eLife

  Evaluation Summary:

  This manuscript describes de novo dominant toxic mutations in CRMP1 in 3 probands with a shared neurodevelopmental phenotype. The authors show that the mutations lead to reduced protein production from recombinant expression and that the mutations correlate with shorter neurites in cultured cells. This is the first report of mutations in CRMP1 in humans, encoding a cytoskeletal regulator protein. The results could have implications for physicians, geneticists, neurodevelopmental scientists, and cell biologists.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

Reviewed by eLife

Clearing the Fog: a Systematic Review on Cognitive Dysfunction in COVID-19

1. Nicole Butardo
2. Mikaela Frances Coronel
3. Alanna Marie Dino
4. Tiffany Ritz Mendoza
5. Oliver Kyle Sto. Domingo
6. Zypher Jude Regencia
7. Jacqueline Dominguez
8. Emmanuel Baja
9. Antonio Ligsay

Reviewed by ScreenIT

The negative impact of COVID-19 on working memory revealed using a rapid online quiz

1. Heidi A. Baseler
2. Murat Aksoy
3. Abayomi Salawu
4. Angela Green
5. Aziz U. R. Asghar

Reviewed by ScreenIT

Neuropathic symptoms with SARS-CoV-2 vaccination

1. Farinaz Safavi
2. Lindsey Gustafson
3. Brian Walitt
4. Tanya Lehky
5. Sara Dehbashi
6. Amanda Wiebold
7. Yair Mina
8. Susan Shin
9. Baohan Pan
10. Michael Polydefkis
11. Anne Louise Oaklander
12. Avindra Nath

Reviewed by ScreenIT

Decreased cerebral blood flow in non-hospitalized adults who self-isolated due to COVID-19

1. William S.H. Kim
2. Xiang Ji
3. Eugenie Roudaia
4. J. Jean Chen
5. Asaf Gilboa
6. Allison Sekuler
7. Fuqiang Gao
8. Zhongmin Lin
9. Aravinthan Jegatheesan
10. Mario Masellis
11. Maged Goubran
12. Jennifer S. Rabin
13. Benjamin Lam
14. Ivy Cheng
15. Robert Fowler
16. Chris Heyn
17. Sandra E. Black
18. Simon J. Graham
19. Bradley J. MacIntosh

Reviewed by ScreenIT