Molecular Biology

  1. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

    1. Jessie Huang
    2. Adam J. Hume
    3. Kristine M. Abo
    4. Rhiannon B. Werder
    5. Carlos Villacorta-Martin
    6. Konstantinos-Dionysios Alysandratos
    7. Mary Lou Beermann
    8. Chantelle Simone-Roach
    9. Jonathan Lindstrom-Vautrin
    10. Judith Olejnik
    11. Ellen L. Suder
    12. Esther Bullitt
    13. Anne Hinds
    14. Arjun Sharma
    15. Markus Bosmann
    16. Ruobing Wang
    17. Finn Hawkins
    18. Eric J. Burks
    19. Mohsan Saeed
    20. Andrew A. Wilson
    21. Elke Mühlberger
    22. Darrell N. Kotton

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  2. Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2

    1. Youngchang Kim
    2. Jacek Wower
    3. Natalia Maltseva
    4. Changsoo Chang
    5. Robert Jedrzejczak
    6. Mateusz Wilamowski
    7. Soowon Kang
    8. Vlad Nicolaescu
    9. Glenn Randall
    10. Karolina Michalska
    11. Andrzej Joachimiak

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  3. In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges

    1. Beata Turoňová
    2. Mateusz Sikora
    3. Christoph Schürmann
    4. Wim J. H. Hagen
    5. Sonja Welsch
    6. Florian E. C. Blanc
    7. Sören von Bülow
    8. Michael Gecht
    9. Katrin Bagola
    10. Cindy Hörner
    11. Ger van Zandbergen
    12. Jonathan Landry
    13. Nayara Trevisan Doimo de Azevedo
    14. Shyamal Mosalaganti
    15. Andre Schwarz
    16. Roberto Covino
    17. Michael D. Mühlebach
    18. Gerhard Hummer
    19. Jacomine Krijnse Locker
    20. Martin Beck

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  4. Elucidation of the antiviral mechanism of cystine and theanine through transcriptome analysis of mice and comparison with COVID-19 gene set data

    1. Akira Mitsui
    2. Ryosei Sakai
    3. Kiyoshi Miwa
    4. Susumu Shibahara
    5. Shigekazu Kurihara
    6. Kenji Nagao

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  5. AGE IS ASSOCIATED WITH INCREASED EXPRESSION OF PATTERN RECOGNITION RECEPTOR GENES AND ACE2 , THE RECEPTOR FOR SARS-COV-2: IMPLICATIONS FOR THE EPIDEMIOLOGY OF COVID-19 DISEASE

    1. Stephen W. Bickler
    2. David M. Cauvi
    3. Kathleen M. Fisch
    4. James M. Prieto
    5. Alicia D. Gaidry
    6. Hariharan Thangarajah
    7. David Lazar
    8. Romeo Ignacio
    9. Dale R. Gerstmann
    10. Allen F. Ryan
    11. Philip E. Bickler
    12. Antonio De Maio

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  6. Calreticulin co-expression supports high level production of a recombinant SARS-CoV-2 spike mimetic in Nicotiana benthamiana

    1. Emmanuel Margolin
    2. Matthew Verbeek
    3. Ann Meyers
    4. Ros Chapman
    5. Anna-Lise Williamson
    6. Edward P Rybicki

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  7. Dynamics of the ACE2 - SARS-CoV/SARS-CoV-2 spike protein interface reveal unique mechanisms

    1. Amanat Ali
    2. Ranjit Vijayan

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  8. Chimeric synthetic reference standards enable cross-validation of positive and negative controls in SARS-CoV-2 molecular tests

    1. Bindu Swapna Madala
    2. Andre L. M. Reis
    3. Ira W. Deveson
    4. William Rawlinson
    5. Tim R. Mercer

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  9. An Inexpensive RT-PCR Endpoint Diagnostic Assay for SARS-CoV-2 Using Nested PCR: Direct Assessment of Detection Efficiency of RT-qPCR Tests and Suitability for Surveillance

    1. Jayeshkumar Narsibhai Davda
    2. Keith Frank
    3. Sivakumar Prakash
    4. Gunjan Purohit
    5. Devi Prasad Vijayashankar
    6. Dhiviya Vedagiri
    7. Karthik Bharadwaj Tallapaka
    8. Krishnan Harinivas Harshan
    9. Archana Bharadwaj Siva
    10. Rakesh Kumar Mishra
    11. Jyotsna Dhawan
    12. Imran Siddiqi

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  10. Effects of Renin-Angiotensin Inhibition on ACE2 and TMPRSS2 Expression: Insights into COVID-19

    1. Congqing Wu
    2. Dien Ye
    3. Adam E. Mullick
    4. Zhenyu Li
    5. A.H. Jan Danser
    6. Alan Daugherty
    7. Hong S. Lu

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