Microbiology

  1. Z-RNA and the flipside of the SARS Nsp13 helicase

    1. Alan Herbert
    2. Maria Poptsova

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Comparative infection and pathogenesis of SARS-CoV-2 Omicron and Delta variants in aged and young Syrian hamsters

    1. Nadia Storm
    2. Nicholas A. Crossland
    3. Lindsay G. A. McKay
    4. Anthony Griffiths

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. A structural dynamic explanation for observed escape of SARS-CoV-2 BA.2 variant mutation S371L/F

    1. Nathaniel L. Miller
    2. Thomas Clark
    3. Rahul Raman
    4. Ram Sasisekharan

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

    1. Philip W Fowler
    2. Carla Wright
    3. Helen Spiers
    4. Tingting Zhu
    5. Elisabeth ML Baeten
    6. Sarah W Hoosdally
    7. Ana L Gibertoni Cruz
    8. Aysha Roohi
    9. Samaneh Kouchaki
    10. Timothy M Walker
    11. Timothy EA Peto
    12. Grant Miller
    13. Chris Lintott
    14. David Clifton
    15. Derrick W Crook
    16. A Sarah Walker
    17. The Zooniverse Volunteer Community
    18. The CRyPTIC Consortium

    • Curated by eLife

      Evaluation Summary:

      The authors evaluate a novel crowd-sourcing method to interpret minimum inhibitory concentrations of Mycobacterium tuberculosis, the causative agent of tuberculosis. To provide valuable test results without the need for available expert mycobacteriologists, the authors demonstrate that when presented appropriately, 11-17 interpretations by lay interpreters can provide reproducible results for most tuberculosis drugs. This analysis demonstrates that among those samples that can be reliably interpreted by automated detection software, lay interpretation provides a potential alternative means to provide a timely confirmatory read. The work will be of interest to bacteriologists and those with an interest in antimicrobial resistance.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  5. Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infection during SARS-CoV-2 Infection

    1. Amanda P. Smith
    2. Evan P. Williams
    3. Taylor R. Plunkett
    4. Muneeswaran Selvaraj
    5. Lindey C. Lane
    6. Lillian Zalduondo
    7. Yi Xue
    8. Peter Vogel
    9. Rudragouda Channappanavar
    10. Colleen B. Jonsson
    11. Amber M. Smith

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2

    1. Farhad Vesuna
    2. Ivan Akhrymuk
    3. Amy Smith
    4. Paul T. Winnard
    5. Shih-Chao Lin
    6. Lauren Panny
    7. Robert Scharpf
    8. Kylene Kehn-Hall
    9. Venu Raman

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

    1. Yi Wu
    2. Yanqiong Shen
    3. Namei Wu
    4. Xinghai Zhang
    5. Shaohong Chen
    6. Chang Yang
    7. Junhui Zhou
    8. Yan Wu
    9. Da Chen
    10. Li Wang
    11. Chao Wang
    12. Huajun Zhang
    13. Ninuo Xia
    14. Sandra Chiu
    15. Yucai Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission

    1. Bradley Pickering
    2. Oliver Lung
    3. Finlay Maguire
    4. Peter Kruczkiewicz
    5. Jonathon D. Kotwa
    6. Tore Buchanan
    7. Marianne Gagnier
    8. Jennifer L. Guthrie
    9. Claire M. Jardine
    10. Alex Marchand-Austin
    11. Ariane Massé
    12. Heather McClinchey
    13. Kuganya Nirmalarajah
    14. Patryk Aftanas
    15. Juliette Blais-Savoie
    16. Hsien-Yao Chee
    17. Emily Chien
    18. Winfield Yim
    19. Andra Banete
    20. Bryan D. Griffin
    21. Lily Yip
    22. Melissa Goolia
    23. Matthew Suderman
    24. Mathieu Pinette
    25. Greg Smith
    26. Daniel Sullivan
    27. Josip Rudar
    28. Oksana Vernygora
    29. Elizabeth Adey
    30. Michelle Nebroski
    31. Guillaume Goyette
    32. Andrés Finzi
    33. Geneviève Laroche
    34. Ardeshir Ariana
    35. Brett Vahkal
    36. Marceline Côté
    37. Allison J. McGeer
    38. Larissa Nituch
    39. Samira Mubareka
    40. Jeff Bowman

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Discovery of a Novel Coronavirus in Swedish Bank Voles (Myodes glareolus)

    1. Anishia Wasberg
    2. Jayna Raghwani
    3. Jinlin Li
    4. John H.-O. Pettersson
    5. Johanna F. Lindahl
    6. Åke Lundkvist
    7. Jiaxin Ling

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Adenosine A2A Receptor (A 2A R) agonists improve survival in K28-hACE2 mice following SARS CoV-2 infection

    1. Barbara J. Mann
    2. Preeti Chhabra
    3. Mingyang Ma
    4. Savannah G. Brovero
    5. Marieke K. Jones
    6. Joel Linden
    7. Kenneth L. Brayman

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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