Microbiology

Soil protists can actively redistribute beneficial bacteria along Medicago truncatula roots

1. Christopher J. Hawxhurst
2. Jamie L. Micciulla
3. Charles M. Bridges
4. Mikhael Shor
5. Daniel J. Gage
6. Leslie M. Shor

Reviewed by Arcadia Science

Guild and Niche Determination Enable Targeted Alteration of the Microbiome

1. Oriane Moyne
2. Mahmoud Al-Bassam
3. Chloe Lieng
4. Deepan Thiruppathy
5. Grant J. Norton
6. Manish Kumar
7. Eli Haddad
8. Livia S. Zaramela
9. Karsten Zengler

Reviewed by Arcadia Science

Bacterial cGAS-like enzymes produce 2′,3′-cGAMP to activate an ion channel that restricts phage replication

1. Uday Tak
2. Peace Walth
3. Aaron T. Whiteley

Reviewed by Arcadia Science

A pH-sensitive switch activates virulence in Salmonella

1. Dasvit Shetty
2. Linda J Kenney

• Curated by eLife

  eLife assessment

  Salmonella invades and survives in host cells via SPI-1 and SPI-2 type III secretion system mechanisms, with the SPI-2 system allowing for intracellular survival in Salmonella-containing vacuoles, which have a low-pH environment. Transcription of SPI-2 genes at low pH is activated by the DNA-binding SsrB protein, which sits at the top of the SPI-2 regulatory hierarchy. This study provides important insights as to how SsrB is allosterically affected by pH resulting in acid-dependent DNA binding. However, there are concerns about some experiments, and the evidence presented is not fully conclusive.

Reviewed by eLife

ORBIT for E. coli : Kilobase-scale oligonucleotide recombineering at high throughput and high efficiency

1. Scott H. Saunders
2. Ayesha M. Ahmed

Reviewed by Arcadia Science

Novel role for peptidoglycan carboxypeptidases in maintaining the balance between bacterial cell wall synthesis and degradation

1. Manuela Alvarado Obando
2. Tobias Dörr

Reviewed by Arcadia Science

Replaying the tape of ecology to domesticate wild microbiota

1. Alberto Pascual-García
2. Damian Rivett
3. Matt L. Jones
4. Thomas Bell

Reviewed by Arcadia Science

Decomposing a San Francisco estuary microbiome using long-read metagenomics reveals species- and strain-level dominance from picoeukaryotes to viruses

1. Lauren M. Lui
2. Torben N. Nielsen

Reviewed by Arcadia Science

A Highly Immunogenic Measles Virus-based Th1-biased COVID-19 Vaccine

1. Cindy Hörner
2. Christoph Schürmann
3. Arne Auste
4. Aileen Ebenig
5. Samada Muraleedharan
6. Maike Herrmann
7. Barbara Schnierle
8. Michael D. Mühlebach

Reviewed by ScreenIT

Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

1. Joseph W. Golden
2. Curtis R. Cline
3. Xiankun Zeng
4. Aura R. Garrison
5. Brian D. Carey
6. Eric M. Mucker
7. Lauren E. White
8. Joshua D. Shamblin
9. Rebecca L. Brocato
10. Jun Liu
11. April M. Babka
12. Hypaitia B. Rauch
13. Jeffrey M. Smith
14. Bradley S. Hollidge
15. Collin Fitzpatrick
16. Catherine V. Badger
17. Jay W. Hooper

Reviewed by ScreenIT