Microbiology

Water-soluble tocopherol derivatives inhibit SARS-CoV-2 RNA-dependent RNA polymerase

1. Hayden T. Pacl
2. Jennifer L. Tipper
3. Ritesh R. Sevalkar
4. Andrew Crouse
5. Camerron Crowder
6. UAB Precision Medicine Institute
7. Shama Ahmad
8. Aftab Ahmad
9. Gillian D. Holder
10. Charles J. Kuhlman
11. Krishna C. Chinta
12. Sajid Nadeem
13. Todd J. Green
14. Chad M. Petit
15. Adrie J.C. Steyn
16. Matthew Might
17. Kevin S. Harrod

Reviewed by ScreenIT

hnRNPA1 regulates early translation to replication switch in SARS-CoV-2 life cycle

1. Ram Kumar
2. Yogesh Chander
3. Nitin Khandelwal
4. Himanshu Nagori
5. Assim Verma
6. Yash Pal
7. Baldev R. Gulati
8. Bhupendra N. Tripathi
9. Sanjay Barua
10. Naveen Kumar

Reviewed by ScreenIT

Improving human coronavirus OC43 (HCoV-OC43) research comparability in studies using HCoV-OC43 as a surrogate for SARS-CoV-2

1. Erin E. Schirtzinger
2. Yunjeong Kim
3. A. Sally Davis

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A Drug Candidate for Treating Adverse Reactions Caused by Pathogenic Antibodies Inducible by SARS-CoV-2 Virus and Vaccines

1. Huiru Wang
2. Xiancong Wu
3. Lin Dai
4. Yue Hu
5. Yuekai Zhang
6. Yuxing Chen
7. Xiaoling Liu

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Niclosamide reverses SARS-CoV-2 control of lipophagy

1. Timothy J. Garrett
2. Heather Coatsworth
3. Iqbal Mahmud
4. Timothy Hamerly
5. Caroline J. Stephenson
6. Hoda S. Yazd
7. Jasmine Ayers
8. Megan R. Miller
9. John A. Lednicky
10. Rhoel R. Dinglasan

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Pathogenic and transcriptomic differences of emerging SARS-CoV-2 variants in the Syrian golden hamster model

1. Kyle L. O'Donnell
2. Amanda N. Pinski
3. Chad S. Clancy
4. Tylisha Gourdine
5. Kyle Shifflett
6. Paige Fletcher
7. Ilhem Messaoudi
8. Andrea Marzi

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A mouse-adapted SARS-CoV-2 strain replicating in standard laboratory mice

1. Xavier Montagutelli
2. Matthieu Prot
3. Grégory Jouvion
4. Laurine Levillayer
5. Laurine Conquet
6. Edouard Reyes-Gomez
7. Flora Donati
8. Melanie Albert
9. Sylvie van der Werf
10. Jean Jaubert
11. Etienne Simon-Lorière

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Host Cellular RNA Helicases Regulate SARS-CoV-2 Infection

1. Yasuo Ariumi

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Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression

1. Isao Masuda
2. Jae-Yeon Hwang
3. Thomas Christian
4. Sunita Maharjan
5. Fuad Mohammad
6. Howard Gamper
7. Allen R Buskirk
8. Ya-Ming Hou

• Curated by eLife

  Evaluation Summary:

  This manuscript provides evidence that loss of N1-methylation of G37 of tRNAs in bacteria on depletion of TrmD results in defects in aminoacylation and peptidyl-transfer, leading to ribosome stalling and phenotypes indicating activation of the stringent response.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Therapeutic efficacy of CT-P59 against P.1 variant of SARS-CoV-2

1. Dong-Kyun Ryu
2. Bobin Kang
3. Sun-Je Woo
4. Min-Ho Lee
5. Aloys SL Tijsma
6. Hanmi Noh
7. Jong-In Kim
8. Ji-Min Seo
9. Cheolmin Kim
10. Minsoo Kim
11. Eunji Yang
12. Gippeum Lim
13. Seong-Gyu Kim
14. Su-Kyeong Eo
15. Jung-ah Choi
16. Sang-Seok Oh
17. Patricia M Nuijten
18. Manki Song
19. Hyo-Young Chung
20. Carel A van Baalen
21. Ki-Sung Kwon
22. Soo-Young Lee

Reviewed by ScreenIT