Microbiology

  1. Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

    1. Yaozong Chen
    2. Lulu Sun
    3. Irfan Ullah
    4. Guillaume Beaudoin-Bussières
    5. Sai Priya Anand
    6. Andrew P. Hederman
    7. William D. Tolbert
    8. Rebekah Sherburn
    9. Dung N. Nguyen
    10. Lorie Marchitto
    11. Shilei Ding
    12. Di Wu
    13. Yuhong Luo
    14. Suneetha Gottumukkala
    15. Sean Moran
    16. Priti Kumar
    17. Grzegorz Piszczek
    18. Walther Mothes
    19. Margaret E. Ackerman
    20. Andrés Finzi
    21. Pradeep D. Uchil
    22. Frank J. Gonzalez
    23. Marzena Pazgier

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. RNase III-mediated processing of a trans-acting bacterial sRNA and its cis-encoded antagonist

    1. Sarah Lauren Svensson
    2. Cynthia Mira Sharma

    • Curated by eLife

      Evaluation Summary:

      Campylobacter jejuni is serious food-borne pathogen and understanding how the various products necessary for pathogenesis are regulated is a key step in preventing its growth and/or treating disease. Here, Sharma and coworkers describe the complex pathway that leads to the maturation of two complementary regulatory RNAs and how one of the RNAs antagonizes the other to relieve repression of a virulence-related gene.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the reviewers.)

    Reviewed by eLife

    9 evaluationsAppears in 1 listLatest version Latest activity

  3. Antiviral activity of Molnupiravir precursor NHC against SARS-CoV-2 Variants of Concern (VOCs) and implications for the therapeutic window and resistance

    1. Tessa Prince
    2. I’ah Donovan-Banfield
    3. Hannah Goldswain
    4. Rebekah Penrice-Randal
    5. Catherine Hartley
    6. Saye Khoo
    7. Tom Fletcher
    8. Julian A. Hiscox

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. SARS-CoV-2 spike protein as a bacterial lipopolysaccharide delivery system in an overzealous inflammatory cascade

    1. Firdaus Samsudin
    2. Palur Raghuvamsi
    3. Ganna Petruk
    4. Manoj Puthia
    5. Jitka Petrlova
    6. Paul MacAry
    7. Ganesh S Anand
    8. Peter J Bond
    9. Artur Schmidtchen

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

    4 evaluationsAppears in 3 listsLatest version Latest activity

  5. Glycan Masking of Epitopes in the NTD and RBD of the Spike Protein Elicits Broadly Neutralizing Antibodies Against SARS-CoV-2 Variants

    1. Wei-Shuo Lin
    2. I-Chen Chen
    3. Hui-Chen Chen
    4. Yi-Chien Lee
    5. Suh-Chin Wu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Inactivation of SARS-CoV-2 and COVID-19 Patient Samples for Contemporary Immunology and Metabolomics Studies

    1. Devon J Eddins
    2. Leda C Bassit
    3. Joshua D Chandler
    4. Natalie S Haddad
    5. Kathryn L Musall
    6. Junkai Yang
    7. Astrid Kosters
    8. Brian S Dobosh
    9. Mindy R Hernández
    10. Richard P Ramonell
    11. Rabindra M Tirouvanziam
    12. F Eun-Hyung Lee
    13. Keivan Zandi
    14. Raymond F Schinazi
    15. Eliver E B Ghosn

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice

    1. Gema M. Olivarria
    2. Yuting Cheng
    3. Susana Furman
    4. Collin Pachow
    5. Lindsay A. Hohsfield
    6. Charlene Smith-Geater
    7. Ricardo Miramontes
    8. Jie Wu
    9. Mara S. Burns
    10. Kate I. Tsourmas
    11. Jennifer Stocksdale
    12. Cynthia Manlapaz
    13. William H. Yong
    14. John Teijaro
    15. Robert Edwards
    16. Kim N. Green
    17. Leslie M. Thompson
    18. Thomas E. Lane

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. A biosafety level 2 surrogate for studying SARS-CoV-2 survival in food processing environmental biofilms

    1. Austin B. Featherstone
    2. Sapna Chitlapilly Dass

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Activity

    1. Sabari Nath Neerukonda
    2. Russell Vassell
    3. Sabrina Lusvarghi
    4. Richard Wang
    5. Fernando Echegaray
    6. Lisa Bentley
    7. Ann E. Eakin
    8. Karl J. Erlandson
    9. Leah C. Katzelnick
    10. Carol D. Weiss
    11. Wei Wang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Susceptibility of sheep to experimental co-infection with the ancestral lineage of SARS-CoV-2 and its alpha variant

    1. Natasha N. Gaudreault
    2. Konner Cool
    3. Jessie D. Trujillo
    4. Igor Morozov
    5. David A. Meekins
    6. Chester McDowell
    7. Dashzeveg Bold
    8. Mariano Carossino
    9. Velmurugan Balaraman
    10. Dana Mitzel
    11. Taeyong Kwon
    12. Daniel W. Madden
    13. Bianca Libanori Artiaga
    14. Roman M. Pogranichniy
    15. Gleyder Roman-Sosa
    16. William C. Wilson
    17. Udeni B. R. Balasuriya
    18. Adolfo García-Sastre
    19. Juergen A. Richt

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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