Infectious Diseases (except HIV/AIDS)

Detection of Salmonella Typhi and bla _CTX-M Genes in Drinking Water, Wastewater, and Environmental Biofilms in Sindh Province, Pakistan

1. Ayesha Tajammul
2. L. Scott Benson
3. Jamil Ahmed
4. James VanDerslice
5. Windy Tanner

Reviewed by Rapid Reviews Infectious Diseases

A label-free optical biosensor-based point-of-care test for the rapid detection of Monkeypox virus

1. Mete Aslan
2. Elif Seymour
3. Howard Brickner
4. Alex E. Clark
5. Iris Celebi
6. Michael B. Townsend
7. Panayampalli S. Satheshkumar
8. Megan Riley
9. Aaron F. Carlin
10. M. Selim Ünlü
11. Partha Ray

Reviewed by Rapid Reviews Infectious Diseases

Leveraging mobility data to analyze persistent SARS-CoV-2 mutations and inform targeted genomic surveillance

1. Riccardo Spott
2. Mathias W Pletz
3. Carolin Fleischmann-Struzek
4. Aurelia Kimmig
5. Christiane Hadlich
6. Matthias Hauert
7. Mara Lohde
8. Mateusz Jundzill
9. Mike Marquet
10. Petra Dickmann
11. Ruben Schüchner
12. Martin Hölzer
13. Denise Kühnert
14. Christian Brandt

• Curated by eLife

  eLife Assessment

  The authors analyze the relationship between human mobility and genomic data of SARS-CoV-2 using mobile phone mobility data and sequence data and present a solid proof of concept. This useful work was conducted on a fine spatial scale and provides suggestions on how mobility-derived surveillance could be conducted, although these results are mixed. The primary significance of this work is the strong use of large datasets that were highly granular. The authors provide a rigorous study, but with less clear predictive power of mobility to inform transmission patterns.

Reviewed by eLife

Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children

1. Hamtandi M Natama
2. Jo Salkeld
3. Athanase Somé
4. Seyi Soremekun
5. Salou Diallo
6. Ousmane Traoré
7. Toussaint Rouamba
8. Florence Ouédraogo
9. Edouard Ouédraogo
10. K Carine Sonia Daboné
11. Nadine A Koné
12. Z Michael John Compaoré
13. Miguel Kafando
14. Massa dit Achille Bonko
15. Fabé Konaté
16. Hermann Sorgho
17. Carolyn M Nielsen
18. Dimitra Pipini
19. Ababacar Diouf
20. Lloyd D W King
21. Umesh Shaligram
22. Carole A Long
23. Jee-Sun Cho
24. Alison M Lawrie
25. Katherine Skinner
26. Rachel Roberts
27. Kazutoyo Miura
28. John Bradley
29. Sarah E Silk
30. Simon J Draper
31. Halidou Tinto
32. Angela M Minassian

Reviewed by PREreview

Fluorescent Antibody-Based Detection and Ultrastructural Analysis of Streptococcus pneumoniae in Human Sputum

1. Ana G. Jop Vidal
2. Meg Francis
3. Maneesha Chitanvis
4. Ithiel J. Frame
5. Poonam Sharma
6. Patricio Vidal
7. Claudio F. Lanata
8. Carlos Grijalva
9. William Daley
10. Jorge E. Vidal

Reviewed by PREreview

Toxoplasma Infection and Its Sequential Impact on Physical Health, Stress, and Anxiety: A Large Cross-Sectional Study Testing the Stress-Coping Hypothesis

1. Jaroslav Flegr
2. Ashkan Latifi
3. Šárka Kaňková

Reviewed by PREreview

Association of COVID-19 risk factors with systemic fungal infections in hospitalized patients

1. Abbygail C Wilbourn
2. Oleg V Tsodikov
3. Sylvie Garneau-Tsodikova

Reviewed by PREreview

The landscape of paediatric infectious disease exposure in a rural sub-Saharan Africa setting in Kilifi, Kenya: longitudinal serological analysis over two decades and priorities for future vaccine development

1. Deirdre F Foley
2. Timothy K Chege
3. Joyce Kabagenyi
4. Karen McCarthy
5. Elijah T Gicheru
6. Nelson Kibinge
7. Angela W Maina
8. Jacqueline M Waeni
9. Ralf Clemens
10. Sue-Ann Costa Clemens
11. James Tuju
12. Charles J Sande

Reviewed by PREreview

The effect of combining antibiotics on resistance: A systematic review and meta-analysis

1. Berit Siedentop
2. Viacheslav N Kachalov
3. Christopher Witzany
4. Matthias Egger
5. Roger D Kouyos
6. Sebastian Bonhoeffer

• Curated by eLife

  eLife assessment

  This is a methodologically state-of-the-art systematic review and meta-analysis of studies that addressed the question of whether the administration of multiple antibiotics simultaneously prevents antibiotic resistance development in individuals. The findings are solid. Rather than providing a precise answer, the synthesis of studies eligible for analysis leads to the conclusion that "our analysis could not identify any benefit or harm of using a higher or a lower number of antibiotics regarding within-patient resistance development." This article is important as it articulates the existing knowledge gap, but also serves as an example for careful future use of the meta-analysis methodology, when existing data just don't allow conclusions.

Reviewed by eLife

Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID

1. Patrick KA Kearns
2. Charles Dixon
3. Mihaly Badonyi
4. Kim Lee
5. Rafal Czapiewski
6. Olivia Fleming
7. Prajitha Nadukkandy
8. Lukas Gerasimivicius
9. Rinal Sahputra
10. Bethany Potts
11. Sam Benton
12. Jacky Guy
13. Scott Neilson
14. Helen Wise
15. Sara Jenks
16. Kate Templeton
17. CIRCO
18. Christina Dold
19. Teresa Lambe
20. Andrew Pollard
21. Alexander J Mentzer
22. Julian C Knight
23. COMBAT
24. Susanna Dunachie
25. Paul Klenerman
26. Eleanor Barnes
27. Alan Carson
28. Laura McWhirter
29. Tracy Hussell
30. Rennos Fragkoudis
31. Susan Rosser
32. David Cavanagh
33. Graeme Cowan
34. Madhvi Menon
35. Joseph A Marsh
36. Dirk A Kleinjan
37. Nick Gilbert

• Curated by eLife

  eLife assessment

  This study provides novel insights into COVID-19 immune responses by using the delta of the normalised accessible surface area (DASA) to map IgM responses to the SARS-CoV-2 Membrane protein M1-subtype across multiple European cohorts. The evidence supporting the findings is solid, with thorough validation and comprehensive analysis, although additional clarity on T-independent B cell reactions and the impact of comorbidities would further strengthen the conclusions. The methods and data presented are valuable for advancing diagnostic and prognostic tools for COVID-19, particularly in the context of long COVID.

Reviewed by eLife