Immunology

  1. A recombinant receptor-binding domain in trimeric form generates protective immunity against SARS-CoV-2 infection in nonhuman primates

    1. Limin Yang
    2. Deyu Tian
    3. Jian-bao Han
    4. Wenhui Fan
    5. Yuan Zhang
    6. Yunlong Li
    7. Wenqiang Sun
    8. Yanqiu Wei
    9. Xiaodong Tian
    10. Dan-dan Yu
    11. Xiao-li Feng
    12. Gong Cheng
    13. Yuhai Bi
    14. Yong-tang Zheng
    15. Wenjun Liu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Neutralisation of circulating SARS-CoV-2 delta and omicron variants by convalescent plasma and SARS-CoV-2 hyperimmune intravenous human immunoglobulins for treatment of COVID-19

    1. Fatema Tuz Zahra
    2. Lorenza Bellusci
    3. Gabrielle Grubbs
    4. Hana Golding
    5. Surender Khurana

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Rationally designed immunogens enable immune focusing to the SARS-CoV-2 receptor binding motif

    1. Blake M. Hauser
    2. Maya Sangesland
    3. Kerri J. St. Denis
    4. Ian W. Windsor
    5. Jared Feldman
    6. Evan C. Lam
    7. Ty Kannegieter
    8. Alejandro B. Balazs
    9. Daniel Lingwood
    10. Aaron G. Schmidt

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

    1. Nikhil Faulkner
    2. Kevin W Ng
    3. Mary Y Wu
    4. Ruth Harvey
    5. Marios Margaritis
    6. Stavroula Paraskevopoulou
    7. Catherine Houlihan
    8. Saira Hussain
    9. Maria Greco
    10. William Bolland
    11. Scott Warchal
    12. Judith Heaney
    13. Hannah Rickman
    14. Moria Spyer
    15. Daniel Frampton
    16. Matthew Byott
    17. Tulio de Oliveira
    18. Alex Sigal
    19. Svend Kjaer
    20. Charles Swanton
    21. Sonia Gandhi
    22. Rupert Beale
    23. Steve J Gamblin
    24. John W McCauley
    25. Rodney Stuart Daniels
    26. Michael Howell
    27. David Bauer
    28. Eleni Nastouli
    29. George Kassiotis

    • Curated by eLife

      Evaluation Summary:

      This study describes reduced antibody cross-reactivity between the SARS-CoV-2 B.1.1.7 variant and the parental strain or the B.1.351 variant. Asymmetric antibody responses and reduced neutralizing antibodies against heterogeneous variants have been demonstrated in multiple studies. The current study reports reduction of B.1.1.7 COVID-19 sera against the SARS-CoV-2 parental strain and B.1.351. This observation is interesting and could be useful for future vaccine development. The work is of interest to virologists and infectious disease specialists.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife, ScreenIT

    5 evaluationsAppears in 2 listsLatest version Latest activity

  5. Decreased neutralization of SARS-CoV-2 global variants by therapeutic anti-spike protein monoclonal antibodies

    1. Takuya Tada
    2. Belinda M. Dcosta
    3. Hao Zhou
    4. Ada Vaill
    5. Wes Kazmierski
    6. Nathaniel R. Landau

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Isolation and Characterization of Cross-Neutralizing Coronavirus Antibodies from COVID-19+ Subjects

    1. Madeleine F. Jennewein
    2. Anna J. MacCamy
    3. Nicholas R. Akins
    4. Junli Feng
    5. Leah J. Homad
    6. Nicholas K. Hurlburt
    7. Emily Seydoux
    8. Yu-Hsin Wan
    9. Andrew B. Stuart
    10. Venkata Viswanadh Edara
    11. Katharine Floyd
    12. Abigail Vanderheiden
    13. John R. Mascola
    14. Nicole Doria-Rose
    15. Lingshu Wang
    16. Eun Sung Yang
    17. Helen Y. Chu
    18. Jonathan L. Torres
    19. Gabriel Ozorowski
    20. Andrew B. Ward
    21. Rachael E. Whaley
    22. Kristen W. Cohen
    23. Marie Pancera
    24. M. Juliana McElrath
    25. Janet A. Englund
    26. Andrés Finzi
    27. Mehul S. Suthar
    28. Andrew T. McGuire
    29. Leonidas Stamatatos

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Development of Equine Immunoglobulin Fragment F(ab’) 2 with High Neutralizing Capability against SARS-CoV-2

    1. Divya Gupta
    2. Farhan Ahmed
    3. Dixit Tandel
    4. Haripriya Parthasarathy
    5. Dhiviya Vedagiri
    6. Vishal Sah
    7. B Krishna Mohan
    8. Siddarth Daga
    9. Rafiq Ahmad Khan
    10. Chiranjeevi Kondiparthi
    11. Prabhudas Savari
    12. Sandesh Jain
    13. Jaya Daga
    14. Shashikala Reddy
    15. Nooruddin Khan
    16. Krishnan Harinivas Harshan

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Interactions of SARS-CoV-2 infection with chronic obesity inflammation: a complex network phenomenon

    1. Giovani Marino Favero
    2. Luis Paulo Gomes Mascarenhas
    3. Meirielly Furmann
    4. Juliana Berton
    5. Pedro Jeferson Miranda

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Distinct SARS-CoV-2 Antibody Responses Elicited by Natural Infection and mRNA Vaccination

    1. Rafael Assis
    2. Aarti Jain
    3. Rie Nakajima
    4. Al Jasinskas
    5. Saahir Kahn
    6. Anton Palma
    7. Daniel M. Parker
    8. Anthony Chau
    9. Amanda Leung
    10. Christina Grabar
    11. Fjolla Muqolli
    12. Ghali Khalil
    13. Jessica Colin Escobar
    14. Jenny Ventura
    15. D. Huw Davies
    16. Bruce Albala
    17. Bernadette Boden-Albala
    18. Sebastian Schubl
    19. Philip L. Felgner

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. GABA administration limits viral replication and pneumonitis in a mouse model of COVID-19

    1. Jide Tian
    2. Blake Middleton
    3. Daniel L. Kaufman

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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