Immunology

  1. An Orally Available Cathepsin L Inhibitor Protects Lungs Against SARS-CoV-2-Induced Diffuse Alveolar Damage in African Green Monkeys

    1. Felix W. Frueh
    2. Daniel C. Maneval
    3. Rudolf P. Bohm
    4. Jason P. Dufour
    5. Robert V. Blair
    6. Kathy Powell
    7. Pyone P. Aye
    8. Nadia A. Golden
    9. Chad J Roy
    10. Sky Spencer
    11. Kasi Russsell-Lodrigue
    12. Kenneth S. Plante
    13. Jessica A. Plante
    14. James McKerrow
    15. Jay Rappaport

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. Previously unrecognized non-reproducible antibody-antigen interactions and their implications for diagnosis of viral infections including COVID-19

    1. Jiaojiao Pan
    2. Lan Yang
    3. Yi Deng
    4. Baoqing Sun
    5. Li Zhang
    6. Wenya Wu
    7. Jingzhi Li
    8. Hu Cheng
    9. Yiting Li
    10. Wenwen Xu
    11. Jiao Yang
    12. Yiyue Sun
    13. Hao Fei
    14. Qinghong Xue
    15. Youxin Zhou
    16. Hui Wang
    17. Peiyan Zheng
    18. Hao Chen
    19. Fengcai Zhu
    20. Daxin Peng
    21. Dayong Gu
    22. Jun Han
    23. Jiwan Qiu
    24. Hongwei Ma

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Immunogenic SARS-CoV2 Epitopes Defined by Mass Spectrometry

    1. Ke Pan
    2. Yulun Chiu
    3. Eric Huang
    4. Michelle Chen
    5. Junmei Wang
    6. Ivy Lai
    7. Shailbala Singh
    8. Rebecca Shaw
    9. Michael MacCoss
    10. Cassian Yee

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

    1. Sam Afkhami
    2. Michael R. D’Agostino
    3. Ali Zhang
    4. Hannah D. Stacey
    5. Art Marzok
    6. Alisha Kang
    7. Ramandeep Singh
    8. Jegarubee Bavananthasivam
    9. Gluke Ye
    10. Xiangqian Luo
    11. Fuan Wang
    12. Jann C. Ang
    13. Anna Zganiacz
    14. Uma Sankar
    15. Natallia Kazhdan
    16. Joshua F.E. Koenig
    17. Allyssa Phelps
    18. Steven F. Gameiro
    19. Shangguo Tang
    20. Manel Jordana
    21. Yonghong Wan
    22. Karen L. Mossman
    23. Mangalakumari Jeyanathan
    24. Amy Gillgrass
    25. Maria Fe C. Medina
    26. Fiona Smaill
    27. Brian D. Lichty
    28. Matthew S. Miller
    29. Zhou Xing

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2

    1. Mariana F. Tioni
    2. Robert Jordan
    3. Angie Silva Pena
    4. Aditya Garg
    5. Danlu Wu
    6. Shannon I. Phan
    7. Christopher M. Weiss
    8. Xing Cheng
    9. Jack Greenhouse
    10. Tatyana Orekov
    11. Daniel Valentin
    12. Swagata Kar
    13. Laurent Pessaint
    14. Hanne Andersen
    15. Christopher C. Stobart
    16. Melissa H. Bloodworth
    17. R. Stokes Peebles
    18. Yang Liu
    19. Xuping Xie
    20. Pei-Yong Shi
    21. Martin L. Moore
    22. Roderick S. Tang

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Neutralization of SARS-CoV-2 Variants by mRNA and Adenoviral Vector Vaccine-Elicited Antibodies

    1. Takuya Tada
    2. Hao Zhou
    3. Marie I. Samanovic
    4. Belinda M. Dcosta
    5. Amber Cornelius
    6. Ramin S. Herati
    7. Mark J. Mulligan
    8. Nathaniel R. Landau

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. A single de novo substitution in SARS-CoV-2 spike informs enhanced adherence to human ACE2

    1. Elena Erausquin
    2. Jacinto López-Sagaseta

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Neutralization of recombinant RBD-subunit vaccine ZF2001-elicited antisera to SARS-CoV-2 variants including Delta

    1. Xin Zhao
    2. Anqi Zheng
    3. Dedong Li
    4. Rong Zhang
    5. Huan Sun
    6. Qihui Wang
    7. George F. Gao
    8. Pengcheng Han
    9. Lianpan Dai

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling

    1. Anastasia O Smirnova
    2. Anna M Miroshnichenkova
    3. Yulia V Olshanskaya
    4. Michael A Maschan
    5. Yuri B Lebedev
    6. Dmitriy M Chudakov
    7. Ilgar Z Mamedov
    8. Alexander Komkov

    • Curated by eLife

      Evaluation Summary:

      This paper describes a newly developed, publicly available algorithm (iROAR) that was tested on pre-exisiting datasets and is of interest to T and B cell immunologists who perform repertoire analysis via multiplex PCR based techniques. iROAR utilises naturally occurring non-functional sequences to improve and partially correct the amplification bias inherent in multiplex PCR based sequencing technologies.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  10. A modular protein subunit vaccine candidate produced in yeast confers protection against SARS-CoV-2 in non-human primates

    1. Neil C. Dalvie
    2. Lisa H. Tostanoski
    3. Sergio A Rodriguez-Aponte
    4. Kawaljit Kaur
    5. Sakshi Bajoria
    6. Ozan S. Kumru
    7. Amanda J. Martinot
    8. Abishek Chandrashekar
    9. Katherine McMahan
    10. Noe B. Mercado
    11. Jingyou Yu
    12. Aiquan Chang
    13. Victoria M. Giffin
    14. Felix Nampanya
    15. Shivani Patel
    16. Lesley Bowman
    17. Christopher A. Naranjo
    18. Dongsoo Yun
    19. Zach Flinchbaugh
    20. Laurent Pessaint
    21. Renita Brown
    22. Jason Velasco
    23. Elyse Teow
    24. Anthony Cook
    25. Hanne Andersen
    26. Mark G. Lewis
    27. Danielle L. Camp
    28. Judith Maxwell Silverman
    29. Harry Kleanthous
    30. Sangeeta B. Joshi
    31. David B. Volkin
    32. Sumi Biswas
    33. J. Christopher Love
    34. Dan H. Barouch

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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