Developmental Biology

  1. Site-specific DNA demethylation during spermatogenesis presets the sites of nucleosome retention in mouse sperm

    1. So Maezawa
    2. Masashi Yukawa
    3. Akihiko Sakashita
    4. Artem Barski
    5. Satoshi H Namekawa

    • Curated by eLife

      eLife Assessment

      This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that selective loss of DNA methylation at a subset of promoters is required for nucleosome retention and the establishment of epigenetic states that may influence embryonic gene regulation. The present study's conclusion is mostly supported by solid data.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  2. SRSF3 is a key regulator of epicardial formation

    1. Irina-Elena Lupu
    2. Susann Bruche
    3. Anob M. Chakrabarti
    4. Ian R. McCracken
    5. Tamara Carsana
    6. Andia N. Redpath
    7. Nicola Smart

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  3. Pleiotropic function of Dlx5/6 in coordinating the development of mammalian vocal and auditory organs

    1. Frida Sánchez-Garrido
    2. Victoria Bouzerand
    3. Markéta Kaiser
    4. Chloé Chaumeton
    5. Anastasia Fontaine
    6. Tomáš Zikmund
    7. Jozef Kaiser
    8. Églantine Heude

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  6. MMP21 behaves as a fluid flow transported morphogen to impart laterality during development

    1. Tim Ott
    2. Amelie Brugger
    3. Emmanuelle Szenker-Ravi
    4. Yvonne Kurrle
    5. Olivia Aberle
    6. Matthias Tisler
    7. Martin Blum
    8. Sandra Whalen
    9. Patrice Bouvagnet
    10. Bruno Reversade
    11. Axel Schweickert

    • Curated by eLife

      eLife Assessment

      This report explores the role of matrix metalloprotease MMP21 in left-right patterning in Xenopus. Based on a series of compelling experiments, the authors demonstrate that MMP21 can be secreted and acts upstream of dand5 without affecting cilia flow. The experiments are interesting and valuable; however, the claims by the authors lack consideration of other models that could also explain their findings.

    Reviewed by eLife

    2 evaluationsAppears in 1 listLatest version Latest activity

  8. Conserved Interhemispheric Morphogenesis in Amniotes Preceded the Evolution of the Corpus Callosum

    1. Ryota Noji
    2. Mari Kaneko
    3. Takaya Abe
    4. Hiroshi Kiyonari
    5. Yukihiro Nishikawa
    6. Takuma Kumamoto
    7. Hitoshi Gotoh
    8. Chiaki Ohtaka‐Maruyama
    9. Katsuhiko Ono
    10. Tatsuya Yoshizawa
    11. Tadashi Nomura

    Reviewed by Review Commons

    5 evaluationsAppears in 1 listLatest version Latest activity

  10. Identification of Specialized tRNA Expression in Early Human Brain Development

    1. Alex L. Bagi
    2. Todd M. Lowe
    3. Sofie R. Salama

    Reviewed by Life Science Editors Foundation

    1 evaluationAppears in 1 listLatest version Latest activity
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