Dermatology

Gasdermin D-Mediated Neutrophil Pyroptosis drives Inflammation in Psoriasis

1. Jian Liu
2. YuYing Jiang
3. ZiYue Diao
4. DanDan Chen
5. RuiYuan Xia
6. BingWei Wang
7. Shuo Yang
8. ZhiQiang Yin

• Curated by eLife

  eLife Assessment

  This is a potentially interesting study regarding the role of gasdesmin D in experimental psoriasis. The study contains useful data from murine models of skin inflammation, however the main claims (on neutrophil pyroptosis) are incompletely supported in its current form and require additional experimental support to justify the conclusions made.

Reviewed by eLife

Single-cell analysis of psoriasis resolution reveals an inflammatory fibroblast state targeted by IL-23 blockade

1. Luc Francis
2. Daniel McCluskey
3. Clarisse Ganier
4. Treasa Jiang
5. Xinyi Du-Harpur
6. Jeyrroy Gabriel
7. Pawan Dhami
8. Yogesh Kamra
9. Sudha Visvanathan
10. Jonathan N. Barker
11. Catherine H. Smith
12. Francesca Capon
13. Satveer K. Mahil

Reviewed by Arcadia Science

Timing of PCR and antibody testing in patients with COVID-19–associated dermatologic manifestations

1. Esther E. Freeman
2. Devon E. McMahon
3. George J. Hruza
4. Jules B. Lipoff
5. Lars E. French
6. Lindy P. Fox
7. Marlys S. Fassett

Reviewed by ScreenIT

COVID-19 and Herpes Simplex Virus Infection: A Cross-Sectional Study

1. Mohammed Shanshal
2. Hayder Saad Ahmed

Reviewed by ScreenIT

Describing the burden of the COVID‐19 pandemic in people with psoriasis: findings from a global cross‐sectional study

1. S.K. Mahil
2. M. Yates
3. Z.Z.N. Yiu
4. S.M. Langan
5. T. Tsakok
6. N. Dand
7. K.J. Mason
8. H. McAteer
9. F. Meynell
10. B. Coker
11. A. Vincent
12. D. Urmston
13. A. Vesty
14. J. Kelly
15. C. Lancelot
16. L. Moorhead
17. H. Bachelez
18. F. Capon
19. C.R. Contreras
20. C. De La Cruz
21. P. Di Meglio
22. P. Gisondi
23. D. Jullien
24. J. Lambert
25. L. Naldi
26. S. Norton
27. L. Puig
28. P. Spuls
29. T. Torres
30. R.B. Warren
31. H. Waweru
32. J. Weinman
33. M.A. Brown
34. J.B. Galloway
35. C.M. Griffiths
36. J.N. Barker
37. C.H. Smith
38. the PsoProtect study group

Reviewed by ScreenIT

Impact of COVID-19 on medical practice: A nationwide survey of dermatologists and health care providers in Iraq

1. Mohammed Shanshal
2. Hayder Saad Ahmed
3. Hayder Asfoor
4. Raad Ibrahim Salih
5. Shehab Ahmed Ali
6. Yusif K. Aldabouni

Reviewed by ScreenIT

The successful introduction of a hand dermatitis clinic to reduce occupational dermatoses during the covid-19 pandemic

1. Sarah Walsh
2. Siobhan Carey

Reviewed by ScreenIT

The spectrum of COVID-19–associated dermatologic manifestations: An international registry of 716 patients from 31 countries

1. Esther E. Freeman
2. Devon E. McMahon
3. Jules B. Lipoff
4. Misha Rosenbach
5. Carrie Kovarik
6. Seemal R. Desai
7. Joanna Harp
8. Junko Takeshita
9. Lars E. French
10. Henry W. Lim
11. Bruce H. Thiers
12. George J. Hruza
13. Lindy P. Fox

Reviewed by ScreenIT

Method development and characterisation of the low-molecular-weight peptidome of human wound fluids

1. Mariena JA van der Plas
2. Jun Cai
3. Jitka Petrlova
4. Karim Saleh
5. Sven Kjellström
6. Artur Schmidtchen

• Curated by eLife

  Evaluation Summary:

  This well-done study establishes a work flow for the analysis of the peptidome of wound fluids. By doing so it enables the identification of peptide patterns associated with wounds that are healing versus non-healing. The method may therefore help to define candidate biomarkers for wound healing. Overall enthusiasm was somewhat dampened by findings previously reported by the same group and also by others.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife