Cell Biology

Re-assessment of the subcellular localization of Bazooka/Par-3 in Drosophila : No evidence for localization to the nucleus and the neuromuscular junction

1. Soya Kim
2. Jaffer Shahab
3. Andreas Wodarz

Reviewed by Review Commons

ESCRT disruption provides evidence against signaling functions for synaptic exosomes

1. Erica C Dresselhaus
2. Kathryn P Harris
3. Cassandra R R Blanchette
4. Kate Koles
5. Steven J Del Signore
6. Matthew F Pescosolido
7. Biljana Ermanoska
8. Mark Rozencwaig
9. Rebecca C Soslowsky
10. Michael J Parisi
11. Bryan A Stewart
12. Timothy J Mosca
13. Avital Adah Rodal

Reviewed by Review Commons

Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation

1. Mohammad Zeeshan
2. Ravish Rashpa
3. David J. Ferguson
4. George Mckeown
5. Raushan Nugmanova
6. Amit K. Subudhi
7. Raphael Beyeler
8. Sarah L. Pashley
9. Robert Markus
10. Declan Brady
11. Magali Roques
12. Andrew R. Bottrill
13. Andrew M. Fry
14. Arnab Pain
15. Sue Vaughan
16. Anthony A. Holder
17. Eelco C. Tromer
18. Mathieu Brochet
19. Rita Tewari

Reviewed by Review Commons

Gαi2 Interaction with EB1 Controls Microtubule Dynamics and Rac1 Activity in Xenopus Neural Crest Cell Migration

1. Soraya Villaseca
2. Juan Ignacio Leal
3. Lina Mariana Tovar
4. María José Ruiz
5. Jossef Guajardo
6. Hernan Morales-Navarrete
7. Roberto Mayor
8. Marcela Torrejón

Reviewed by Review Commons

Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

1. Carola Maria Morell
2. Samantha Grace Tilson
3. Rute Alexandra Tomaz
4. Arash Shahsavari
5. Andi Munteanu
6. Giovanni Canu
7. Brandon Tyler Wesley
8. Marion Perrin
9. Imbisaat Geti
10. Subhankar Mukhopadhyay
11. Francesca Mazzacuva
12. Paul Gissen
13. Jose Garcia-Bernardo
14. Martin Bachman
15. Casey Allison Rimland
16. Fotios Sampaziotis
17. Irina Mohorianu
18. Ludovic Vallier

• Curated by eLife

  eLife assessment

  The authors present an important study of a multi-cellular platform involving co-culturing of various hiPSC-derived hepatocyte like cells, cholangiocytes, stellate cells and macrophages to mimic the liver microenvironment. The aggregates are then treated with fatty acids and examined through transcriptomic and functional assays. The techniques and methodologically are sound, and the evidence supporting the conclusion is convincing, although more clinically relevant data demonstrating the effect of some potential pharmacological agents on the platform would serve to strengthen the study.

Reviewed by eLife