Biophysics

Prediction of Ca ²⁺ Binding Site in Proteins With a Fast and Accurate Method Based on Statistical Mechanics and Analysis of Crystal Structures

1. Abdul Basit
2. Devapriya Choudhury
3. Pradipta Bandyopadhyay

Reviewed by PREreview

The French flag problem revisited: Creating robust and tunable axial patterns without global signaling

1. Stephan Kremser
2. Gabriel Vercelli
3. Ulrich Gerland

• Curated by eLife

  eLife assessment

  This important study uses cellular automata and evolution algorithms to offer an alternative to long-range signalling models of developmental patterning. The computational evidence that local rules suffice to produce a robust and global pattern is convincing. With some additional insights that connect the theoretical findings back to real biological examples, this work could be of interest to the broad community of developmental and systems biologists.

Reviewed by eLife

Metric Ion Classification (MIC): A deep learning tool for assigning ions and waters in cryo-EM and x-ray crystallography structures

1. Laura Shub
2. Wenjin Liu
3. Georgios Skiniotis
4. Michael J. Keiser
5. Michael J. Robertson

Reviewed by PREreview