Bioengineering

  1. LabOS: The AI-XR Co-Scientist That Sees and Works With Humans

    1. Le Cong
    2. David Smerkous
    3. Xiaotong Wang
    4. Di Yin
    5. Zaixi Zhang
    6. Ruofan Jin
    7. Yinkai Wang
    8. Michal Gerasimiuk
    9. Ravi K. Dinesh
    10. Alex Smerkous
    11. Lihan Shi
    12. Joy Zheng
    13. Ian Lam
    14. Xuekun Wu
    15. Shilong Liu
    16. Peishan Li
    17. Yi Zhu
    18. Ning Zhao
    19. Meenal Parakh
    20. Simran Serrao
    21. Imran A. Mohammad
    22. Chao-Yeh Chen
    23. Xiufeng Xie
    24. Tiffany Chen
    25. David Weinstein
    26. Greg Barbone
    27. Belgin Caglar
    28. John B. Sunwoo
    29. Fuxin Li
    30. Jia Deng
    31. Joseph C. Wu
    32. Sanfeng Wu
    33. Mengdi Wang

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity

  2. A high-throughput assay for the measurement of Ca2+-oscillations and insulin release from uniformly sized β-cell spheroids

    1. Stijn Robben
    2. Patricia Davidson
    3. Rita S Rodrigues Ribeiro
    4. Thomas Voets

    • Curated by eLife

      eLife Assessment

      In this valuable study, Robben et al. describe a 3D beta-cell spheroid platform, a tool allowing high-throughput monitoring of cytoplasmic calcium concentrations and insulin secretion, with calcium signals comparable to those recorded in primary pancreatic islets. The authors demonstrate the method by culturing MIN6 cells in a 3D culture system, and show solid evidence of its utility by recording calcium signals in a high-throughput format and characterizing these calcium signals using pharmacological tools. This highlights the potential utility of the 3D beta-cell spheroids for screening new pharmacological modulators of pancreatic beta-cell function.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  3. Autonomous Liquid-handling Robotics Scripting for Accessible and Responsible Protein Engineering

    1. Yuan Gao
    2. Yizhou Luo
    3. Wenzhuo Li
    4. Yunquan Lan
    5. Han Jiang
    6. Yongcan Chen
    7. Xiao Yi
    8. Boyang Li
    9. Hamid Alinejad-Rokny
    10. Teng Wang
    11. Lihao Fu
    12. Min Yang
    13. Tong Si

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  4. Direct MRI of Collagen

    1. Jason Daniel van Schoor
    2. Markus Weiger
    3. Emily Louise Baadsvik
    4. Klaas Paul Pruessmann

    • Curated by eLife

      eLife Assessment

      This fundamental work substantially advances our understanding of a major research question: whether collagen can be directly imaged with MRI. The evidence supporting the conclusion is compelling, with methods, data, and analyses that are more rigorous than those currently considered state-of-the-art. The work will be of high interest to MR physicists and clinicians, as collagen is the most abundant protein in the human body and plays an essential role in health.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  5. Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy

    1. See-Khai Lim
    2. Wen-Ching Lin
    3. Yi-Chung Pan
    4. Sin-Wei Huang
    5. Yao-An Yu
    6. Cheng-Hung Chang
    7. Che-Ming Jack Hu
    8. Chung-Yuan Mou
    9. Kurt Yun Mou

    • Curated by eLife

      eLife Assessment

      This important study presents the rational redesign and engineering of interleukin-7. The data from the integrated approach of using computational, biophysical, and cellular experiments are convincing. This paper is broadly relevant to those studying immunomodulation using biologics.

    Reviewed by eLife

    6 evaluationsAppears in 1 listLatest version Latest activity

  6. Generation of Chlorella vulgaris starch mutants and their biomass and lipid productivities under different culture media

    1. Ana C. Ramos
    2. Anna Hamilton
    3. Isabel Molina
    4. Patrick J. McGinn
    5. Sharon Regan

    Reviewed by Arcadia Science

    4 evaluationsAppears in 1 listLatest version Latest activity

  7. Reversing transgene silencing via targeted chromatin editing

    1. Sebastian Palacios
    2. Elia Salibi
    3. Eric Lu
    4. Ron Weiss
    5. Thorsten M. Schlaeger
    6. James J. Collins
    7. Domitilla Del Vecchio

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Rationally designed multimeric nanovaccines using icosahedral DNA origami for molecularly controlled display of SARS-CoV-2 receptor binding domain

    1. Qingqing Feng
    2. Keman Cheng
    3. Lizhuo Zhang
    4. Xiaoyu Gao
    5. Jie Liang
    6. Guangna Liu
    7. Nana Ma
    8. Chen Xu
    9. Ming Tang
    10. Liting Chen
    11. Xinwei Wang
    12. Xuehui Ma
    13. Jiajia Zou
    14. Quanwei Shi
    15. Pei Du
    16. Qihui Wang
    17. Guangjun Nie
    18. Xiao Zhao

    Reviewed by Rapid Reviews Infectious Diseases

    3 evaluationsAppears in 1 listLatest version Latest activity

  9. Kinetic properties of optogenetic site-specific DNA recombination by LiCre- loxP

    1. Alice Dufour
    2. Hélène Duplus-Bottin
    3. Thomas Boukéké-Lesplulier
    4. Eliane Casassa
    5. Gérard Triqueneaux
    6. Léo Tarbouriech
    7. Camille Darthenay-Kiennemann
    8. Agnès Dumont
    9. Catherine Moali
    10. Franck Vittoz
    11. Daniel Jost
    12. Gaël Yvert

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  10. RamanBot: Versatile high throughput Raman system

    1. Khaled Atia
    2. Robert Hunter
    3. Meshach Asare-Werehene
    4. Benjamin K. Tsang
    5. Hanan Anis

    Reviewed by Arcadia Science

    3 evaluationsAppears in 1 listLatest version Latest activity
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