Animal Behavior and Cognition

  2. Homosensory and heterosensory dishabituation engage distinct circuits in Drosophila

    1. Alexandros Charonitakis
    2. Sofia Pasadaki
    3. Eirini-Maria Georganta
    4. Kyriaki Foka
    5. Ourania Semelidou
    6. Efthimios MC Skoulakis

    • Curated by eLife

      eLife Assessment

      This study provides important findings on the neural circuits underlying dishabituation of the olfactory avoidance response in Drosophila. The data as presented provide solid evidence that the dishabituation involves distinct pathways from habituation. They show that reward-activated dopaminergic neurons provide input for within-modal dishabituation, while punishment-activated dopaminergic neurons provide input for cross-modal dishabituation. The work will interest neuroscientists, particularly behavioral neuroscientists working on habituation, neural circuits, and the dopaminergic system.

    Reviewed by eLife

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