Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)
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SciScore for 10.1101/2020.04.27.20077180: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: In the present study, we included all consecutive patients with positive SARS-CoV-2-RT-PCR (mucosal swab, pharyngeal or bronchoalveolar lavage) admitted to the Bundeswehrkrankenhaus Ulm in March and April 2020 after obtaining informed consent.
IRB: This project was approved by the local ethics committee of the University of Ulm (ref. no. 129-20) and conducted in accordance with the Declaration of Helsinki.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Furthermore, immunohistochemistry for CD3, CD68, CMV and EBV was performed using … SciScore for 10.1101/2020.04.27.20077180: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement Consent: In the present study, we included all consecutive patients with positive SARS-CoV-2-RT-PCR (mucosal swab, pharyngeal or bronchoalveolar lavage) admitted to the Bundeswehrkrankenhaus Ulm in March and April 2020 after obtaining informed consent.
IRB: This project was approved by the local ethics committee of the University of Ulm (ref. no. 129-20) and conducted in accordance with the Declaration of Helsinki.Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
Antibodies Sentences Resources Furthermore, immunohistochemistry for CD3, CD68, CMV and EBV was performed using prediluted antibodies on a VENTANA benchmark autostainer (Roche Tissue Diagnostics, Mannheim, Germany) following routine protocols. CD3suggested: NoneCD68suggested: NoneSoftware and Algorithms Sentences Resources All statistical analyses were conducted using GraphPad PRISM 6 (GraphPad Software Inc., San Diego, CA, USA). GraphPad PRISMsuggested: (GraphPad Prism, RRID:SCR_002798)GraphPadsuggested: (GraphPad Prism, RRID:SCR_002798)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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