A study on the impact of hyponatremia on hemodialysis patients with anxiety and depression

Objective Exploring the relationship between hemodialysis patients with anxiety and depression and hyponatremia, providing better ideas and treatment targets for the prevention and treatment of anxiety and depression in dialysis patients. Method 499 patients with chronic kidney disease from multiple hospitals in Inner Mongolia were selected and evaluated using the Anxiety and Depression Scale. Relevant clinical characteristics of the patients were collected and analyzed using SPSS statistical software. Result Grouping HD patients with blood sodium every 5mmol/L, it was found that the positive rate of depression was significantly different (P<0.05). The positive rate of depression showed a decreasing trend as blood sodium gradually increased. The distribution of blood sodium varies in HD patients with sleep disorders and decreased appetite (P<0.05). No significant effect of blood sodium was found in anxiety, anxiety combined with depression. Blood sodium is a protective factor affecting depression in hemodialysis patients. For every 1mmol/L increase in blood sodium, the risk of depression decreases by 11.1%. This study found that (blood sodium>140, ≤ 145mmol/L as a reference), the incidence of depression in HD patients with blood sodium between 130-135mmol/L was 2.505 times higher than that between 140-145mmol/L (OR=2.505), and the incidence of depression in HD patients with blood sodium between 125-130mmol/L was 12.308 times higher than that between 140-145mmol/L (OR=13.308). Conclusion Blood sodium is correlated with the physical and psychological conditions of HD patients. HD patients with hyponatremia are more prone to depression, and maintaining a normal range of blood sodium levels is more beneficial for HD patients.