A telomere-to-telomere genome assembly of Pythium species
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Pythium spp. include numerous important pathogens that affect both plants and animals, posing serious threats to agricultural production and the health of humans and livestock. Currently, high-quality genomic resources for these species are scarce, impeding the understanding of population evolution and the development of prevention and control strategies. Here, the first complete telomere-to-telomere (T2T) genome of Pythium sp. was produced by integrating NGS, PacBio HiFi,ONT and Hi-C data. The genome size is 59.9 Mb in total, with a scaffold N50 length of 3.5 Mb. BUSCO assessment indicated that the genome assembly achieved 94.91% (n=255) completeness. A total of 14,111 protein-coding genes were predicted, with 12,711 genes (90.08% of the total) annotated using functional databases. Additionally, we predicted 382 effectors. This T2T genome is an excellent resource for furthering the understanding of the evolutionary path and pathogenesis mechanisms of Pythium spp.
