Acute severe pancreatitis following induction with methylprednisolone in live donor kidney transplantation: A case report

Background Acute severe pancreatitis following kidney transplantation is a relatively rare complication. Its diagnosis and management are challenging due to the recent surgical state, altered postoperative physiology, and the effects of immunosuppressive therapy. Case Presentation: Here, we present a case of acute severe pancreatitis in the immediate postoperative period in a kidney transplant recipient. The disease process is complicated by multiorgan dysfunction syndrome (MODS), including acute respiratory distress syndrome (ARDS), hematemesis, and acute rejection. Despite these complications, prompt recognition and tailored supportive care with rational alteration of immunosuppressive treatment led to patient recovery and good graft function. Conclusion Acute severe pancreatitis in the early postoperative period following kidney transplantation is rare but potentially fatal. Early recognition, multidisciplinary management, and careful optimization of immunosuppressive therapy are crucial for improving outcomes and preserving graft function.