Acute Viral-Induced Myopathy Following COVID-19: A Case Report

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Abstract

Background and Clinical Significance: Coronavirus disease 2019 (COVID-19) has been associated with myopathies that may arise from immune dysregulation, autoimmunity, or possible direct viral injury, though the exact mechanisms remain unclear. Recogniz-ing these cases is clinically important, as they can resemble primary autoimmune my-opathies but may follow a different course and prognosis. Case Presentation: We report a 59-year-old previously healthy woman who developed acute myopathy shortly after COVID-19. She presented with diffuse myalgia, fatigue, exertional dyspnea, dizziness, fine motor difficulties, and urinary incontinence. Neurological examination showed preserved reflexes, no sensory deficits, and normal cerebrospinal fluid, excluding Guillain–Barré syndrome and transverse myelitis. Laboratory tests revealed elevated lactate dehydrogenase (616 U/L; ref. 105–205), alanine aminotransferase (239 U/L; ref. < 70), and plasma myoglobin (60–74 µg/L; ref.

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