Formulation and Evaluation Techniques in Novel Drug Delivery Systems

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Abstract

New drug delivery systems (NDDS) have significantly changed the pharmaceutical products with maximization of drug stability, patient compliance, and bioavailability. The present review elaborates on the different forms of NDDS, i.e., vesicular carriers such as liposomes and proniosomes, effervescent and mouth-dissolving drug delivery systems, and mucoadhesive drug delivery systems. New drug formulation methods including drug carrier systems using biopolymers, selection of excipients, and issues related to stability are elaborately discussed.Testing methodologies are necessary for safety and efficiency of drug products. Analytical characterization, in vivo and in vitro testing, and pharmacology screening are necessary for formulation success. Combination of nanotechnology and polymer-carriers has also escalated the significance of NDDS for overcoming solubility and targeted delivery problems. However, regulatory and scalability issues require further work on sustainable and patient-centred drug products.Emerging trends in drug delivery emphasize predictive modelling through the help of AI, intelligent therapeutics, and personalized medicine. In spite of the challenges faced, NDDS is marching ahead with the potential to bring revolutionary changes in future drugs. This new review has a snapshot of the existing status, assessment modes, and future of novel drug delivery technologies, highlighting their biggest contribution to contemporary medicine.

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