Advancements in Drug Delivery Systems from Chewable Tablets to Nanomedicine

Development of drug delivery systems has revolutionized drug formulation in pharmaceuticals to provide enhanced drug efficacy and compliance. The subsequent article describes the revolution from classic chewable tablets to emerging nanomedicine-based drugs. Chewable tablets are an inexpensive oral drug delivery in pediatric and geriatric patients with notwithstanding stability and formulation constraints. Targeted drug delivery revolutionized therapeutic specificity by reducing systemic side effects and enhancing drug bioavailability.Liposomal and particulate-based drug delivery systems have advanced therapeutic modality to a greater extent to realize FDA-approved nanomedicines with enhanced therapeutic performance. Naso-pulmonary drug delivery has also emerged to the forefront for respiratory care management using inhaled nanoparticles for direct and effective drug delivery. Regardless of all these technologies, regulatory approval, scale-up formulation of the product, and long-term safety issues remain at the center of attention.Theranostic approaches and image-guided drug delivery are revolutionizing the fate of drug delivery through real-time diagnosis and therapy. These new technologies hold the promise of precision medicine with enhanced targeting, monitoring, and patient response. With ongoing research, overcoming current challenges will unlock the potential of the next generations of drug delivery systems.