The Role of Liposomal Drug Delivery in Modern Medicine and the Expanding Potential of Nanocarriers

Liposomal drug delivery has transformed contemporary medicine with the supply of targeted, controlled, and effective drug release systems. Liposomal nanocarriers maximize drug bioavailability and reduce systemic toxicity, making them especially beneficial for cancer therapy and precision medicine. The paper points out development and progress in liposomal drug delivery with emphasis on mechanisms for targeted release of drugs and growing application of nanocarriers in contemporary therapeutics. Despite their advantages, the liposomal formulations are subjected to some strong disadvantages including rapid immune system clearance, tumor heterogeneity, and high-scale production. Despite these drawbacks, certain new developments by way of PEGylation, ligand-grafted liposomes, and hybrid lipid-polymer nanocarriers have proved promising and effective in bringing improvements to liposome stability and target specificity. In addition, artificial intelligence predictive modeling is becoming an effective approach for optimizing liposomal formulations to tailor treatment regimens to the patient.Also, liposomal nanoparticle use in the treatment of cancer has provided avenues for the development of new chemotherapy and gene therapy approaches for facilitating precision medicine. The review also illustrates current trends, including theranostic liposomes to facilitate real-time drug delivery and imaging and CRISPR-based liposomal gene therapy. The future is conjugating nanotechnology, bioengineering, and artificial intelligence in formulating the next generation of intelligent nanocarriers. Despite current limitations, liposomal preparations have unmatched promise to revolutionize drug delivery systems and precision medicine.