Development and Implementation of a Mixed Reality-Based System for Planning, Simulation, and Real-World Clinical Performance of Laparoscopic Myomectomy

Uterine fibroid is the most common benign gynecological tumor. Most are treated using laparoscopic myomectomy. Clinical issues associated with myomectomy that warrant attention include intraoperative bleeding and injury to adjacent structures. Surgical complications are common, and surgical safety and homogeneity need to be further improved. This project aims to construct a full-process planning scheme for individualized laparoscopic myomectomy via several steps. First, pelvic magnetic resonance imaging will be used to achieve automatic segmentation and three-dimensional reconstruction to visually present details such as fibroid number and size and the relationship of each fibroid with the uterine wall. Then, based on physical simulation technology, an interactive surgical operation simulation system will be established, and a laparoscopic surgical planning and simulation prototype system developed. Next, using mixed reality technology, real-time three-dimensional visualization of uterine fibroids during surgery will be achieved. Finally, safety and effectiveness will be evaluated in a randomized controlled trial. A laparoscopic surgical planning and simulation prototype system will be developed, followed by production of an engineering prototype. The aims are to significantly enhance the precision of laparoscopic myomectomy, improve safety of the surgery, enable standardization, and enhance surgical training. The system will also provide new ideas and pathways for other gynecological surgeries.